Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 309-643-4 | CAS number: 100656-54-0 The product obtained by acid leaching of copper speiss. Composed primarily of antimony, arsenic and lead with high precious metal content.
Genetic toxicity: in vitro
Administrative data
- Endpoint:
- genetic toxicity in vitro
- Remarks:
- Type of genotoxicity: gene mutation
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: no GLP (but other Quality Assurance); software
Cross-referenceopen allclose all
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to other study
Data source
Reference
- Reference Type:
- other: software
- Title:
- Unnamed
- Year:
- 2 010
Materials and methods
- Principles of method if other than guideline:
- The UVCB substance as complex substance is classified regarding germ cell mutagenicity by applying rules for classification of mixtures (EU CLP guidance section 3.5.3 pg 293ff). The classification criteria (as set out in EU CLP Guidance Annex I: 3.5.2.2 pg 287) can be used to estimate effects derived from that classification/hazard.
- GLP compliance:
- no
- Remarks:
- (other quality assurance)
- Type of assay:
- other: calculation based on Classification
Test material
- Reference substance name:
- Residues, copper speiss acid leaching
- EC Number:
- 309-643-4
- EC Name:
- Residues, copper speiss acid leaching
- Cas Number:
- 100656-54-0
- IUPAC Name:
- Residues, copper speiss acid leaching
- Details on test material:
- Typical across industry as defined in IUCLID 1.2.
Constituent 1
Results and discussion
Any other information on results incl. tables
The mixture toxicity rules can be used to classify Germ cell mutagenicity
Applicant's summary and conclusion
- Conclusions:
- The tool can be used to predict Germ cell mutagenic effect and to classify the UVCB substances. In some cases no classification will be derived based on the estimates in the study. See Section 2 for potential resulting classifications.
- Executive summary:
The study provides an estimate of the Germ cell mutagenicity hazard, derived on basis of the Classification outcome (Mixture toxicity rules) from a Typical industry as defined in IUCLID section 1.2/1.4. In some cases no classification will be derived based on the estimates in the study.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
