Registration Dossier
Registration Dossier
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EC number: 479-330-6 | CAS number: 67226-45-3
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
96-Hour EC50 of > 100 mg/L
Key value for chemical safety assessment
Additional information
One study according to OECD Guidelines for Testing of Chemicals (1992) No 203, "Fish, Acute Toxicity Test" referenced as Method C.1 of Commission Directive 92/69/EEC (which constitutes Annex V of Council Directive 67/548/EEC), US CFR Title 40 Part 797 Section 1400 and US EPA Draft Ecological Effects Test Guideline OPPTS 850.1075 was performed to assess the acute toxicity of the test material to fish (Oncorhynchus mykiss). The test material degraded immediately on contact with water forming N-butylpyridinum, hydrochloric acid and aluminium oxides. Following a preliminary range-finding test fish were exposed to a homogenous dispersion of the test material, at a single concentration of 100 mg/L for a period of 96 hours under semi-static test conditions. The 96-Hour EC50 based on nominal test concentrations was greater than 100 mg/L and correspondingly the No Observed Effect Concentration was 100 mg/L. The test samples were analysed for the degradation product N-butylpyridinium chloride as a marker. Analysis of the test preparations at 0 (fresh media), 24, 48, 72 (old and fresh media) and 96 hours (old media) showed measured test concentrations of 1 -Butylpyridiniumchloride to range from 95% to 98% of nominal and so the results are based on nominal test concentrations.
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