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Hydrolysis of an organic chemical is the transformation process in which a water molecule or hydroxide ion reacts to form a new carbon--oxygen bond. Chemicals that have a potential to hydrolyze include alkyl halides, amides, carbamates, carboxylic acid esters and lactones, epoxides, phosphate esters, and sulfonic acid esters (Hams, 1982). source: Hams, J.C. 1982. Rate of hydrolysis. In; Handbook of Chemical Property Estimation Methods. W.L. Lyman, W.F. Reehl, and D.H. Rosenblastt, eds. Mcgraw-Hill Book Co., New Vork, NY. The chemical components of naphthenic acids are hydrocarbons that are not subject to hydrolysis because they lack functional groups that hydrolyse.