Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 201-152-2 | CAS number: 78-87-5
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Two short-term toxicity tests were conducted with the fathead minnow (Pimephales promelas) exposed to 1,2-dichloropropane under flow-through conditions, in general accordance to standard methods, and resulted in 96-hour LC50 values of 127 and 140 mg/L for a geometric mean 96-hour LC50 value of 133 mg/L..
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 133 mg/L
Additional information
The 1,2 -dichloropropane studies by USEPA (1984) and Geiger et al. (1985) were selected as the key freshwater fish studies because both were conducted with under flow-through conditions with measured confirmation of doses and in general accordance with standard methods. Since both tests were conducted with the same test species (fathead minnow) and presented similar toxicity values (140 and 127 mg/L, respectively), the geometric mean of these two 96 -hour LC50 values of 133 mg/L will be used to reflect the toxicity of this test substance to freshwater fish.
The remaining 5 supporting studies were not considered key studies because either the test system was unsuitable (e.g. static test) or insufficient information was available for assessing their reliability. These tests were conducted with various fish species (fathead minnow, bluegill, dab, guppy, tidal silverside) and reported 96 -hour LC50 values ranging from 61 -320 mg/L; one test had a 7 -day LC50 values of 116 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
