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Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Reference
Endpoint:
bioaccumulation in aquatic species: fish
Type of information:
other: discussion in comparison with naturally occurring structurally related hectorite
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
secondary literature
Reason / purpose for cross-reference:
other: see Remarks
Remarks:
general substance background and toxicokinetics summary
Qualifier:
no guideline required
Guideline:
other: discussion in comparison with naturally occurring structurally related hectorite
Principles of method if other than guideline:
discussion in comparison with naturally occurring structurally related hectorite
GLP compliance:
no
Remarks on result:
other: see Remarks
Remarks:
see Any Other Information on Results

The substance is an inorganic solid structurally related to naturally occurring hectorite that is insoluble in water and n-octanol.

The amount of soluble free Na, Mg, Li, F and Si that would be made available will not contribute to the background levels of these ions already present in the environments. Bioaccumulation in aquatic/sediment organisms will not occur in excess of exposure to naturally occurring sediments.

Besides, as the substance is poorly soluble (disperses in water to form a colloidal suspension), low concentrations are expected in the aquatic compartment. Low quantities which might be taken up are considered to be not bioavailable as it is known that based on the lack of hydrolysis, no toxicologically relevant absorption of Na, Mg, Li or F should occur, and with regard to Si, if there was any absorbed, Si levels are known to be rapidly excreted in urine and faeces. Thus, the substance contains no bioaccumulation potential.

Conclusions:
The substance is an inorganic solid structurally related to naturally occurring hectorite that is insoluble in water and n-octanol.
The amount of soluble free Na, Mg, Li, F and Si that would be made available will not contribute to the background levels of these ions already present in the environments. Bioaccumulation in aquatic/sediment organisms will not occur in excess of exposure to naturally occurring sediments.

Besides, as the substance is poorly soluble (disperses in water to form a colloidal suspension), low concentrations are expected in the aquatic compartment. Low quantities which might be taken up are considered to be not bioavailable as it is known that based on the lack of hydrolysis, no toxicologically relevant absorption of Na, Mg, Li or F should occur, and with regard to Si, if there was any absorbed, Si levels are known to be rapidly excreted in urine and faeces. Thus, the substance contains no bioaccumulation potential.
Executive summary:

The substance is an inorganic solid structurally related to naturally occurring hectorite that is insoluble in water and n-octanol.

The amount of soluble free Na, Mg, Li, F and Si that would be made available will not contribute to the background levels of these ions already present in the environments. Bioaccumulation in aquatic/sediment organisms will not occur in excess of exposure to naturally occurring sediments.

Besides, as the substance is poorly soluble (disperses in water to form a colloidal suspension), low concentrations are expected in the aquatic compartment. Low quantities which might be taken up are considered to be not bioavailable as it is known that based on the lack of hydrolysis, no toxicologically relevant absorption of Na, Mg, Li or F should occur, and with regard to Si, if there was any absorbed, Si levels are known to be rapidly excreted in urine and faeces. Thus, the substance contains no bioaccumulation potential.

Description of key information

This substance is not expected to bioaccumulate in the aquatic environment

Key value for chemical safety assessment

Additional information

The substance is an inorganic solid structurally related to naturally occurring hectorite that is insoluble in water and n-octanol.

The amount of soluble free Na, Mg, Li, F and Si that would be made available will not contribute to the background levels of these ions already present in the environments. Bioaccumulation in aquatic/sediment organisms will not occur in excess of exposure to naturally occurring sediments.

Besides, as the substance is poorly soluble (disperses in water to form a colloidal suspension), low concentrations are expected in the aquatic compartment. Low quantities which might be taken up are considered to be not bioavailable as it is known that based on the lack of hydrolysis, no toxicologically relevant absorption of Na, Mg, Li or F should occur, and with regard to Si, if there was any absorbed, Si levels are known to be rapidly excreted in urine and faeces. Thus, the substance contains no bioaccumulation potential.

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