Registration Dossier
Registration Dossier
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EC number: 202-551-4 | CAS number: 97-00-7
Sensitisation data (human)
Administrative data
- Endpoint:
- sensitisation data (humans)
- Type of information:
- other: Case report
- Adequacy of study:
- supporting study
- Study period:
- 1985
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: single case
Data source
Reference
- Reference Type:
- publication
- Title:
- Contact urticaria to DNCB
- Author:
- van Hecke, E; Santosa, S.
- Year:
- 1 985
- Bibliographic source:
- Contact Dermatitis 12 (5): 282 (1985)
Materials and methods
- Type of sensitisation studied:
- skin
- Study type:
- case report
Test guideline
- Qualifier:
- no guideline required
- GLP compliance:
- no
Test material
- Reference substance name:
- 1-chloro-2,4-dinitrobenzene
- EC Number:
- 202-551-4
- EC Name:
- 1-chloro-2,4-dinitrobenzene
- Cas Number:
- 97-00-7
- Molecular formula:
- C6H3ClN2O4
- IUPAC Name:
- 1-chloro-2,4-dinitrobenzene
Constituent 1
Method
- Ethical approval:
- not applicable
- Subjects:
- 1
- Clinical history:
- alopecia areata
- Controls:
- none
- Route of administration:
- dermal
Results and discussion
- Results of examinations:
- One 26 year old male developed contact urticaria after repeated dermal treatment with DNCB for alopecia areata.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
