Registration Dossier
Registration Dossier
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EC number: 205-362-5 | CAS number: 139-42-4
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
48 h LL50 > 100 mg/L, 48 h NOELR >= 100 mg/L, Daphnia magna, OECD 202, EU Method C.2, RCC 2007 (read across to cerium carbonate).
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 100 mg/L
Additional information
The 48 hr-acute toxicity of cerium carbonate to Daphnia magna was studied under static conditions. During the study the daphnids were exposed to control and test material at nominal concentration of 100 mg of dry substance /L (loading rate) for 48 hours. Mortality and immobilization were observed daily. In the control and at the loading rate of 100 mg/L, no immobilized test organisms were observed during the test period of 48 hours. Thus, the 48 hour LL50 was > 100 mg/L and the 48h NOELR were >= 100 mg/L.
No short-term toxicity data for aquatic invertebrates is available for the registered substance, cerium oxalate. A valid study has been provided on the structural analogue, cerium carbonate. The similar toxicological profiles of cerium carbonate and cerium oxalate, along with the structural similarity, mean that this is considered to be an acceptable read-across.
The study was performed in line with a recognised OECD guideline and to GLP standards. It is assigned a score of 2 in line with the reliability scoring system of Klimisch (1997), based on the fact that a read across approach has been used.
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