Registration Dossier
Registration Dossier
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EC number: 700-776-7 | CAS number: -
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
Description of key information
The test substance does not significantly accumulate in organisms.
Key value for chemical safety assessment
Additional information
The bioaccumulation potential of the substance was tested in a guideline study following OECD 305 (Institute of Ecotoxicology, 1987). Japanese carp (Cyprinus carpio) were exposed to the substance for 8 weeks. The determined bioconcentration factor was <16 and the test item does not significantly accumulate in fish. Even though the test was conducted at the limit of solubility it is regarded as acceptable in a weight of evidence.
Therefore, the results are supported by three different model calculations. BCF values are calculated for the three different main components and resulted in BCF values for all three main components well below 100: US EPA T.E.S.T v4.0.1 using the consensus method resulted in a BCF of 5.25 - 58.90. US EPA EPISuite v4.10 (BCF BAF v3.01) revealed a BCF of 0.978 - 40.3 L/kg wet-wt. CATALOGIC v5.11.5 (BCF base-line model v2.05) resulted in a BCF of 5.87 - 7.43 with all mitigating factors applied. Even though the structural domain was correct with only < 17% (> 83% unknown) the results support the overall conclusion in a weight of evidence. Nevertheless, the results can be used in the weight of evidence to give an indication if the test substance has a bioaccumulative potential.
In overall conclusion, regarding all available information the test item does not significantly accumulate in organisms.
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