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Diss Factsheets

Physical & Chemical properties

Water solubility

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2003
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Version / remarks:
- EEC Directive 92/69, A.6
Deviations:
not specified
GLP compliance:
yes
Type of method:
flask method
Water solubility:
9.9 mg/L
Temp.:
20 °C
pH:
7.11 - 7.15
Remarks on result:
other: ±1.1
Details on results:
The saturation concentration of test item at room temperature was estimated by a simplified flask method in the preliminary test to be higher than 10-2 g/l. Therefore, the flask shaking test was performed.

The concentrations were determined after a shaking time of 24 hours, 48 hours and 72 hours, respectively at 30°C. Afterwards the samples were equilibrated for 24 hours at 20°C. The measured results differ by less than 15 %. Therefore the study is considered to be valid.
Conclusions:
The water solubility of test substance was determined to be 9.9 mg/L at 20°C at pH 7.1
Executive summary:

In this guideline (OECD 105) study conducted to GLP standards, the water solubility of the test material (EC 444-860-9) was determined to be 9.9 mg/L at 20°C at pH 7.1 (slightly soluble).

Description of key information

Study conducted to recognised testing guidelines with GLP.

Key value for chemical safety assessment

Water solubility:
9.9 mg/L
at the temperature of:
20 °C

Additional information

The determination was conducted by flask method (9.9 mg/L at 20°C at pH 7.1).