Registration Dossier

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

DEGDB:

Biodegradability:

- Key study, reliability 1, OECD 301B - Modified stturm test - readily biodegradable

- Supporting study, reliability 1, OECD 301D - Closed Bottle Test - not readily biodegradable

- Supporting study, reliability 1, ISO Method 11734 - Anaerobix Biodegradability of Organic Chemicals - Ultimately biodegradable under anaerobic conditions

- Supporting study, reliability 2, OECD 301A - Ready Biodegradability: DOC Die Away Test - readily biodegradable

DPGDB:

Biodegradability:

- Key study, reliability 1, OECD 301B - Modified sturm test - readily biodegradable

- Supporting study, reliability 1, OECD 301D - Closed Bottle Test - not readily biodegradable

- Supporting study, reliability 1, ISO Method 11734 - Anaerobix Biodegradability of Organic Chemicals - Ultimately biodegradable under anaerobic conditions

- Supporting study, reliability 2, OECD 301A - Ready Biodegradability: DOC Die Away Test - readily biodegradable

TEGDB:

Biodegradability:

- Key study, reliability 1, OECD 301B - CO2 Evolution Test - readily biodegradable

- Supporting study, reliability 1, OECD 301D - Closed Bottle Test - not readily biodegradable

- Supporting study, reliability 1, ISO Method 11734 - Anaerobix Biodegradability of Organic Chemicals - Ultimately biodegradable under anaerobic conditions

- Supporting study, reliability 2, OECD 301A - Ready Biodegradability: DOC Die Away Test - readily biodegradable

Additional information

This substance is a reaction mass of dipropylene glycol dibenzoate (DPGDB), diethylene glycol dibenzoate (DEGDB) and triethylene glycol dibenzoate (TEGDB).  No testing has been performed on the reaction mass itself but data are available for DPGDB, DEGDB and TEGDB. 

 

The key value used in the chemical safety assessment is:

Biodegradation in water; readily biodegradable (all components)

 

All studies were performed according to international test guidelines and in compliance with GLP. They are presented below by component. Where no data exist an overall statement that applies to the reaction mass has been made.

 

Modified Sturm ready biodegradation tests were performed on two of the components (DEGDB and DPGDB). In each test the positive control substance demonstrated rapid biodegradation (greater than 60% after 6/7 days) confirming theinoculum was viable and that the test was valid.Substances are considered to be readily degradable in this test if CO2 production is equal to or greater than 60% of the theoretical value within ten days of the level achieving 10%. For TEGDB a CO2 Evolution Test according to OECD 301B has been performed and the substance has been shown to be also readily biodegradable.

 

BOD/COD and anaerobic biodegradation tests were also performed on each component.

 

No further testing is proposed or required.

 

Biodegradation in water: screening tests

 

DPDGB

In the modified Sturm test, DPGDB was found to have degraded by 6% after 2 days, 62% after 12 days, and by 85% at the end of the 28 day biotic phase of the test (HLS 1998, VCL236/972256).

In this test, DPGDB met the criteria for ready biodegradability.

 

DEGDB

In the modified Sturm test,DEGDB was found to have degraded by 17% after 2 days, 71% after 10 days, and by 93% at the end of the 28 day biotic phase of the test (HLS 1998, VCL246/972257).

In this test, DEGDB met the criteria for ready biodegradability.

 

TEGDB

In the CO2 evolution test, TEGDB was found to have degraded by 16% after 2 days, 62% after 7 days, and by 92% at the end of the 28 day biotic phase of the test (HLS 1998, VCL287/973177).

In this test, TEGDB met the criteria for ready biodegradability.

 

In all cases the BOD / COD studies show all constituents to be inherently biodegradable and the anaerobic study showed them to be anaerobically biodegradable.

 

OTHER ENDPOINTS

 

Biodegradation in water and sediment: simulation tests

In accordance with the adaptations found in column 2 of Annex IX, simulation studies of biodegradation in water and sediments are waived due to the demonstrated ready biodegradation of the components of the substance.

 

Biodegradation in soil

In accordance with the adaptations found in column 2 of Annex IX, simulation studies of biodegradation in soils are waived due to the demonstrated ready biodegradation of the components of the substance. 

 

Mode of degradation in actual use

No data available.