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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
developmental toxicity
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
other: Authoritative data base
Title:
Danish QSAR study for CAS No.: 59690-88-9
Author:
Danish EPA Model
Year:
2012
Bibliographic source:
QSAR predictions by Danish Environmental Protection Agency (EPA)model powered by OASIS database:- Commercial

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: modelling database
Principles of method if other than guideline:
Teratogenicity (human). Multicase model.
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
(3-aminophenyl)uronium chloride
EC Number:
261-858-1
EC Name:
(3-aminophenyl)uronium chloride
Cas Number:
59690-88-9
Molecular formula:
C7H9N3O.ClH
IUPAC Name:
(NZ)-3-amino-N-[amino(hydroxy)methylidene]anilinium chloride
Details on test material:
- Name of test material : (3-aminophenyl)uronium chloride

Test animals

Species:
other: human
Strain:
not specified

Administration / exposure

Type of inhalation exposure (if applicable):
not specified
Vehicle:
not specified

Results and discussion

Results: maternal animals

Effect levels (maternal animals)

Basis for effect level:
other: effect type not specified

Results (fetuses)

Fetal abnormalities

Abnormalities:
not specified

Overall developmental toxicity

Developmental effects observed:
not specified

Applicant's summary and conclusion

Conclusions:
Teratogenicity of (3-aminophenyl)uronium chloride is estimated to give negative result.
Executive summary:

Teratogenicity of (3-aminophenyl)uronium chloride is estimated to give negative result.