Registration Dossier
Registration Dossier
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EC number: 265-004-9 | CAS number: 64665-57-2
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
No studies available. To estimate the toxicokinetics properties of the substance, physicochemical parameters are utilised (Regulation (EC) No 1907/2006, Annex VII, Section 8.8.1)
Key value for chemical safety assessment
- Bioaccumulation potential:
- low bioaccumulation potential
- Absorption rate - oral (%):
- 100
- Absorption rate - dermal (%):
- 100
- Absorption rate - inhalation (%):
- 10
Additional information
physicochemical parameters used for toxicokinetic Endpoint summary:
Parameter |
Value used for CSR |
Molecular weight |
155.13 g/mol |
Melting point |
Decomposition at approx. 230-231 °C. No defined melting point was detected. |
Boiling point |
Decomposition at approx. 230-231 °C. No defined boiling point was detected. |
Density |
1.32 g/cm3 |
Vapour pressure |
0.004 kPa (value of Tolyltriazole) |
Partition coefficient n-octanol/water (log POW) |
1.087 |
Water solubility |
Water Solubility at 25 deg C (mg/L): 5.5e+004 (Epi-Suite) No value yet, but significantly higher than for TTA |
pH |
11.5-12 (at 25 °C), NaOH excess 2% |
pKa |
8.85 (at 25 °C) |
Particle size |
>100 µm |
Based on these parameters, the bioaccumulation potential is judged as low (log POW< 4).
The substance is a solid with a high boiling point and a low Vapour pressure, the particle size is large, which leads to a low absorption rate by inhalation. For dermal and oral Absorption rate 100 % are assumed by default.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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