Registration Dossier

Administrative data

Endpoint:
toxicity to microorganisms
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
other: Authoritative data base
Title:
Danish QSAR study for CAS No.: 98-37-3
Author:
Danish EPA Model
Year:
2012
Bibliographic source:
QSAR predictions by Danish Environmental Protection Agency (EPA)model powered by OASIS database:-DK-EPA

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: modelling database
Principles of method if other than guideline:
Multicase model is used to estimate IGC50 (46h) of tetrahymena pyriformis.
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
3-amino-4-hydroxybenzenesulphonic acid
EC Number:
202-662-8
EC Name:
3-amino-4-hydroxybenzenesulphonic acid
Cas Number:
98-37-3
Molecular formula:
C6H7NO4S
IUPAC Name:
3-amino-4-hydroxybenzene-1-sulfonic acid
Test material form:
solid: crystalline
Details on test material:
- Name of test material : 3-amino-4-hydroxybenzenesulphonic acid
-Substance type-organic
-physical state-crystalline solid.

Sampling and analysis

Analytical monitoring:
not specified

Test solutions

Vehicle:
not specified

Test organisms

Test organisms (species):
Tetrahymena pyriformis

Study design

Test type:
not specified
Water media type:
not specified
Total exposure duration:
46 h

Results and discussion

Effect concentrations
Duration:
46 h
Dose descriptor:
other: IG50
Effect conc.:
668.187 mg/L
Nominal / measured:
estimated
Conc. based on:
test mat.
Basis for effect:
growth inhibition

Applicant's summary and conclusion

Conclusions:
Toxicity to micro-organisms (IG50) of 3-amino-4-hydroxybenzenesulphonic acid in Tetrahymena pyriformis is estimated at dose concentration of l 668.1873 mg/L in 46 h.
Executive summary:

Toxicity to micro-organisms (IG50) of 3-amino-4-hydroxybenzenesulphonic acid in Tetrahymena pyriformis is estimated at dose concentration of 668.1873 mg/L in 46 h.