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Toxicological information

Direct observations: clinical cases, poisoning incidents and other

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Administrative data

Endpoint:
direct observations: clinical cases, poisoning incidents and other
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Secondary literature

Data source

Reference
Reference Type:
secondary source
Title:
Patty's Toxicology
Author:
Bingham E, et al.
Year:
2003
Bibliographic source:
Bingham E (ed.) Patty's Toxicology. Aliphatic Carboxylic Acids, Saturated. John Wiley & Sons, Inc. Fifth Edition, volume 5. 694-777. New York.

Materials and methods

Study type:
other: occupational study
Endpoint addressed:
other: inhalation
Test guideline
Qualifier:
no guideline available
GLP compliance:
not specified

Test material

Constituent 1
Reference substance name:
Formic acid
EC Number:
200-579-1
EC Name:
Formic acid
Cas Number:
64-18-6
IUPAC Name:
formic acid
Test material form:
not specified

Method

Subjects:
workers in a textile plant
Route of exposure:
inhalation
Reason of exposure:
unintentional, occupational
Exposure assessment:
not specified

Results and discussion

Clinical signs:
Workers exposed to formic acid in a textile plant reported nausea from vapor concentrations around 15ppm.

Applicant's summary and conclusion

Conclusions:
Formic acid can cause nausea if inhaled at concentration around 15ppm.