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EC number: 203-892-1 | CAS number: 111-65-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Endpoint summary
Administrative data
Description of key information
Additional information
There are measured acute toxicity data available for octane on fish (Morrow et al. 1975). However, due to significant methodological deficiencies this investigation is considered not realiable. Therefore, an LL50 (96 h) was calculated using the Petrotox computer model (v. 3.04), which combines a partitioning model used to calculate the aqueous concentration of hydrocarbon components as a function of substance loading with the Target Lipid Model used to calculate acute and chronic toxicity of non-polar narcotic chemicals. Petrotox computes toxicity based on the summation of the aqueous-phase concentrations of hydrocarbon block(s) that represent a hydrocarbon substance and membrane-water partitioning coefficients (KMW) that describe the partitioning of the hydrocarbons between the water and organism. The estimated freshwater fish 96-h LL50 (Lethal Loading Rate) value is 2.587 mg/L. Also the chronic toxicity was estimated with this model, resulting in a 28-day NOELR (No Observed Effect Loading Rate) value of 0.579 mg/L.
There are measured acute toxicity data available for octane on five different species of freshwater and marine aquatic invertebrate species (Adema & van den Bos Bakker 1987, Bobra et al. 1983, Donkin et al. 1989, Abernethy et al. 1986). The data provided by Adema & van den Bos Bakker (1987) are considered most realiable and a test conducted with Daphnia is chosen as key study. The acute toxicity, as measured by immobilisation of Daphnia and mortality to Chaetogammarus and Mysidopsis, was evaluated in fresh- and saltwater by using water accomodated fractions (WAFs). Octane produced acute toxicity to Daphnia, Chaetogammarus and Mysidopsis at 0.66 mg/L. Measured data on chronic toxicity are read-across to hydrocarbons, C7-C9, n-alkanes, isoalkanes, cyclics based on a category approach. A study of the chronic toxicity, as measured by survival, sublethal effects, reproduction, and length of first generation adults, conducted with Daphnia using WAFs (Wilbury Laboratories 2004) resulted in a NOELR of 1 mg/L.
As regards toxicity to algae measured data are available but not considered reliable (Brooks et al. 1977). Thus, an EL50 (72 h) and a NOELR (72 h) were calculated using the Petrotox computer model (v. 3.04). The estimated freshwater algae 72-h EL50 (Effect Loading Rate) and NOELR (No Observed Effect Loading Rate) values are 2.084 and 0.466 mg/L, respectively, based on biomass. With the same model toxicity to microorganisms were calculated. The estimated protozoan, Tetrahymena pyriformis, 48-hr EL50 value is 10.86 mg/L based on growth inhibition.
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