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Description of key information

There are no toxicokinetic studies available.

Key value for chemical safety assessment

Bioaccumulation potential:
no bioaccumulation potential

Additional information

1,4-bis[(2-ethyl-6-methylphenyl)amino]anthraquinone (Reinblau RLW) is insoluble in water (the water solubility of the test item was not detectable with a value lower than 0.00002 g/l) and has a log Pow of > 6.2 (according to the OECD 117 the partition coefficient (log Pow) was determined to be above 6.2 at 25°C and a logPow of 8.76 extrapolated).

Reinblau RLW has a low acute toxicity (LD50 oral >5000 mg/kg bw ; LD50 dermale > 2000 mg/kg bw). The substance is not irritating to the skin and eyes and has no sensitising potential. Reinblau RLW was negative in all in-vitro gene mutation assays with and without metabolic activation. No toxification via metabolic activation of parent compounds are therefore expected.

The NOAEL in a repeated dose study was 1000 mg/kg bw.