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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Long-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Description of key information

21d-EC10 (Daphnia magna) > solubility limit; iSafeRat® High-Accuracy-Quantitative Structure-Activity Relationship; KREATiS (2022).

Key value for chemical safety assessment

Additional information

To strengthen the reliability of the HA-QSAR prediction and the category approach, one experimental chronic daphnia study is available on the source substance, Solvent Blue 104 (CAS No 116-75-6). In addition, a testing proposal for a chronic daphnia study is requested on the source substance, Solvent Green 28 (CAS No 4851-50-7). Both substances are members of the category. See the category approach justification document, attached in section 13, for further details.


Global overview of the category approach for the endpoint:
























 



Solvent Violet 36



Solvent Green 3



Reinblau RLW



Reinblau BLW



Solvent Blue 104#



Solvent Green 28



Long-term toxicity to aquatic invertebrates



21d-EC10 (D.magna) > solubility limit*



21d-EC10 (D.magna) > solubility limit*



21d-EC10 (D.magna) > solubility limit*



21d-EC10 (D.magna) > solubility limit*



21d-NOEC (D.magna) ³ 1.0 mg/L (nominal)$


 


21d-EC10 (D.magna) > solubility limit*



Testing proposal (OECD TG 211)



# not registered by LANXESS, data with letter of access


* iSafeRat® High Accuracy QSAR predictions (KREATiS, 2022)