Registration Dossier

Physical & Chemical properties

Endpoint summary

Administrative data

Description of key information

Additional information

Appearence :

On the basis of physical observation and sense of smell; chlorocresol was found to be a colourless organic solid having characteristic odour.

 

Melting point :

The experimental value of the melting point as determined by the capillary method for chlorocresol was found to be 98.2°C at atmospheric pressure of 975 hPa. This value of melting point when converted at 101 325 Pa found to be equivalent to 102.05 °C. No decomposition and no sublimation of chlorocresol was observed at the melting point temperature. Supporting studies shows value different from Key study due to difference in the estimation conditions. However, for the purpose of chemical safety assessment key study value 102.05 °C shall be considered.

 

Boiliing point :

The experimental value of the boiling point of chlorocresol by the distillation method was observed to be 170.9°C at 975 hPa. Also, the chemical did not decompose at the boiling temperature. This value when converted at 101 325 Pa found to be equivalent to 177.60 °C. Supporting study shows value different from Key study due to difference in the estimation conditions. However, for the purpose of chemical safety assessment key study value 177.6 °C shall be considered.

 

Density :

The bulk density of chlorocresol by the mass by volume method was found to be 0.709 g/cm3 at room temperature of 30 °C. This value when converted for 20 deg C found to be equivalent to 0.472.

Supporting studies shows value different from Key study due to difference in the estimation conditions. However, for the purpose of chemical safety assessment key study value 0.472 shall be considered.

Particle size distribution :

The particle size distribution (granulometry) of chlorocresol by the sieve analysis method was found to be in the range of 1700 micrometer to 2360 micrometer. Majority of the particles were in the size of 2000 micrometer (56.43 %).

 

Vapopur pressure:

Vapour pressure of chlorocresol was found to be 0.05 mmHg at 200C. This value when converted into Pascal (Pa) found to be equivalent to 6.66 Pa at a temperature of 200C.

 

Partition co-efficient :

The experimental value of octanol water partition co-efficient (log Pow) of chlorocresol was found to be 0.477 at 30 degC and pH of 5.03. This value indicates that chlorocresol is relatively hydrophobic in nature.

Supporting study shows value different from Key study due to difference in the estimation conditions. However, for the purpose of chemical safety assessment key study value 0.477 shall be considered.

 

Water solubility :

The water solubility of chlorocresol was found to be 400 mg/L at 30°C using shake flask method indicating that test substance is soluble in water.

Sloubility in Organic solvent/fat solubility:

The solubility of the chlorocresol in ethanol was found to be 500 g/L and in toluene was 300 g/L.

Surface tension :

In accordance with coloumn 2 of Annex VII, this end point was waived since chlorocresol is a solid substance and surface activity is not a deisred property of the solid.

 

Flash point :

The flash point of a substance is the lowest temperature at which it can form an ignitable mixture in air. The experimental value of flash point of chlorocresol was found to be 81.1 degC at room temperature of 30°C and normal atmospheric pressure of 975 hPa indicating that substance is not flammable. This value when converted for 101 325 pascal found to be equivalent to 84.28 degC.

 

Auto flammability:

The auto ignition temperature or kindling point of a substance is the lowest temperature at which it will spontaneously ignite in a normal atmosphere without an external source of ignition, such as a flame or spark. The auto ignition temperature of chlorocresol was determined in the laboratory but it was found that this chemical do not catch fire at room temperature of 30°C and atmospheric pressure of 975 hPa. Thus it can be concluded that chlorocresol is not auto flammable.

 

Flammability:

Chlorocresol was found to be flammable when an ignition source having temperature of around 950°C was brought in close contact with it. However, such high temperature do not exist under normal conditions of use or transportation and hence chlorocresol is considered to be a non-flammable solid

 

Explosiveness:

In accordance with column 2 of Annex VII, this testing was considered for waiver since there are no chemical groups associated with explosive properties in chlorocresol

 

Oxidising properties:

Chlorocresol was found to be oxidising since 31.3 ml of KMnO4 was required for getting the end point of the redox titration for 100 g of chlorocresol.

 

Stability of organic solvents:

Chlorocresol was found to be stable in organic solvent dichloro methane and no degradation products were formed after 24 hours as evident from the GC-MS chromatogram obtained at 0 hours and that obtained after 24 hours.

 

pH:

The pH of 1% volume by volume solution of chlorocresol was found to be 5.25 suggesting that the chemical is weakly acidic in nature. The temperature of the 1% mixture was 30°C

Dissociation Constant:

The average experimental Pka value of chlorocresol at 30 deg C was found to be 0.000000001056 x 10-9. This value at 20 deg C is equivalent to 0.000000000704 x 10-9.

Viscosity:

This end point was considered for waiver since viscosity is an internal property of a liquid that offers resistance to flow and chlorocresol is a solid substance and hence this testing was considered scientifically unjustified