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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Description of key information




In accordance with column 2 of REACH regulation annex IX, 9.3.2., a bioaccumulation study does not need to be conducted because direct and indirect exposure of the aquatic compartment is unlikely or if the logKow of the substance is < 3.


The substance is readily biodegradable, reducing the risk of exposure to the environment. 


Additionally, the substance has a logKow of 3.1, closely missing the criterion to waive the bioaccumulation study in accordance with REACH Annex IX 9.3.2. , column 2 (criterion of logKow < 3). Based on the BDGMA logKow of 3.1, cacluated BCFs are 86.1 (according to an accepted calculation method (QSAR) by Veith et al. 1979) and 51.75 (EpiSuite calculation using ver. 3.0 (US-EPA)), showing no risk for bioaccumulation based on the logKow/phys.-chem. properties. 


Further, the ester is rapidly hydrolysed by carboxylesterases to methacrylic acid (MAA) and the respective alcohol. Carboxylesterases are a group of enzymes with a broad/unspecific substrate spectra and are established for plants, animals and a variety of microorganisms.For further information on the metabolism see chaptor 7.1 'Toxicokinetics, metabolism and distribution'. This is also demonstrated in the readily biodegradability of the substance and its metabolites (see section readily biodegradability). 


 


The low exposure, low logKow, readily biodegradability and rapid metabolization within an organism are enough to show, that the bioaccumulation study is not necessary.


Lastly, as the substance is readily biodegradable the bioaccumulation study is not needed to conclude the PBT/vPvB-assessment.




Key value for chemical safety assessment

Additional information