Registration Dossier

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

For the assessment of the skin sensitising potential of Triethylenglycoldivinylether a Guinea Pig Maximization test was performed with 20 albino guinea pigs according to OECD 406 (GLP guideline study; Huntingdon 1987). The test substance produced evidence of delayed contact hypersensitivity in four animals. There was no evidence of delayed contact hypersensitivity in sixteen animals. A positive skin response in at least 30% of the animals in an adjuvant test should be expected for mild/moderate sensitisers. In this study a positive result was only observed in 20 % of the animals, therefore the test substance was considered not to be sensitising.


Migrated from Short description of key information:
GPMT (OECD 406): not sensitising

Justification for classification or non-classification

Classification is not warranted according to the criteria of EU Directive 67/548/EEC and EU Classification, Labelling and Packaging of Substances and Mixtures (CLP) Regulation (EC) No. 1272/2008.