Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 926-571-4 | CAS number: 1187203-96-8
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: secondary literature: OECD SIDS published by UNEP (review)
Data source
Reference
- Reference Type:
- publication
- Title:
- Diphenyl carbonate, CAS-No. 102-09-0; SIDS Initial Assessment Report for SIAM 19, 2004-10-19-22
- Author:
- OECD SIDS
- Year:
- 2 004
- Bibliographic source:
- OECD SIDS documents (Chemicals Screening Information Dataset for High Volume Chemicals) published by UNEP in 2006
Materials and methods
- Principles of method if other than guideline:
- review
Test material
- Reference substance name:
- Diphenyl carbonate
- EC Number:
- 203-005-8
- EC Name:
- Diphenyl carbonate
- Cas Number:
- 102-09-0
- Molecular formula:
- C13H10O3
- IUPAC Name:
- diphenyl carbonate
Constituent 1
Results and discussion
Applicant's summary and conclusion
- Interpretation of results:
- harmful
- Remarks:
- Migrated information
- Conclusions:
- LD 50 harmful
- Executive summary:
The acute oral LD50 of diphenyl carbonate was 1500 mg/kg bw in rats, with clonic convulsions as main clinical sign appearing at doses near to or exceeding the LD50 value (OECD TG 401) (OECD SIDS published by UNEP, 2006).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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