Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Additional information

The key study (Thompson, 2002) was conducted according to GLP and standardised guidelines with a sufficient level of detail to assess the quality of the study. Salmonella typhimurium (strains; TA100, TA1537, TA 1535 and TA98) and Escherichia coli (strain: WP2uvrA) were exposed to concentration of the test material ranging from 15 – 5000 µg/plate in the presence and absence of metabolic activator S9-mix. The test material gave a negative response with none of the assays showing a significant change in revertant colony numbers and is said to be non-mutagenic. The study was performed to a good standard and was assigned a reliability score of 1 using the principles for assessing data quality as set out in Klimisch (1997).

Short description of key information:
The genetic toxicity of 1-bromohexadecane was determined to be negative according to a study performed in line with standardised guidelines OECD 471, EU Method B13/14 and EPA OPPTS 870.5100 harmonised guidelines.

Endpoint Conclusion: No adverse effect observed (negative)

Justification for classification or non-classification

The genetic toxicity study indicates that the test material has no effect which requires classification. Therefore the material does not require classification under Regulation EC 1272/2008.