Registration Dossier

Administrative data

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
18 Sep 2014 - 25 Sep 2014
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: The study was done in accord with EU guidance and was in compliance with GLP criteria.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2014
Report date:
2014

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7950 (Vapor Pressure)
Deviations:
no
GLP compliance:
yes
Type of method:
effusion method: by loss of weight or by trapping vaporisate

Test material

Constituent 1
Reference substance name:
Laurylimidazole
IUPAC Name:
Laurylimidazole
Test material form:
other: Liquid
Details on test material:
- Name of test material (as cited in study report): MTDID 13999
- Analytical purity: 99.0%
- Storage condition of test material: At room temperature in the dark

Results and discussion

Vapour pressure
Temp.:
20 °C
Vapour pressure:
0.009 Pa

Applicant's summary and conclusion

Conclusions:
The vapor pressure of laurylimidazole is 0.0088 Pa at 20°C.
Executive summary:

The vapor pressure of the test substance was determined by the isothermal thermogravimetric effusion method. The weight loss of the sample was measured at 4 isothermal points between 90 and 120°C. Weight loss rate at each temperature was converted to vapor pressure and entered into linear regression analysis vs. temperature. The resulting equation was log P(T) = -4327 ×1/T + 12.70 (r = 0.9994). The test was done according to EU Method A.4 “Vapour pressure” and OECD 104 “Vapour Pressure Curve” and in accord with GLP guidelines, and the thermogravimetric analysis method is particularly suited to substances of low vapor pressure (10E-10 Pa to 1 Pa). Therefore this study is classified as reliable without restriction.