Registration Dossier

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Additional information

Short description of key information:
- Ames test: negative
- in vitro UDS assay: negative (2 studies, read across to Ethylene glycol dimethyl ether and Diethylene glycol dimethyl ether)
- in vitro gene mutation assay: negative (read across to Ethylene glycol dimethyl ether)
- in vivo micronucleus test in mice: negative (read across to Ethylene glycol dimethyl ether)
- in vivo Chromosome Aberration study : negative ( 2 studies, read across to Ethylene glycol dimethyl ether and Diethylene glycol dimethyl ether)


Endpoint Conclusion: No adverse effect observed (negative)

Justification for classification or non-classification

It can be concluded from the data available for Triethylene glycol dimethyl ether and its structural analogues Ethylene glycol dimethyl ether and Diethylene glycol dimethyl ether that mutagenicity and genotoxicity are not caused by Triethylene glycol dimethyl ether and therefore classification for this end point is not warranted.