Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

A 29 day oral toxicity study was performed in rats. The animals were exposed to 0, 62.5, 250 and 1000 mg/kg bw/d. At 1000 mg/kg/d, males exhibited decreased testes and epididymides that correlated with microscopical indications of impaired spermatogenesis.

Key value for chemical safety assessment

Repeated dose toxicity: via oral route - systemic effects

Endpoint conclusion
Dose descriptor:
250 mg/kg bw/day
Study duration:

Additional information



Justification for classification or non-classification

The repeated dose toxicity of Triethylene glycol dimethyl ether was investigated according to OECD 407. NOAEL of 250 mg/kg/d was obtained. No classification with respect to the endpoint repeated dose toxicity is justified.