Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Does not significantly accumulate in aquatic organisms.

Additional information

The bioaccumulative potential of CAS 41484-35-9 was assessed in a weight-of-evidence approach taking into account different QSAR calculations and further molecular parameters. It can be expected that the parent compound does not accumulate in organisms. The main metabolite (CAS 20170 -32 -5) was also assessed. Its calculated BCF was 13.2 L/kg. The prediction was conducted with the neutral molecule. As the compound has a pKa of 4.77 it is present mosly in its anionic form under environmental conditons. The logD ranges from 3.8 at pH 5 to 0.2 at pH 9 which is well below the B screening criterion of 4.5. Due to these results it can be assumed that the main metabolite CAS 20170 -32 -5 is not bioaccumulative either.

In conclusion, the results indicate that siginficant accumulation in aquatic organisms is not to be expected. Furthermore, the substance is clearly failing the B cut-off criterion for BCF of 2000.