Registration Dossier

Diss Factsheets

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information

Bioaccumulation test on aquatic species is waived based on the fact that the available information (log Kow and calculated BCF values) is deemed sufficient for the PBT assessment, classification and labelling and the chemical safety assessment. The BCFs for aquatic and terrestrial organisms were calculated using QSARs of Veith et al. (1979) and Jager (1998), both incorporated in the EUSES model, and yielded values of 1100 and 302 L/kg ww, respectively. However, it can be anticipated that simple esters, such as acetic esters, will be converted to the respective alcohols by carboxylesterases in fish liver and therefore the BCF values calculated are considered worst case values.