Registration Dossier
Registration Dossier
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EC number: 266-357-1 | CAS number: 66422-95-5
Endpoint summary
Administrative data
Description of key information
Hydrolysis
Following the preliminary test OECD 111 (5 days incubation at 50°C at pH values 4, 7 and 9), it was not possible to determine the hydrolysis due to a non-hydrolytic decomposition of the test item (change of colour, likely an oxidative process).
Biodegradation
Three GLP tests were conducted on the test substance. Two following the OECD 301B guideline and one following the OECD 302B guideline.
In the OECD 301B test, the test item was tested using a concentration of nominally 10 and 12 mg organic carbon/L in test medium. Functional and toxicity controls were used. All validity criteria were met. The biodegradation of the test item showed that the mean 10% level (beginning of the biodegradation) was not reached until test end. The mean biodegradation remained in the range 0 -1% until test end. Under the test conditions the test item is classified as not readily biodegradable in the 10-day-window and within 28 days.
In the OECD 302B test, the test item was tested using a concentration of nominal 200 mg organic carbon/L (500.7 mg/L of test substance). To measure the degradation of test item and positive control, the content of dissolved organic carbon (DOC) in the test vessels was measured 12 times during the test. All validity criteria were met. Degradation of the positive control was 99 % after 5 days. The degree of biodegradation reached 84 % after 28 days. Both test replicates showed very good correlation of the degradation parameters. After 6 days 70 % was reached. The degradation in the toxicity flask was 89 % at the end of the test. The test item can be stated as “not toxic towards the inoculum in a concentration of 500.7 mg/L”. Abiotic degradation reached 30 % at the end of the test. DOC elimination in the adsorption control was based by on adsorption of the test item onto the inoculum or on other abiotic processes (as for example precipitation resulting from reaction with HgCl2). That means DOC elimination in the test vessels might be also caused by adsorption or precipitation effects and not only by biodegradation. DOC elimination in the test replicates was higher than in the adsorption control until day 14. This should indicate that DOC elimination was partly caused by biodegradation.
Adsorption/desorption
The adsorption coefficient Koc and log Koc of the test item were estimated according to EU test method C19. Log Koc was < 1.25 and Koc was <17.8.
e test conditions the test item is classified as not readily biodegradable in the 10-day-window and within 28 days.
Additional information
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