Ethene, homopolymer, oxidized, hydrolyzed, distn. residues, from C16-18 alcs. manuf.

Repeated dose toxicity: other routes

Administrative data

Endpoint:

repeated dose toxicity: other route

Type of information:

migrated information: read-across based on grouping of substances (category approach)

Adequacy of study:

supporting study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: The studies on which the conclusion is based are comparable to guideline studies or publications with sufficient detail for assessment.

Data source

Reference

Reference 1

Reference Type:

secondary source

Title:

SIDS Dossier - Octadecanol, 1995 with additional robust summaries for studies for key end points provided by consortium members, prepared in support of the Aliphatic Alcohols category

Author:

Global ICCA Aliphatic alcohols Consortium

Year:

2005

Reference 2

Reference Type:

secondary source

Title:

Health effects SIAR for Long Chain Alcohols (C6-22) including Iuclid dossiers chapter 5 prepared for the Aliphatic Alcohols category

Author:

Veenstra G, Webb C

Year:

2005

Materials and methods

Test material

Test material information

Constituent 1

Reference substance name:

Icosan-1-ol

EC Number:

211-119-4

EC Name:

Icosan-1-ol

Cas Number:

629-96-9

Molecular formula:

C20H42O

IUPAC Name:

icosan-1-ol

Details on test material:

as prescribed by 1.1 - 1.4

Results and discussion

Target system / organ toxicity

Critical effects observed:

not specified

Applicant's summary and conclusion

Conclusions:

Expected to be of low systemic toxicity on repeated exposure.