Registration Dossier
Registration Dossier
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EC number: 909-068-4 | CAS number: -
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Study period:
- June 2000
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 000
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 404 (Acute Dermal Irritation / Corrosion)
- Qualifier:
- according to guideline
- Guideline:
- EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion)
- GLP compliance:
- yes
Test material
- Reference substance name:
- Reaction mass 2-methylpenta-1,3-diene and 4-methylpenta-1,3-diene
- EC Number:
- 909-068-4
- Molecular formula:
- C6H10
- IUPAC Name:
- Reaction mass 2-methylpenta-1,3-diene and 4-methylpenta-1,3-diene
- Test material form:
- other: liquid
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- New Zealand White
Test system
- Type of coverage:
- semiocclusive
- Preparation of test site:
- other: intact skin
- Vehicle:
- unchanged (no vehicle)
- Duration of treatment / exposure:
- 4 hours, 0,5 mL
- Observation period:
- 1, 14, 48, 72 hours and 7 and 14 days.
- Number of animals:
- 3 rabbits
Results and discussion
In vivo
Results
- Irritation parameter:
- primary dermal irritation index (PDII)
- Score:
- 3.2
Applicant's summary and conclusion
- Interpretation of results:
- moderately irritating
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- The test material did not meet the criteria for classification as irritant or corrosive according to EU labelling regulations Cimmission Directive 93/21/EEC.
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