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EC number: 209-676-3 | CAS number: 590-28-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1959
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study with acceptable restrictions
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- No guideline indicated. Principles of method see below.
- GLP compliance:
- not specified
- Analytical monitoring:
- not specified
- Details on sampling:
- not indicated.
- Vehicle:
- no
- Details on test solutions:
- Waste water supplemented with 570 mg/L KNO3, 200 mg/L CaSO4, 140 mg/L KH3PO4, 90 mg/L MgSO4 and 3 mg/L FeCl3
- Test organisms (species):
- Scenedesmus sp.
- Details on test organisms:
- not indicated.
- Test type:
- static
- Water media type:
- freshwater
- Total exposure duration:
- 96 h
- Post exposure observation period:
- no post exposure period
- Hardness:
- 12°dGH
- Test temperature:
- 24 °C
- pH:
- 7.5
- Dissolved oxygen:
- not indicated.
- Salinity:
- not indicated.
- Nominal and measured concentrations:
- not indicated.
- Details on test conditions:
- not indicated.
- Reference substance (positive control):
- yes
- Remarks:
- known water pollutants were measured in parallel
- Key result
- Duration:
- 96 h
- Dose descriptor:
- LOEC
- Effect conc.:
- 520 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Details on results:
- not indicated.
- Results with reference substance (positive control):
- not indicated.
- Reported statistics and error estimates:
- not indicated.
- Validity criteria fulfilled:
- not specified
- Conclusions:
- Potassium cyanate showed toxicity on growth of Scenedesmus sp. from a concentration of from 520 mg/L on.
- Executive summary:
In a 96 hour acute toxicity study, the cultures of Scenedesmus sp. were exposed to potassium cyanate under static conditions. Potassium cyanate showed a distinct toxicity on growth of Scenedesmus sp. from a concentration of 520 mg/L on (LOEC = 520 mg/L). This toxicity study is classified as acceptable as key study.
Results Synopsis:
Test Organism: Scenedesmus sp.
Test Type: Static
LOEC = 520 mg/L
Reference
Description of key information
For potassium cyanate, a non-standard study (key) is available. The LOEC identified was 520 mg/L in Scenedesmus sp. In a read-across study (supporting) with the structural analogue sodium cyanate, which was conducted recently according to OECD and EU Guidelines and GLP, a LC50 of >100 mg/L, equivalent to > 125 mgL of potassium cyanate, was determined in a limit study in Desmodesmus subspicatus.
Key value for chemical safety assessment
- EC10 or NOEC for freshwater algae:
- 520 mg/L
Additional information
Key Study:
In a 96 hour acute toxicity study, the cultures of Scenedesmus sp. were exposed to potassium cyanate under static conditions. Potassium cyanate showed a distinct toxicity on growth of Scenedesmus sp. from a concentration of 520 mg/L on (LOEC = 520 mg/L).
Supporting study:
The study (LAUS, 2009) was performed using one concentration containing 100 mg/L. The treatments were used to incubate the unicellular freshwater green alga Desmodesmus subspicatus for a period of 72 hours. The cell concentration of each replicate was determined by measuring the absorption of the cuvettes at 440 nm every 24 hours with a spectral photometer. With these measured values, the number of cells was calculated (linear correlation be-tween cell concentration and absorption given). Then the growth rate µ, the area under the growth curve (AUC ) and the Yield were determined.
At the beginning and at the end of the test, the content of the test item in the test solution was determined using a spectral photometer. The recovery after 72 hours was 109 % of the start concentration. The correlation between nominal and measured concentration was good (98% at the beginning.and.107 % at the end). Therefore, the determination of the biological results was based on nominal concentration.
The EC50s of potassium dichromate were tested in a current positive control test. The values lay within the normal range of the laboratory.
The following results for the test item sodium cyanate were determined:
Endpoint |
NOEC |
LOEC |
EC50 |
Growth Rate |
100 mg/L |
>100 mg/L |
>100 mg/L |
AUC |
100 mg/L |
>100 mg/L |
>100 mg/L |
Yield |
100 mg/L |
>100 mg/L |
>100 mg/L |
The NOEC value of 100 mg/L for sodium cyanate corresponds to a value of 125 mg/L potassium cyanate and supports the LOEC value of > 520 mg/L as described in the key study.
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