Registration Dossier
Registration Dossier
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EC number: 309-629-8 | CAS number: 100545-48-0
Particle size distribution (Granulometry)
Administrative data
Link to relevant study record(s)
Description of key information
Under the test conditions, the particle size distribution of the tested reference batch of the substance was found to be :
- proportion of the tested sample having an inhalable particle size <100 µm equal to 94%
- proportion of the tested sample having a thoracic particle size <10.0 µm equal to 1.77%
- proportion of the tested sample having a respirable particle size <5.5 µm equal to 0.255%.
Too few particles were of a size less than 10.0 µm to allow accurate assessment of the mass median aerodynamic diameter.
Additional information
A study was performed to determine the partition size distribution of the test substance according to OECD Guideline 110. The test was performed using a Marple Miller Cascade Impactor. Sampling for the cascade impactor determinations was performed by rolling the test substance container for approximately 10 minutes then taking samples from the top, middle and bottom (Fox and White, 2012).
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