Registration Dossier
Registration Dossier
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EC number: 231-472-8 | CAS number: 7575-23-7
Endpoint summary
Administrative data
Description of key information
There is sufficient information from experience in humans that PETMP is a skin sensitizer. This is corroborated by older guinea pig data.
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (sensitising)
- Additional information:
In clinical case reports in humans the sensitising property of PETMP has been demonstrated in occupational populations working regularly with the compound.
PETMP was identified as the sensitizing component in the Letterflex urethane photoprepolymer mixture (Malten, 1977a).
PETMP and 3-MPA were identified as sensitizing components in the Letterflex urethane photoprepolymer mixture (Malten, 1977b).
PETMP was confirmed as a strong sensitizing component in the Letterflex mixture in a GPMT (Calas, 1977).
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
- Additional information:
Regarding respiratory sensitisation, no evaluated testing procedures are available. Testing of the endpoint is not required according to REACh.
Justification for classification or non-classification
Based on sufficient human data on allergy cases and a high sensitisation rate in guinea pigs. Therefore, PETMP will be classified as Skin Sens. 1A. H317. May cause an allergic skin reaction.
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