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Toxicological information

Acute Toxicity: inhalation

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Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
disregarded due to major methodological deficiencies
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: secondary references

Data source

Materials and methods

Results and discussion

Effect levels
Remarks on result:
other: see Any Other Information

Any other information on results incl. tables

Acute inhalation

Data lacking

No valid studies are available. The available study gets a K4 since no original references are available only secondary references. No LD50 is available.

 

Classification and Labeling

No LD50 available, data is not sufficient for C&L purposes.

No deaths after 8 hour exposure to saturated vapor.

Union carbide corp. unpublished data. Cited in[Clayton, G. D. and F. E. Clayton (eds.). Patty's Industrial Hygiene and Toxicology: Volume 2A, 2B, 2C: Toxicology. 3rd ed. New York: John Wiley Sons, 1981-1982., p. 4687]

Narcosis, but not death, was observed in mice inhaling concentrations close to saturation.

The threshold for an irritating effect in man was 220 mg/m3.

 

Bukhalovskii, A. A. & Shugaev, B. B. (1976). Toksichnost i gigienicheskoe normirovanie izoforona, digidroizoforona

i dimetilfenilkarbinola.Promyshlennost Sillleticheskogo Kauchuka1976 (2), 4. Cited in:Food and Chemical Toxicology. Vol. 20, Pg. 675, 1982

Applicant's summary and conclusion

Interpretation of results:
study cannot be used for classification
Conclusions:
No valid studies are available. The available study gets a K4 since no original references are available only secondary references. No LD50 is available, data is not sufficient for C&L purposes.
Executive summary:

No valid studies are available. The available study gets a K4 since no original references are available only secondary references. No LD50 is available, data is not sufficient for C&L purposes.