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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 931-125-7 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://www.echa.europa.eu/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_ecotoxicological-information.png)
Toxicity to microorganisms
Administrative data
- Endpoint:
- toxicity to microorganisms
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Study period:
- 1991-08-09
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: GLP guideline study, tested with the source substance CAS 1318-02-1. According to the ECHA Guidance Document "Practical guide 6: How to report read-across and categories (March 2010)", the reliability was changed from RL1 to RL2.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 992
- Report date:
- 1992
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- DIN 38412-8 (Pseudomonas Zellvermehrungshemmtest)
- Deviations:
- no
- GLP compliance:
- yes
Test material
- Reference substance name:
- Automatically generated during migration to IUCLID 6, no data available
- IUPAC Name:
- Automatically generated during migration to IUCLID 6, no data available
- Details on test material:
- - Name of test material (as cited in study report): Wessalith P
- Related CAS number: 1318-02-1
- Chemical name: Natriumaluminiumsilikat
- Framework: monoclinic
- Physical state: white crystalline powder
- Analytical purity: 80.6% active ingredient, 19.4% crystal water (source TNO), 79.8% active ingredient (source Degussa), respectively - two information sheets are given in the study report
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test solutions
- Vehicle:
- no
- Details on test solutions:
- As the test substance contained water insoluble particles, the centrifuged supernatants of each concentration were used for testing.
Test organisms
- Test organisms (species):
- Pseudomonas putida
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 16 h
Test conditions
- Hardness:
- no data
- Test temperature:
- 21+/-0.5 °C
- pH:
- pH in the control at test start was 7.1, at test end 6.9 to 7.4 for neutralized background samples, and 7.1 to 10.2 for alkaline background samples, increasing with concentration.
- Dissolved oxygen:
- no data
- Nominal and measured concentrations:
- 0, 0.1, 0.3, 0.10, 0.33, 1.0, 3.3, 5.5 and 10 g/L of the test substance
- Reference substance (positive control):
- no
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 16 h
- Dose descriptor:
- EC10
- Effect conc.:
- 330 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Remarks:
- eluate
- Basis for effect:
- growth inhibition
- Duration:
- 16 h
- Dose descriptor:
- EC50
- Effect conc.:
- 950 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Remarks:
- eluate
- Basis for effect:
- growth inhibition
- Duration:
- 16 h
- Dose descriptor:
- EC50
- Effect conc.:
- 1 550 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Remarks:
- eluate
- Basis for effect:
- growth inhibition
- Remarks on result:
- other: alkalic
Any other information on results incl. tables
The EC10 was
estimated to 0.33 g/L for both samples. The EC50 value for neutralized
samples was found to correspond to 0.95 g/L (95% confidence interval of
0.57-1.59 g/L), for alkaline samples 1.55 g/L (95% confidence interval
of 0.53-4.54 g/L).
The bacterial growth generally resulted in a decrease of the pH of the
medium. The highest decrease was found with a neutralized test substance
(0.33 g/L, pH 4.9). The inhibition was also stronger after
neutralization, indicating that at least a part of the inhibition was
caused by this decrease.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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