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EC number: 270-298-7
CAS number: 68424-37-3
data set for the category member Fatty Acids regards biodegradation
includes standard biodegradation studies as well as data obtained by
QSAR. As summarized in the category justification, the member of the
fatty acid category demonstrates ready biodegradability. The vast
majority of the experimental results revealed ready biodegradability
which was supported by reliable QSAR predictions. In some cases
insufficient sampling points were available to determine whether or not
the 10-day window was met. Studies in which the 10-day window was not
met likely did not ensure that the fatty acids tested were fully in
solution. According to the ECHAs Guidance on information requirements
and chemical safety assessment (Chapter R.7b: Endpoint specific
guidance, 2008) the screening tests on ready biodegradation sometimes
fail because of the stringent test conditions, in general, and the
differences among the individual tests in terms of their stringency.
Therefore, consistent positive test results should generally supersede
negative results. In conclusion, aliphatic fatty acids comprising C8-C22
carbon chain length are judged to be readily biodegradable. This
judgment is consistent with the hazard assessment presented in the OECD
SIDS (2009) for the category “Aliphatic Acids Category” where aliphatic
fatty acids with a carbon chain length in the range of C8 – C22 also
were judged to be readily biodegradable.
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