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Diss Factsheets
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EC number: 223-772-2 | CAS number: 4065-45-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- long-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Data is from peer reviewed journal
- Justification for type of information:
- Data is from peer reviewed journal
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 211 (Daphnia magna Reproduction Test)
- Principles of method if other than guideline:
- 21 d reproduction study performed according to OECD guideline 211.
- GLP compliance:
- not specified
- Analytical monitoring:
- not specified
- Vehicle:
- not specified
- Test organisms (species):
- Daphnia magna
- Test type:
- not specified
- Water media type:
- freshwater
- Total exposure duration:
- 21 d
- Nominal and measured concentrations:
- five concentrations ranging between 0.128–5 mg/L
- Details on test conditions:
- Renewal of medium took place every 48 h, and the offsprings produced by each parent animal were counted daily.
- Duration:
- 21 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 0.128 - 5 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- test mat.
- Basis for effect:
- reproduction
- Details on results:
- No adverse effects on either the number or sex of offsprings,or body size were observed after exposure to five concentrations of the test substance (0.128–5 mg/L).
- Conclusions:
- Long term toxicity (21 d) value of test material to Daphnia magna resulted in a no observed effect concentration ( NOEC) ranging between 0.128–5 mg/L.
- Executive summary:
21 d reproduction study performed according to OECD guideline 211. Renewal of medium took place every 48 h, and the offsprings produced by each parent animal were counted daily. The exposure concentration was in the range of a tenth of the acute toxicity value. No adverse effects on either the number or sex of offsprings, or body size were observed after exposure to five concentrations each .Long term toxicity (21 d) value of sulisobenzone (benzophenone-4) to Daphnia magna resulted in a no observed effect concentration ( NOEC) ranging between 0.128–5 mg/L. Based on the above effect concentration it is considered to be non - hazardous to aquatic environment and can not be classified as per CLP criteria .
Reference
Description of key information
Long term toxicity to aquatic invertebrate:
21 d reproduction study performed according to OECD guideline 211. Renewal of medium took place every 48 h, and the offsprings produced by each parent animal were counted daily. The exposure concentration was in the range of a tenth of the acute toxicity value. No adverse effects on either the number or sex of offsprings, or body size were observed after exposure to five concentrations each .Long term toxicity (21 d) value of sulisobenzone (benzophenone-4) to Daphnia magna resulted in a no observed effect concentration ( NOEC) ranging between 0.128–5 mg/L. Based on the above effect concentration it is considered to be non - hazardous to aquatic environment and can not be classified as per CLP criteria .
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 5 mg/L
Additional information
Long term toxicity to aquatic invertebrate:
21 d reproduction study performed according to OECD guideline 211. Renewal of medium took place every 48 h, and the offsprings produced by each parent animal were counted daily. The exposure concentration was in the range of a tenth of the acute toxicity value. No adverse effects on either the number or sex of offsprings, or body size were observed after exposure to five concentrations each .Long term toxicity (21 d) value of sulisobenzone (benzophenone-4) to Daphnia magna resulted in a no observed effect concentration ( NOEC) ranging between 0.128–5 mg/L. Based on the above effect concentration it is considered to be non - hazardous to aquatic environment and can not be classified as per CLP criteria .
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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