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Physical & Chemical properties

Density

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Reference
Endpoint:
density, other
Remarks:
density
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Justification for type of information:
Experimental tests performed using standard test guidelines
Qualifier:
according to guideline
Guideline:
OECD Guideline 109 (Density of Liquids and Solids)
Qualifier:
according to guideline
Guideline:
other: method recommended in the International Pharmacopoeia, fourth Edition, 2014.
GLP compliance:
no
Type of method:
pour and tap (for solids)
Key result
Type:
pour density
Density:
0.298 g/cm³
Temp.:
20 °C
Remarks on result:
other: pressure - 973.4 hPa
Key result
Type:
tap density
Density:
0.315 g/cm³
Temp.:
20 °C
Remarks on result:
other: pressure - 973.4 hPa
 Parameters  Details  Calculated values      Average Density

 

  1st Calculation  2nd Calculation   

Pour Density of test Item  (g/cm³)

  = m/V

  0.3086

 0.2868

 0.2977

Tap density of test Item (g/cm³)

= m V1 

0.3268 

0.3036

0.3152

Conclusions:
The mean pour density and tapped density of test chemical was determined to be 0.2977 g/cm³ and 0.3152 g/cm³at 20°C and 973.4 hPa.
Executive summary:

The density of test chemical was determined following OECD guideline 109 and according to the method recommended in the

International Pharmacopoeia, fourth Edition, 2014. The mean pour density and tapped density of the test item was determined to be 0.2977 g/cm³ and 0.3152 g/cm³at 20°C and 973.4 hPa.

Description of key information

The density of test chemical was determined following OECD guideline 109 and according to the method recommended in the

International Pharmacopoeia, fourth Edition, 2014. The mean pour density and tapped density of the test item was determined to be 0.2977 g/cm³ and 0.3152 g/cm³at 20°C and 973.4 hPa.

Key value for chemical safety assessment

Relative density at 20C:
0.298

Additional information

The density of test chemical was determined following OECD guideline 109 and according to the method recommended in the

International Pharmacopoeia, fourth Edition, 2014. The mean pour density and tapped density of the test item was determined to be 0.2977 g/cm³ and 0.3152 g/cm³at 20°C and 973.4 hPa.

From other experimental report,bulk density of test chemical was determined to be 0.587 g/cm3 at 22degC.