Registration Dossier

Classification & Labelling & PBT assessment

DSD-DPD

General information

Name:
Reaction product of 2,4/ 2,6 TDI (m-tolylidene diisocyanate, CAS 26471-62-5) in excess and m-TDA (diaminotoluene, CAS 25376-45-8) forming Biuret structures via non-isolated polyurea intermediates
Status:
67/548/EEC self classification
Remarks:
According to Regulation (EC) No 67/548/EEC the classification of 2,4-/2,6-TDI (CAS No 26471-62-5, Index No 615-006-00-4) was considered for the classification of the present substance since it contains >= 50 % of 2,4-/2,6-TDI with one exception: The present substance has to be classified as Irritant, Risk of serious damage to eyes (Xi, R41)

Classification

Explosiveness

Reason for no classification:
data conclusive but not sufficient for classification

Oxidising properties

Reason for no classification:
data conclusive but not sufficient for classification

Flammability

Reason for no classification:
data conclusive but not sufficient for classification

Thermal stability

Reason for no classification:
data conclusive but not sufficient for classification

Acute toxicity

Classification:
T+; R26 Very toxic by inhalation.

Acute toxicity - irreversible damage after single exposure

Reason for no classification:
data conclusive but not sufficient for classification

Repeated dose toxicity

Reason for no classification:
data conclusive but not sufficient for classification

Irritation / corrosion

Classification:
Xi; R41 Risk of serious damage to eyes.

Sensitisation

Classification:
R42/43 May cause sensitisation by inhalation and skin contact.

Carcinogenicity

Classification:
Carc. Cat. 3; R40 Limited evidence of a carcinogenic effect.

Mutagenicity - genetic toxicity

Reason for no classification:
data conclusive but not sufficient for classification

Toxicity to reproduction - fertility

Reason for no classification:
data conclusive but not sufficient for classification

Toxicity to reproduction - development

Reason for no classification:
data conclusive but not sufficient for classification

Toxicity to reproduction - breastfed babies

Reason for no classification:
data conclusive but not sufficient for classification

Environment

Classification:
R52/53 Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment.

Labelling

Indication of danger

T+ - very toxic

Risk phrases

R26 - Very toxic by inhalation
R40 - Limited evidence of a carcinogenic effect
R41 - Risk of serious damage to eyes
R42/43 - May cause sensitisation by inhalation and skin contact
R52/53 - Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment

Safety phrases

S1/2 - keep locked up and out of reach of children
S23 - do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer)
S36/37 - wear suitable protective clothing and gloves
S45 - in case of accident or if you feel unwell, seek medical advice immediately (show the label where possible)
S61 - avoid release to the environment. refer to special instructions/safety data sheets

Specific concentration limits

1. Concentration range (%):
>= 0.1 - < 1
Classification:
Xn; R20 Harmful by inhalation.
R42 May cause sensitisation by inhalation.
2. Concentration range (%):
>= 1 - < 7
Classification:
T; R23 Toxic by inhalation.
Carc. Cat. 3; R40 Limited evidence of a carcinogenic effect.
R42/43 May cause sensitisation by inhalation and skin contact.
3. Concentration range (%):
>= 7 - < 20
Classification:
T+; R26 Very toxic by inhalation.
Carc. Cat. 3; R40 Limited evidence of a carcinogenic effect.
R42/43 May cause sensitisation by inhalation and skin contact.
4. Concentration range (%):
>= 20 - < 25
Classification:
T+; R26 Very toxic by inhalation.
Carc. Cat. 3; R40 Limited evidence of a carcinogenic effect.
Xi; R41 Risk of serious damage to eyes.
R42/43 May cause sensitisation by inhalation and skin contact.
5. Concentration range (%):
>= 25
Classification:
T+; R26 Very toxic by inhalation.
Carc. Cat. 3; R40 Limited evidence of a carcinogenic effect.
Xi; R41 Risk of serious damage to eyes.
R42/43 May cause sensitisation by inhalation and skin contact.
R52/53 Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment.

Notes