Reaction mass of 1,3-dioxane-5,5-dimethanol and 1,3-Propanediol, 2-(hydroxymethyl)-2-[(methoxymethoxy)methyl]-

Long-term toxicity to aquatic invertebrates

Link to relevant study record(s)

Reference

Endpoint:

long-term toxicity to aquatic invertebrates

Type of information:

experimental study planned

Justification for type of information:

CONSIDERATIONS THAT THE GENERAL ADAPTATION POSSIBILITIES OF ANNEX XI OF THE REACH REGULATION ARE NOT ADEQUATE TO GENERATE THE NECESSARY INFORMATION:

- No existing GLP studies study available for this endpoint.
- No existing non-GLP studies study available for this endpoint.
- No historical ecotoxicology data available for this endpoint.
- No existing (Q)SAR information can properly assess this endpoint.
- No sufficient information available that could fulfill the standard information requirement through the weight of evidence approach.
- No information from structurally similar substance can be used to fulfill the standard information requirement through grouping and read-across.

CONSIDERATIONS THAT THE SPECIFIC ADAPTATION POSSIBILITIES OF ANNEXES VI TO X (AND COLUMN 2 THEREOF) OF THE REACH REGULATION ARE NOT ADEQUATE TO GENERATE THE NECESSARY INFORMATION:
- Chronic Daphnia magna Reproduction Test design is the standard information requirement for substance registered for 100 tonnes or more per year (Annex IX, Section 9.1.5., column 1, of the REACH Regulation).

Qualifier:

according to guideline

Guideline:

OECD Guideline 211 (Daphnia magna Reproduction Test)

Description of key information

In accordance with REACH Regulation (EC) No. 1907/206, Annex IX, Section 9.1.5. Long-term toxicity testing on invertebrates is proposed for the aquatic invertebrate endpoints in order to assess aquatic toxicity.