Registration Dossier
Registration Dossier
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EC number: 200-908-9 | CAS number: 75-85-4
Endpoint summary
Administrative data
Description of key information
Additional information
The substance is tested to be moderately biodegradable but well eliminable from the aquatic environment after prolonged exposure. Due to a degree of total mineralization (CO2 evolution) of 50 -60% after 42 days of exposure it can be assumed that the substance is not persistent in the aquatic environment.
In addition, the available experimental biodegradation data was supported by (Q)SAR calculation; the substance was within the applicability domain of the applied estimation model (BASF SE 2018): The model CATALOGIC 301B (OASIS Catalogic v5.12.1) calculated biodegradation of CAS 75 -85 -4 to be 86.5% after 28 days, based on CO2-Evolution.
Metabolite predition:
The model Catalogic 301 B v02.09 (OASIS Catalogic v5.12.1) calculated 19 metabolites (for details see 'attached background material' of the respective Endpoint Study Record) identifying 3 metabolites as relevant degradation products in terms of PBT/vPvB assessment, with an estimated quantity of≥ 0.1%.All of the 3 metabolites identified as relevant degradation products were calculated to be readily biodegradable.Additionally, experimental data for the three metabolites also indicate ready biodegradability.
Therefore, no further testing is necessary because biodegradation is already tested suffieciently and further testing in this won't reveal any further helpful information.
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