Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 295-551-9 | CAS number: 92062-36-7
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
A skin sensitization study performed according to Magnusson and Kligman Guinea-Pig Maximization test (OECD TG 406) found no indication of skin sensitization in guinea pigs for Hydrocarbons, C9 aromatics. Hydrocarbons, C9 aromatics are not skin sensitizers or photosensitizers in humans. Hydrocarbons, C9 Aromatics were evaluated for its ability to induce skin sensitization in a 26 person Human Repeated Insult Patch Test (HRIPT). In addition, the ability to induce a phototoxic or photocontact response was determined by comparing irradiated and non-irradiated skin sites. Application to the skin without or in conjunction with UV irradiation did not elicit a sensitizing or photosensitizing response in any of the study participants.
Migrated from Short description of key information:
Hydrocarbons, C9 Aromatics were negative using a Magnusson and Kligman Guinea-Pig Maximization test (OECD TG 406). Hydrocarbons, C9 Aromatics were negative in a Human Repeated Insult Patch Test (HRIPT).
Respiratory sensitisation
Endpoint conclusion
- Additional information:
There are no reports of respiratory sensitization from C9 Aromatics in laboratory animals or humans. A skin sensitization study utilizing C9 Aromatics found no indication of skin sensitization in guinea pigs. Additional studies in humans also found no indication of skin sensitization. With these observations, it is presumed that C9 Aromatics will not be a respiratory sensitizing agent.
Migrated from Short description of key information:
no data
Justification for classification or non-classification
These findings do not warrant the classification of C9 Aromatic hydrocarbon solvents as a skin or respiratory sensitizer under the new Regulation (EC) 1272/2008 on classification, labeling and packaging of substances and mixtures (CLP) or under the Directive 67/518/EEC for dangerous substances and Directive 1999/45/EC for preparations.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
