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Sediment toxicity

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Description of key information

This endpoint is completed using read across from polysulfides, di-tert-dodecyl.

The NOEC for emergence rate was 741 mg/kg dw, and for development rate was 385 mg/kg dw. The EC10 values for both emergence and development rate were >741 mg/kg dw.

Key value for chemical safety assessment

Additional information

This endpoint is completed using read across from polysulfides, di-tert-dodecyl. For further information please see the read across justification attached in the IUCLID robust study summary.

Desmares-Koopmans (2017) is a study following OECD guideline 218, with Chironomus riparius. Sediment was spiked with test item at nominal concentrations of 100, 180, 320, 560 and 1000 mg/kg dw (mean measured concentrations 69, 125, 224, 385 and 741 mg/kg dw), with acetone used as a solvent. The test concentrations were determined based on results from a range-finding study and measured concentrations in sediment, porewater and overlying water were determined by UPLC-MS/MS at 0 and 28 days. A solvent control was also included, treated in the same way as the test item, as well as a blank control. Each replicate contained 85g wet sediment, made up of 12g spiked sand and 73g OECD medium. The ratio of overlying water: sediment was 4:1. 20 larvae were exposed per replicate, with four replicates for the control and each test concentration. After 28 days, NOEC and EC10 values were determined based on mean measured concentrations, based on statistically significant differences between the test item concentrations and the solvent control. The NOEC for emergence rate was 741 mg/kg dw, and for development rate was 385 mg/kg dw. The EC10 values for both emergence and development rate were >741 mg/kg dw. As the study follows a standard guideline, and all validity criteria were fulfilled, it is considered to be reliable without restrictions.