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Previous Testing Proposals

Previous Testing Proposals

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

 
3,3'-oxybis(ethyleneoxy)bis(propylamine) 224-207-2 4246-51-9
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
18/02/2021
18/02/2021
05/04/2021
05/04/2021
6-tert-butyl-2,4-xylenol 217-533-1 1879-09-0
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
18/02/2021
18/02/2021
05/04/2021
05/04/2021
Dimethyl(propyl)amine 213-139-9 926-63-6
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Ethyldimethylamine (EC 209-940-8)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Ethyldimethylamine (EC 209-940-8)
18/02/2021
18/02/2021
05/04/2021
05/04/2021
Hexyl salicylate 228-408-6 6259-76-3
Sub-chronic toxicity (90 day): oral
Reproductive toxicity (pre-natal developmental toxicity)
18/02/2021
18/02/2021
05/04/2021
05/04/2021
Reaction product of 2,4-Dinitrotoluene and 2,6-Dinitrotoluene and hydrogen 939-489-9 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
18/02/2021
18/02/2021
05/04/2021
05/04/2021
1-[(2-tert-butylcyclohexyl)oxy]butan-2-ol 412-300-2 - Reproductive toxicity (pre-natal developmental toxicity) 18/02/2021 05/04/2021
1-Propanone, 2-hydroxy-2-methyl-, 1-(4-C10-13-alkylphenyl) derivs. 600-033-6 1001416-18-7 Reproductive toxicity (pre-natal developmental toxicity) 18/02/2021 05/04/2021
2-Propenoic acid, 1,1'-[(1-methyl-1,2-ethanediyl)bis[oxy(methyl-2,1-ethanediyl)]] ester, reaction products with diethylamine 601-101-8 111497-86-0 Sub-chronic toxicity (90-day): oral 18/02/2021 05/04/2021
4-hydroxybenzophenone 214-507-1 1137-42-4 Genetic toxicity in vivo 18/02/2021 05/04/2021
Adipic acid 204-673-3 124-04-9 Reproductive toxicity (extended one-generation reproductive toxicity study) 18/02/2021 05/04/2021
Disodium 4-[4-[[5-[(2-bromo-1-oxoallyl)amino]-2-sulphonatophenyl]azo]-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl]-2,5-dichlorobenzenesulphonate 274-499-0 70247-70-0 Genetic toxicity in vivo 18/02/2021 05/04/2021
Disodium 6-amino-5-[[4-[(2-bromo-1-oxoallyl)amino]-2-[(4-methyl-3-sulphonatophenyl)sulphonyl]phenyl]azo]naphthalene-2-sulphonate 286-122-7 85187-33-3 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant 18/02/2021 05/04/2021
Disodium 6-amino-5-[[4-[(2-bromo-1-oxoallyl)amino]-2-sulphonatophenyl]azo]-4-hydroxynaphthalene-2-sulphonate 274-437-2 70210-40-1 Genetic toxicity in vivo 18/02/2021 05/04/2021
Fatty acids, C18-unsatd., dimers, oligomeric reaction products with 1-chloro-2,3-epoxypropane 500-215-4 68475-94-5 Genetic toxicity in vivo 18/02/2021 05/04/2021
m-xylene 203-576-3 108-38-3 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with p-xylene (EC 203-396-5) 18/02/2021 05/04/2021
p-xylene 203-396-5 106-42-3 Reproductive toxicity (extended one-generation reproductive toxicity study) 18/02/2021 05/04/2021
Reaction mass of propylidynetrimethanol and 2-ethylpropane-1,3-diol and 5-ethyl-1,3-dioxane-5-methanol 904-153-2 - Reproductive toxicity (extended one-generation reproductive toxicity study) 18/02/2021 05/04/2021
tert-butyl 3,5,5-trimethylperoxyhexanoate 236-050-7 13122-18-4 Genetic toxicity in vivo 18/02/2021 05/04/2021
Hexadecane 208-878-9 544-76-3
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
21/01/2021
21/01/2021
21/01/2021
08/03/2021
08/03/2021
08/03/2021
Hydrocarbons, C10-C13, aromatics, 922-153-0 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
21/01/2021
21/01/2021
21/01/2021
08/03/2021
08/03/2021
08/03/2021
Hydrocarbons, C10-C13, n-alkanes, isoalkanes, cyclics, aromatics (2-25%) 919-164-8 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
21/01/2021
21/01/2021
21/01/2021
08/03/2021
08/03/2021
08/03/2021
Hydrocarbons, C14-C19, isoalkanes, cyclics, <2% aromatics 920-114-2 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
21/01/2021
21/01/2021
21/01/2021
08/03/2021
08/03/2021
08/03/2021
Hydrocarbons, C16-C20, n-alkanes, isoalkanes, cyclics, aromatics (2-30 %) 919-006-8 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
21/01/2021
21/01/2021
21/01/2021
08/03/2021
08/03/2021
08/03/2021
Hydrocarbons, C7-C9, isoalkanes 921-728-3 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
21/01/2021
21/01/2021
21/01/2021
08/03/2021
08/03/2021
08/03/2021
Hydrocarbons, C9-C10, aromatics, >1% naphthalene 946-365-8 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
21/01/2021
21/01/2021
21/01/2021
08/03/2021
08/03/2021
08/03/2021
Hydrocarbons, C9-C11, isoalkanes, cyclics 920-134-1 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
21/01/2021
21/01/2021
21/01/2021
08/03/2021
08/03/2021
08/03/2021
cobalt carbonate 208-169-4 513-79-1
Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2)
Carcinogenicity || Note: testing proposed with Cobalt dichloride (EC 231-589-4)
21/01/2021
21/01/2021
08/03/2021
08/03/2021
Cobalt dihydroxide 244-166-4 21041-93-0
Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2)
Carcinogenicity || Note: testing proposed with Cobalt dichloride (EC 231-589-4)
21/01/2021
21/01/2021
08/03/2021
08/03/2021
cobalt dinitrate 233-402-1 10141-05-6
Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2)
Carcinogenicity || Note: testing proposed with Cobalt dichloride (EC 231-589-4)
21/01/2021
21/01/2021
08/03/2021
08/03/2021
Cobalt oxide 215-154-6 1307-96-6
Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2)
Carcinogenicity || Note: testing proposed with Cobalt dichloride (EC 231-589-4)
21/01/2021
21/01/2021
08/03/2021
08/03/2021
cobalt sulphate 233-334-2 10124-43-3
Genetic toxicity in vivo
Carcinogenicity || Note: testing proposed with Cobalt dichloride (EC 231-589-4)
21/01/2021
21/01/2021
08/03/2021
08/03/2021
OO-tert-butyl O-(2-ethylhexyl) peroxycarbonate 252-029-5 34443-12-4
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
21/01/2021
21/01/2021
08/03/2021
08/03/2021
Rectified Hydrocarbons by-products from synthetic process of Turpentine and acid, alcohols fraction 949-141-8 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
21/01/2021
21/01/2021
08/03/2021
08/03/2021
4,4'-Isopropylidenediphenol, ethoxylated, esters with fatty acids, coco 500-303-2 115340-85-7 Genetic toxicity in vivo 21/01/2021 08/03/2021
Androst-4-ene-3,17-dione 200-554-5 63-05-8 Long-term toxicity to fish 21/01/2021 08/03/2021
Cobalt, borate neodecanoate complexes 270-601-2 68457-13-6 Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2) 21/01/2021 08/03/2021
Distillates (petroleum), full-range straight-run middle 272-341-5 68814-87-9 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Distillates (petroleum), heavy straight-run (EC 272-817-2) (CAS 68915-96-8) 21/01/2021 08/03/2021
Fatty acids, C14-C18 and C18 unsaturated, amides with 2,2’-iminodiethanol 948-052-1 - Reproductive toxicity (extended one-generation reproductive toxicity study) 21/01/2021 08/03/2021
N-(2-hydroxyethyl)-N-[2-[(1-oxooctyl)amino]ethyl]-β-alanine 264-761-2 64265-45-8 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Amphoacetates C8-C18 (EC 931-291-0) || Note: Testing proposal is based on concern identified by the registrant 21/01/2021 08/03/2021
Neodecanoic acid, cobalt salt 248-373-0 27253-31-2 Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2) || Note: Testing proposal is based on concern identified by the registrant 21/01/2021 08/03/2021
Resin acids and Rosin acids, cobalt salts 273-321-9 68956-82-1 Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2) 21/01/2021 08/03/2021
Silicic acid (H4SiO4), tetraethyl ester, reaction products with bis(acetyloxy)dibutylstannane 300-344-4 93925-42-9 Genetic toxicity in vivo 21/01/2021 08/03/2021
Stearic acid, cobalt salt 237-016-4 13586-84-0 Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2) 21/01/2021 08/03/2021
Trisodium 4-amino-5-hydroxy-3-[[4-[[2-oxo-1-[(phenylamino)carbonyl]propyl]azo]phenyl]azo]-6-[(4-sulphonato-1-naphthyl)azo]naphthalene-2,7-disulphonate 279-093-7 79135-92-5 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 21/01/2021 08/03/2021
1-(2-hydroxyethyl)pyrrolidin-2-one 222-359-4 3445-11-2
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
16/12/2020
16/12/2020
16/12/2020
01/02/2021
01/02/2021
01/02/2021
2-butene 203-452-9 107-01-7
Sub-chronic toxicity (90 day): inhalation || Note: substance belongs to a category and testing is proposed with Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC 306-004-1)
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: substance belongs to a category and testing is proposed with 2-methylpropene (EC 204-066-3) and Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC 306-004-1)
Reproductive toxicity (pre-natal developmental toxicity) || Note: substance belongs to a category and testing is proposed with 2-methylpropene (EC 204-066-3) and Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC 306-004-1)
16/12/2020
16/12/2020
16/12/2020
01/02/2021
01/02/2021
01/02/2021
2-methylpropene 204-066-3 115-11-7
Sub-chronic toxicity (90 day): inhalation || Note: substance belongs to a category and testing is proposed with Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC 306-004-1)
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: substance belongs to a category and testing is proposed with the Substance (EC 204-066-3) and Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC 306-004-1)
Reproductive toxicity (pre-natal developmental toxicity) || Note: substance belongs to a category and testing is proposed with the Substance (EC 204-066-3) and Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC 306-004-1)
16/12/2020
16/12/2020
16/12/2020
01/02/2021
01/02/2021
01/02/2021
But-1-ene 203-449-2 106-98-9
Sub-chronic toxicity (90 day): inhalation || Note: substance belongs to a category and testing is proposed with Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC 306-004-1)
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: substance belongs to a category and testing is proposed with 2-methylpropene (EC 204-066-3) and Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC 306-004-1)
Reproductive toxicity (pre-natal developmental toxicity) || Note: substance belongs to a category and testing is proposed with 2-methylpropene (EC 204-066-3) and Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC 306-004-1)
16/12/2020
16/12/2020
16/12/2020
01/02/2021
01/02/2021
01/02/2021
Dibenzoyl peroxide 202-327-6 94-36-0
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
16/12/2020
16/12/2020
16/12/2020
01/02/2021
01/02/2021
01/02/2021
3,9-dimethyl-2,4,8,10-tetraoxa-3,9-diphosphaspiro[5.5]undecane 3,9-dioxide 221-088-9 3001-98-7
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
16/12/2020
16/12/2020
01/02/2021
01/02/2021
5,5'-dithiodi-1,3,4-thiadiazole-2(3H)-thione 276-763-0 72676-55-2
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
16/12/2020
16/12/2020
01/02/2021
01/02/2021
Carboxymethyldimethyl-3-[[(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)sulphonyl]amino]propylammonium hydroxide 252-046-8 34455-29-3
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
16/12/2020
16/12/2020
01/02/2021
01/02/2021
Hexan-6-olide 207-938-1 502-44-3
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
16/12/2020
16/12/2020
01/02/2021
01/02/2021
Nonane-1,9-diol 223-517-5 3937-56-2
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
16/12/2020
16/12/2020
01/02/2021
01/02/2021
Reaction mass of dibutyl adipate and dibutyl glutarate 936-196-8 -
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Reaction mass of dimethyl adipate, dimethyl glutarate and dimethyl succinate (EC 906-170-0)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Reaction mass of dimethyl adipate, dimethyl glutarate and dimethyl succinate (EC 906-170-0)
16/12/2020
16/12/2020
01/02/2021
01/02/2021
2,2'-(octadecylimino)bisethanol 233-520-3 10213-78-2 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 2,2'-(octadec-9-enylimino)bisethanol EC 246-807-3 16/12/2020 01/02/2021
2,5-bis(1,1,3,3-tetramethylbutyl)hydroquinone 212-990-3 903-19-5 Genetic toxicity in vivo 16/12/2020 01/02/2021
2-Naphthalenol, 1-[[4-(phenylazo)phenyl]azo]-, ar-heptyl ar',ar''-Me derivs. 296-120-8 92257-31-3 Genetic toxicity in vivo 16/12/2020 01/02/2021
4'-Ethyl-2,3-difluorbiphenyl-4-boronic acid 929-209-3 - Genetic toxicity in vivo 16/12/2020 01/02/2021
4,4'-isopropylidenedicyclohexanol 201-244-2 80-04-6 Genetic toxicity in vivo 16/12/2020 01/02/2021
Alcohols, C13-15-branched and linear 287-625-4 85566-16-1 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Isotridecan-1-ol (EC 248-469-2) 16/12/2020 01/02/2021
Barium hydroxide 241-234-5 17194-00-2 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Barium chloride dihydrate (EC 600-412-6) 16/12/2020 01/02/2021
bis(α,α-dimethylbenzyl) peroxide 201-279-3 80-43-3 Reproductive toxicity (extended one-generation reproductive toxicity study) 16/12/2020 01/02/2021
Isotridecan-1-ol 248-469-2 27458-92-0 Reproductive toxicity (extended one-generation reproductive toxicity study) 16/12/2020 01/02/2021
Methyl trimethyl-3-[(1-oxododecyl)amino]propylammonium sulphate 234-204-8 10595-49-0 Reproductive toxicity (pre-natal developmental toxicity) 16/12/2020 01/02/2021
methyl-1h-benzotriazole 249-596-6 29385-43-1 Sub-chronic toxicity (90-day): oral 16/12/2020 01/02/2021
Octasodium 2,2'-[1,4-phenylenebis[imino(6-chloro-1,3,5-triazine-4,2-diyl)imino(1-hydroxy-3,6-disulphonatonaphthalene-2,8-diyl)azo]]bisnaphthalene-1,5-disulphonate 275-108-6 71002-20-5 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant 16/12/2020 01/02/2021
Propylenediamine 201-155-9 78-90-0 Reproductive toxicity (pre-natal developmental toxicity) 16/12/2020 01/02/2021
Propylidynetrimethanol, ethoxylated, esters with acrylic acid, reaction products with diethylamine 500-425-6 159034-91-0 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant 16/12/2020 01/02/2021
Reaction mass of (E)-3-methyl-5-phenylpent-2-enenitrile and (Z)-3-methyl-5-phenylpent-2-enenitrile 299-682-2 93893-89-1 Reproductive toxicity (pre-natal developmental toxicity) 16/12/2020 01/02/2021
Reaction mass of 6-Chloro-2-{4[ethyl(2-hydroxyethyl)amino]phenyl}-1-methylbenzo[cd]indolium hydroxide and 6-chloro-2-[4-[ethyl(2-hydroxyethyl)amino]phenyl]-1-methylbenz[cd]indolium acetate 946-378-9 - Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant 16/12/2020 01/02/2021
Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C11-17 and C17 unsatd. alkyl) derivs. and sodium hydroxide and 2-propenoic acid 946-533-0 - Sub-chronic toxicity (90-day): oral || Note: testing proposed with β-Alanine, N-(2-aminoethyl)-N-(2-hydroxyethyl)-, N-coco acyl derivs., monosodium salts (EC 298-632-7) 16/12/2020 01/02/2021
Reaction products of tetrazotized 5-amino-2-[(E)-2-(4-amino-2-sulfophenyl)ethenyl]benzenesulfonic acid with 6-amino-4-hydroxynaphthalene-2-sulfonic acid and 4-amino-5-hydroxynaphthalene-2,7-disulfonic acid in 2-[bis(2-hydroxyethyl)amino]ethanol 916-899-6 - Genetic toxicity in vivo 16/12/2020 01/02/2021
Sodium 4(or 5)-methyl-1H-benzotriazolide 265-004-9 64665-57-2 Sub-chronic toxicity (90-day): oral || Note: testing proposed with Tolyltriazole (EC 249-596-6) 16/12/2020 01/02/2021
Terephthalic acid 202-830-0 100-21-0 Reproductive toxicity (pre-natal developmental toxicity) 16/12/2020 01/02/2021
Trimethyl-3-[(1-oxo-10-undecenyl)amino]propylammonium methyl sulphate 304-990-8 94313-91-4 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Methyl trimethyl-3-[(1-oxododecyl)amino]propylammonium sulphate EC 234-204-8 || Note: Testing proposal is based on concern identified by the registrant 16/12/2020 01/02/2021
Alkanes, C12-14-iso- 271-369-5 68551-19-9
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Hydrocarbons, C7-C9, isoalkanes (EC 921-728-3) || Note: testing proposed with Isohexadecane 2,2,4,4,6,8,8-heptamethylnonane (EC 224-506-8)
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Hydrocarbons, C7-C9, isoalkanes (EC 921-728-3) || Note: testing proposed with Isohexadecane 2,2,4,4,6,8,8-heptamethylnonane (EC 224-506-8)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Hydrocarbons, C7-C9, isoalkanes (EC 921-728-3) || Note: testing proposed with Isohexadecane 2,2,4,4,6,8,8-heptamethylnonane (EC 224-506-8)
23/11/2020
23/11/2020
23/11/2020
07/01/2021
07/01/2021
07/01/2021
3-trimethoxysilylpropane-1-thiol 224-588-5 4420-74-0
Sub-chronic toxicity (90-day): oral || Note: testing proposed with 3-(triethoxysilyl)propanethiol (EC 238-883-1) || Note: Testing proposal is based on concern identified by the registrant.
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 3-(triethoxysilyl)propanethiol (EC 238-883-1) || Note: Testing proposal is based on concern identified by the registrant.
23/11/2020
23/11/2020
07/01/2021
07/01/2021
4,6-dichloro-N-(1,1,3,3-tetramethylbutyl)-1,3,5-triazin-2-amine 276-309-1 72058-41-4
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
23/11/2020
23/11/2020
07/01/2021
07/01/2021
Ethyl 4-oxovalerate 208-728-2 539-88-8
Sub-chronic toxicity (90-day): oral || Note: testing proposed with levulinic acid (EC 204-649-2)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with levulinic acid (EC 204-649-2)
23/11/2020
23/11/2020
07/01/2021
07/01/2021
Fatty acids, C18 (linear and branched, unsaturated) and fatty acids C18 (linear and branched, unsaturated) -N,N-dibutylamide, monosulphated, sodium salts 915-926-9 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
23/11/2020
23/11/2020
07/01/2021
07/01/2021
Hexene 246-768-2 25264-93-1
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Hex-1-ene (EC 209-753-1) || Note: testing proposed with Octadec-1-ene (EC 112-88-9) || Note: testing proposed with Hexadecene (EC 248-131-4) || Note: testing proposed with Alkenes, C8-10, C9-rich (EC 271-212-0) || Note: testing proposed with Nonene, branched (EC 306-492-6)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Hex-1-ene (EC 209-753-1) || Note: testing proposed with Octadec-1-ene (EC 112-88-9) || Note: testing proposed with Octadecene (EC 248-205-6) || Note: testing proposed with Alkenes, C8-10, C9-rich (EC 271-212-0) || Note: testing proposed with Nonene, branched (EC 306-492-6)
23/11/2020
23/11/2020
07/01/2021
07/01/2021
N-butyl 4-oxopentanoate 218-143-4 2052-15-5
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Levulinic acid (EC 204-649-2)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Levulinic acid (EC 204-649-2)
23/11/2020
23/11/2020
07/01/2021
07/01/2021
(octahydro-4,7-methano-1H-indenyl)methyl acrylate 300-723-4 93962-84-6 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 23/11/2020 07/01/2021
1,3-Propanediol, 2,2-bis(hydroxymethyl)-, allyl ether 293-883-9 91648-24-7 Bioaccumulation aquatic / sediment || Note: Testing proposal is based on concern identified by the registrant. 23/11/2020 07/01/2021
2-[(1-amino-9,10-dihydro-4-hydroxy-9,10-dioxo-2-anthryl)oxy]ethyl ethyl carbonate 254-959-7 40530-60-7 Genetic toxicity in vivo || Note: testing proposed with Disperse Red 302:1 (EC 248-882-8) 23/11/2020 07/01/2021
2-[(1-amino-9,10-dihydro-4-hydroxy-9,10-dioxo-2-anthryl)oxy]ethyl phenyl carbonate 248-882-8 28173-59-3 Genetic toxicity in vivo 23/11/2020 07/01/2021
4,4'-[2,2,2-trifluoro-1-(trifluoromethyl)ethylidene]diphenol; bisphenol AF 216-036-7 1478-61-1 Genetic toxicity in vivo 23/11/2020 07/01/2021
Amines, C11-14-branched alkyl, monohexyl and dihexyl phosphates 279-632-6 80939-62-4 Sub-chronic toxicity (90-day): oral 23/11/2020 07/01/2021
Amines, C12-14-tert-alkyl, mixed sec-Bu and iso-Bu phosphates 306-227-4 96690-34-5 Sub-chronic toxicity (90-day): oral || Note: testing proposed with Amines, C11-14-branched alkyl, monohexyl and dihexyl phosphates (EC 279-632-6) || Note: Testing proposal is based on concern identified by the registrant. 23/11/2020 07/01/2021
Cesium fluoroaluminate 604-086-6 138577-01-2 Genetic toxicity in vivo 23/11/2020 07/01/2021
Distillates (petroleum), straight-run middle 265-044-7 64741-44-2 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Distillates (petroleum), heavy straight-run (EC 272-817-2) 23/11/2020 07/01/2021
Fluoren-9-one 207-630-7 486-25-9 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 23/11/2020 07/01/2021
Hydrogen [4-[[4-(diethylamino)phenyl][4-[ethyl[(3-sulphonatobenzyl)amino]-o-tolyl]methylene]-3-methylcyclohexa-2,5-dien-1-ylidene](ethyl)(3-sulphonatobenzyl)ammonium, sodium salt 229-390-2 6505-30-2 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 23/11/2020 07/01/2021
Hydroxyacetone 204-124-8 116-09-6 Genetic toxicity in vivo 23/11/2020 07/01/2021
Manganese dioxide 215-202-6 1313-13-9 Genetic toxicity in vivo 23/11/2020 07/01/2021
N-[2-[(2-cyano-4,6-dinitrophenyl)azo]-5-(diethylamino)phenyl]acetamide 246-058-2 24170-60-3 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 23/11/2020 07/01/2021
Octene, hydroformylation products, low-boiling 273-110-1 68938-03-4 Reproductive toxicity (pre-natal developmental toxicity) 23/11/2020 07/01/2021
OO-tert-butyl monoperoxymaleate 217-691-1 1931-62-0 Genetic toxicity in vivo 23/11/2020 07/01/2021
Quinazolin-4(1H)-one 207-735-8 491-36-1 Genetic toxicity in vivo 23/11/2020 07/01/2021
Reaction mass of Ethanaminium, 2-hydroxy-N,N-dimethyl-N-[2-[(1-oxooctadecyl)oxy]ethyl]-, chloride and Ethanaminium, N,N-dimethyl-2-[(1-oxohexadecyl)oxy]-N-[2-[(1-oxooctadecyl)oxy]ethyl]-, chloride 951-974-7 - Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Ethanaminium, 2-hydroxy-N-(2-hydroxyethyl)-N,N-dimethyl-, esters with C16-18 and C18-unsatd. fatty acids, chlorides (EC 620-174-7) 23/11/2020 07/01/2021
Reaction products of tetrazotized 5-amino-2-[(E)-2-(4-amino-2-sulfophenyl)ethenyl]benzenesulfonic acid with 6-amino-4-hydroxynaphthalene-2-sulfonic acid and 4-amino-5-hydroxynaphthalene-2,7-disulfonic acid in 2-[bis(2-hydroxyethyl)amino]ethanol 916-899-6 - Genetic toxicity in vivo 23/11/2020 07/01/2021
Strontium bis(2-ethylhexanoate) 219-536-3 2457-02-5 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with [strontium oxide] (EC 215-219-9) 23/11/2020 07/01/2021
Ytterbium (III) oxide 215-234-0 1314-37-0 Genetic toxicity in vivo 23/11/2020 07/01/2021
Fatty acids, C12-18 (even numbered)-methyl esters, sulfonated, sodium salts 947-394-9 -
Long-term toxicity to fish
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
19/10/2020
19/10/2020
19/10/2020
03/12/2020
03/12/2020
03/12/2020
(E)-1,1,1,2,3,4,5,5,5-Nonafluoro-4-(trifluoromethyl)pent-2-ene 807-113-1 3709-71-5
Sub-chronic toxicity (90 day): inhalation
Reproductive toxicity (pre-natal developmental toxicity)
19/10/2020
19/10/2020
03/12/2020
03/12/2020
1,2-dimethylimidazole 217-101-2 1739-84-0
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
19/10/2020
19/10/2020
03/12/2020
03/12/2020
1,5-Pentanediamine, 2-methyl-, reaction products with 2-ethyl-1,4-butanediamine and glycidyl tolyl ether 291-813-1 90480-76-5
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
19/10/2020
19/10/2020
03/12/2020
03/12/2020
Acetic acid, chloro-, sodium salt, reaction products with 4,5-dihydro-2-undecyl-1H-imidazole-1-ethanol and sodium hydroxide 271-794-6 68608-66-2
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Alkylamidoamine glycinate majority C12, 14 (amphoacetate) EC 931-291-0 || Note: Testing proposal is based on concern identified by the registrant
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Alkylamidoamine glycinate majority C12, 14 (amphoacetate) EC 931-291-0. || Note: Testing proposal is based on concern identified by the registrant
19/10/2020
19/10/2020
03/12/2020
03/12/2020
(2,4,6-trioxo-1,3,5-triazine-1,3,5(2H,4H,6H)-triyl)tri-2,1-ethanediyl triacrylate 254-843-6 40220-08-4 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant 19/10/2020 03/12/2020
14H-benz[4,5]isoquino[2,1-a]perimidin-14-one 229-904-5 6829-22-7 Genetic toxicity in vivo 19/10/2020 03/12/2020
2,3-epoxypropyl isopropyl ether 223-672-9 4016-14-2 Genetic toxicity in vivo 19/10/2020 03/12/2020
3-(benzothiazol-2-yl)-7-(diethylamino)-2-oxo-2H-1-benzopyran-4-carbonitrile 274-668-9 70546-25-7 Genetic toxicity in vivo 19/10/2020 03/12/2020
4-[3-(1-naphthylamino)propyl]morpholine 226-033-2 5235-82-5 Genetic toxicity in vivo 19/10/2020 03/12/2020
5-bromo-5-nitro-1,3-dioxane 250-001-7 30007-47-7 Genetic toxicity in vivo 19/10/2020 03/12/2020
7,7,9(or 7,9,9)-trimethyl-4,13-dioxo-3,14-dioxa-5,12-diazahexadecane-1,16-diyl bismethacrylate 276-957-5 72869-86-4 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant 19/10/2020 03/12/2020
[1R-(1α,2β,5α)]-1-(isopropyl)-2-methoxy-4-methylcyclohexane 216-365-6 1565-76-0 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant 19/10/2020 03/12/2020
Cyclohexanone, peroxide 235-527-7 12262-58-7 Genetic toxicity in vivo 19/10/2020 03/12/2020
Dirhodium trisulphate 234-014-5 10489-46-0 Genetic toxicity in vivo 19/10/2020 03/12/2020
Disodium 5-[[4-[(2-bromo-1-oxoallyl)amino]-2-sulphonatophenyl]azo]-4-hydroxy-6-(methylamino)naphthalene-2-sulphonate 274-436-7 70210-39-8 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant 19/10/2020 03/12/2020
Essential oil of Spearmint obtained from the aerial part of Mentha spicata and/or Mentha cardiaca (Lamiaceae) obtained by distillation 946-253-9 - Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant 19/10/2020 03/12/2020
Phosphoric acid, C11-14 (C13-rich)-isoalkyl mono- and di-esters, partially salted with 1-Propanamine, 3-(tridecyloxy)-, branched 947-480-6 - Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposal is based on concern identified by the registrant 19/10/2020 03/12/2020
Reaction mass of Disodium dihydroxy[3-(hydroxy-kO)-4-{[5-(hydroxy-kO)-3-methyl-1-phenyl-1Hpyrazol-4-yl]diazenyl-kN1}naphthalene-1-sulfonato(3-)]chromate(2-) and sodium [4-[(4,5-dihydro-3-methyl-5-oxo-1-phenyl-1H-pyrazol-4-yl)azo]-3-hydroxynaphthalene-1-sulphonato(3-)]hydroxychromate(1-) 944-272-7 - Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant 19/10/2020 03/12/2020
Reaction mass of N-butylphthalimide and N-sec-butylphthalimide and N-propylphthalimide 943-947-3 - Genetic toxicity in vivo 19/10/2020 03/12/2020
Cobalt hydroxide oxide 234-614-7 12016-80-7
Sub-chronic toxicity (90 day): inhalation || Note: testing proposed with Tricobalt tetraoxide (EC 215-157-2) || Note: Testing proposal is based on concern identified by the registrant
Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2) || Note: Testing proposal is based on concern identified by the registrant.
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Cobalt sulphide (EC 215-273-3) || Note: Testing proposal is based on concern identified by the registrant.
21/09/2020
21/09/2020
21/09/2020
05/11/2020
05/11/2020
05/11/2020
Cobalt sulphide 215-273-3 1317-42-6
Sub-chronic toxicity (90 day): inhalation || Note: testing proposed with Tricobalt tetraoxide (EC 215-157-2) || Note: Testing proposal is based on concern identified by the registrant
Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2) || Note: Testing proposal is based on concern identified by the registrant.
Reproductive toxicity (extended one-generation reproductive toxicity study)
21/09/2020
21/09/2020
21/09/2020
05/11/2020
05/11/2020
05/11/2020
Tricobalt tetraoxide 215-157-2 1308-06-1
Sub-chronic toxicity (90 day): inhalation
Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2) || Note: Testing proposal is based on concern identified by the registrant.
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Cobalt sulphide (EC 215-273-3) || Note: Testing proposal is based on concern identified by the registrant.
21/09/2020
21/09/2020
21/09/2020
05/11/2020
05/11/2020
05/11/2020
Cobalt 231-158-0 7440-48-4
Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2) || Note: Testing proposal is based on concern identified by the registrant.
Carcinogenicity || Note: testing proposed with Cobalt dichloride (EC 231-589-4) || Note: Testing proposal is based on concern identified by the registrant.
21/09/2020
21/09/2020
05/11/2020
05/11/2020
Cobalt bis(2-ethylhexanoate) 205-250-6 136-52-7
Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2) || Note: Testing proposal is based on concern identified by the registrant.
Carcinogenicity || Note: testing proposed with Cobalt dichloride (EC 231-589-4) || Note: Testing proposal is based on concern identified by the registrant.
21/09/2020
21/09/2020
05/11/2020
05/11/2020
cobalt di(acetate) 200-755-8 71-48-7
Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2) || Note: Testing proposal is based on concern identified by the registrant.
Carcinogenicity || Note: testing proposed with Cobalt dichloride (EC 231-589-4) || Note: Testing proposal is based on concern identified by the registrant
21/09/2020
21/09/2020
05/11/2020
05/11/2020
Cobalt dichloride 231-589-4 7646-79-9
Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2) || Note: Testing proposal is based on concern identified by the registrant.
Carcinogenicity || Note: Testing proposal is based on concern identified by the registrant.
21/09/2020
21/09/2020
05/11/2020
05/11/2020
Cobalt lithium dioxide 235-362-0 12190-79-3
Sub-chronic toxicity (90 day): inhalation || Note: testing proposed with Tricobalt tetraoxide (EC 215-157-2) || Note: Testing proposal is based on concern identified by the registrant.
Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2) || Note: Testing proposal is based on concern identified by the registrant.
21/09/2020
21/09/2020
05/11/2020
05/11/2020
Cobalt oxalate 212-409-3 814-89-1
Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2) || Note: Testing proposal is based on concern identified by the registrant.
Carcinogenicity || Note: testing proposed with Cobalt dichloride (EC 231-589-4) || Note: Testing proposal is based on concern identified by the registrant.
21/09/2020
21/09/2020
05/11/2020
05/11/2020
Cobalt(II) 4-oxopent-2-en-2-olate 237-855-6 14024-48-7
Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2) || Note: Testing proposal is based on concern identified by the registrant.
"Carcinogenicity || Note: testing proposed with Cobalt dichloride (EC 231-589-4) || Note: Testing proposal is based on concern identified by the registrant. "
21/09/2020
21/09/2020
05/11/2020
05/11/2020
Cobalt, borate propionate complexes 295-033-2 91782-61-5
Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2) || Note: Testing proposal is based on concern identified by the registrant.
Carcinogenicity || Note: testing proposed with Cobalt dichloride (EC 231-589-4) || Note: Testing proposal is based on concern identified by the registrant.
21/09/2020
21/09/2020
05/11/2020
05/11/2020
4-(1-oxo-2-propenyl)-morpholine 418-140-1 5117-12-4 Genetic toxicity in vivo 21/09/2020 05/11/2020
Benzenamine, reaction products with aniline hydrochloride and nitrobenzene, hydrochlorides 309-913-1 101357-16-8 Sub-chronic toxicity (90-day): oral 21/09/2020 05/11/2020
Di(tetraethylammonium)hexahydroxoplatinate(IV) 848-537-7 1912392-88-1 Genetic toxicity in vivo 21/09/2020 05/11/2020
Diethylamine 203-716-3 109-89-7 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Dimethylamine (CAS 124-40-3) 21/09/2020 05/11/2020
Fuels, diesel, co-processed with hydrocarbons derived from thermally cracked waste plastics 951-495-3 -
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Gas oils (petroleum), light vacuum (EC 265-059-9)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with
- Gas oils (petroleum), light vacuum (EC 265-059-9)
- Fuel oil, no. 4 (EC 270-673-5)
- Distillates (petroleum), light hydrocracked (EC 265-078-2)
- Fuels, diesel (EC 269-822-7)
24/08/2020
24/08/2020
08/10/2020
08/10/2020
4-(4-isopropoxyphenylsulfonyl)phenol 405-520-5 95235-30-6 Reproductive toxicity (pre-natal developmental toxicity) 24/08/2020 08/10/2020
Alkanoic acid and polyoxomolybdate borate alkanoate clusters 944-813-7 - Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant 24/08/2020 08/10/2020
Bisisopropyl peroxydicarbonate 203-317-4 105-64-6 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant 24/08/2020 08/10/2020
Reaction mass of bisisopropyl peroxydicarbonate and bis-sec-butyl peroxydicarbonate and isopropyl-sec-butylperoxydicarbonate 931-536-1 - Genetic toxicity in vivo || Note: testing proposed with bisisopropyl peroxydicarbonate EC 203-317-4, CAS 105-64-6 (is a constituent of the multi-constituent registered substance) || Note: Testing proposal is based on concern identified by the registrant 24/08/2020 08/10/2020
Gas oils (petroleum), light vacuum 265-059-9 64741-58-8
Sub-chronic toxicity (90-day): oral
Sub-chronic toxicity (90 day): dermal
Genetic toxicity in vivo
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
07/07/2020
07/07/2020
07/07/2020
07/07/2020
07/07/2020
21/08/2020
21/08/2020
21/08/2020
21/08/2020
21/08/2020
Condensates (petroleum), vacuum tower 265-049-4 64741-49-7
Sub-chronic toxicity (90 day): dermal || Note: testing proposed with - Gas oils (petroleum), light vacuum (EC 265-059-9) - Fuel oil, no. 4 (EC 270-673-5) - Distillates (petroleum), light hydrocracked (EC 265-078-2)
Genetic toxicity in vivo || Note: testing proposed with - Gas oils (petroleum), light vacuum (EC 265-059-9) - Fuels, diesel (EC 269-822-7) - Fuel oil, no. 4 (EC 270-673-5) - Distillates (petroleum), light hydrocracked (EC 265-078-2)
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Gas oils (petroleum), light vacuum (EC 265-059-9)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with - Gas oils (petroleum), light vacuum (EC 265-059-9) - Fuel oil, no. 4 (EC 270-673-5) - Distillates (petroleum), light hydrocracked (EC 265-078-2) - Fuels, diesel (EC 269-822-7)
07/07/2020
07/07/2020
07/07/2020
07/07/2020
21/08/2020
21/08/2020
21/08/2020
21/08/2020
Distillates (petroleum), light hydrocracked 265-078-2 64741-77-1
Sub-chronic toxicity (90 day): dermal
Genetic toxicity in vivo
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Gas oils (petroleum), light vacuum (EC 265-059-9)
Reproductive toxicity (pre-natal developmental toxicity)
07/07/2020
07/07/2020
07/07/2020
07/07/2020
21/08/2020
21/08/2020
21/08/2020
21/08/2020
Fuel oil, no. 2 270-671-4 68476-30-2
Sub-chronic toxicity (90 day): dermal || Note: testing proposed with - Gas oils (petroleum), light vacuum (EC 265-059-9) - Fuel oil, no. 4 (EC 270-673-5) - Distillates (petroleum), light hydrocracked (EC 265-078-2)
Genetic toxicity in vivo || Note: testing proposed with - Gas oils (petroleum), light vacuum (EC 265-059-9) - Fuels, diesel (EC 269-822-7) - Fuel oil, no. 4 (EC 270-673-5) - Distillates (petroleum), light hydrocracked (EC 265-078-2)
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Gas oils (petroleum), light vacuum (EC 265-059-9)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with - Gas oils (petroleum), light vacuum (EC 265-059-9) - Fuel oil, no. 4 (EC 270-673-5) - Distillates (petroleum), light hydrocracked (EC 265-078-2) - Fuels, diesel (EC 269-822-7)
07/07/2020
07/07/2020
07/07/2020
07/07/2020
21/08/2020
21/08/2020
21/08/2020
21/08/2020
Fuel oil, no. 4 270-673-5 68476-31-3
Sub-chronic toxicity (90 day): dermal
Genetic toxicity in vivo
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Gas oils (petroleum), light vacuum, (EC 265-059-9)
Reproductive toxicity (pre-natal developmental toxicity)
07/07/2020
07/07/2020
07/07/2020
07/07/2020
21/08/2020
21/08/2020
21/08/2020
21/08/2020
Fuels, diesel, no. 2 270-676-1 68476-34-6
Sub-chronic toxicity (90 day): dermal || Note: testing proposed with - Gas oils (petroleum), light vacuum (EC 265-059-9) - Fuel oil, no. 4 (EC 270-673-5) - Distillates (petroleum), light hydrocracked (EC 265-078-2)
Genetic toxicity in vivo || Note: testing proposed with - Gas oils (petroleum), light vacuum (EC 265-059-9) - Fuels, diesel (EC 269-822-7) - Fuel oil, no. 4 (EC 270-673-5) - Distillates (petroleum), light hydrocracked (EC 265-078-2)
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Gas oils (petroleum), light vacuum (EC 265-059-9)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with - Gas oils (petroleum), light vacuum (EC 265-059-9) - Fuel oil, no. 4 (EC 270-673-5) - Distillates (petroleum), light hydrocracked (EC 265-078-2) - Fuels, diesel (EC 269-822-7)
07/07/2020
07/07/2020
07/07/2020
07/07/2020
21/08/2020
21/08/2020
21/08/2020
21/08/2020
Gas oils (petroleum), hydrodesulfurized light vacuum 265-190-1 64742-87-6
Sub-chronic toxicity (90 day): dermal || Note: testing proposed with category members - Gas oils (petroleum), light vacuum (EC 265-059-9) - Fuel oil, no. 4 (EC 270-673-5) - Distillates (petroleum), light hydrocracked (EC 265-078-2)
Genetic toxicity in vivo || Note: testing proposed with category members Gas oils (petroleum), light vacuum (EC 265-059-9), Fuels, diesel (EC 269-822-7), Fuel oil, no. 4 (EC 270-673-5), Distillates (petroleum), light hydrocracked (EC 265-078-2)
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Gas oils (petroleum), light vacuum (EC 265-059-9)
Reproductive toxicity (pre-natal developmental toxicity) 1st (Rat) and 2nd species (Rabbit) (Dermal route) || Note: testing proposed with category members Gas oils (petroleum), light vacuum (EC 265-059-9), Fuels, diesel (EC 269-822-7), Fuel oil, no. 4 (EC 270-673-5), Distillates (petroleum), light hydrocracked (EC 265-078-2)
07/07/2020
07/07/2020
07/07/2020
07/07/2020
21/08/2020
21/08/2020
21/08/2020
21/08/2020
Fuels, diesel 269-822-7 68334-30-5
Genetic toxicity in vivo
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Gas oils (petroleum), light vacuum (EC 265-059-9)
Reproductive toxicity (pre-natal developmental toxicity)
07/07/2020
07/07/2020
07/07/2020
21/08/2020
21/08/2020
21/08/2020
Cobalt, borate 2-ethylhexanoate complexes 295-032-7 91782-60-4
Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2) || Note: Testing proposal is based on concern identified by the registrant
Carcinogenicity || Note: testing proposed with Cobalt dichloride (EC 231-589-4) || Note: Testing proposal is based on concern identified by the registrant
07/07/2020
07/07/2020
21/08/2020
21/08/2020
Triethoxyhexadecylsilane 240-465-9 16415-13-7
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Hexadecyltrimethoxysilane (EC 240-464-3) || Note: Testing proposal is based on concern identified by the registrant
07/07/2020
07/07/2020
21/08/2020
21/08/2020
[3-(trimethoxysilyl)propyl]urea 245-904-8 23843-64-3 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Urea, N-(3-silylpropyl)-, Si-(ethoxy and methoxy) derivs., (EC 601-461-6) || Note: Testing proposal is based on concern identified by the registrant 07/07/2020 21/08/2020
Bis(triethoxysilylpropyl)amine 236-818-1 13497-18-2 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Bis(trimethoxysilylpropyl)amine (EC 403-480-3) || Note: Testing proposal is based on concern identified by the registrant 07/07/2020 21/08/2020
Polyamide wax 434-430-9 - Long-term toxicity to fish 07/07/2020 21/08/2020
4,4,7,7-tetraethoxy-3,8-dioxa-4,7-disiladecane 240-212-2 16068-37-4
Long-term toxicity to fish
Sub-chronic toxicity (90-day): oral
Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant
Reproductive toxicity (pre-natal developmental toxicity)
17/06/2020
17/06/2020
17/06/2020
17/06/2020
03/08/2020
03/08/2020
03/08/2020
03/08/2020
1,1,1,3,5,5,5-heptamethyl-3-octyltrisiloxane 241-881-3 17955-88-3
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
17/06/2020
17/06/2020
03/08/2020
03/08/2020
4,4'-(9H-fluoren-9-ylidene)bis(2-chloroaniline) 407-560-9 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
17/06/2020
17/06/2020
03/08/2020
03/08/2020
Bis(trimethoxysilylpropyl)amine 280-084-5 82985-35-1
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity
17/06/2020
17/06/2020
03/08/2020
03/08/2020
dodecamethylpentasiloxane 205-492-2 141-63-9
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
17/06/2020
17/06/2020
03/08/2020
03/08/2020
2,2'-azobis[4-methoxy-2,4-dimethylvaleronitrile] 239-593-8 15545-97-8 Genetic toxicity in vivo 17/06/2020 03/08/2020
2,6-di-tert-butylphenol 204-884-0 128-39-2 Reproductive toxicity (pre-natal developmental toxicity) 17/06/2020 03/08/2020
3,4-dihydroxybenzonitrile 241-367-9 17345-61-8 Genetic toxicity in vivo 17/06/2020 03/08/2020
[3-(2,3-epoxypropoxy)propyl]trimethoxysilane 219-784-2 2530-83-8 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant 17/06/2020 03/08/2020
Barium sulfate 231-784-4 7727-43-7 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Barium chloride (EC 233-788-1) 17/06/2020 03/08/2020
Citronellyl formate 203-338-9 105-85-1 Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposal is based on concern identified by the registrant 17/06/2020 03/08/2020
Dimethyl 2,2'-azobis(2-methylpropionate) 219-976-6 2589-57-3 Genetic toxicity in vivo 17/06/2020 03/08/2020
Linalyl acetate 204-116-4 115-95-7 Reproductive toxicity (extended one-generation reproductive toxicity study) 17/06/2020 03/08/2020
Maleic acid 203-742-5 110-16-7 Reproductive toxicity (pre-natal developmental toxicity) 17/06/2020 03/08/2020
N-(2-(4-amino-N-ethyl-m-toluidino)ethyl)methanesulphonamide sesquisulphate 247-161-5 25646-71-3 Genetic toxicity in vivo 17/06/2020 03/08/2020
N-acetylhexanelactam 217-565-6 1888-91-1 Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposal is based on concern identified by the registrant 17/06/2020 03/08/2020
Potassium 3-sulphonatopropyl acrylate 250-465-0 31098-20-1 Genetic toxicity in vivo 17/06/2020 03/08/2020
Potassium dicyanoargentate 208-047-0 506-61-6 Genetic toxicity in vivo 17/06/2020 03/08/2020
Potassium dicyanoaurate 237-748-4 13967-50-5 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant 17/06/2020 03/08/2020
Reaction mass of 2,4,6,8,10-pentamethyl-2,4,6,8,10-pentavinylcyclopentasiloxane and 2,4,6,8-tetramethyl-2,4,6,8-tetravinylcyclotetrasiloxane 911-381-6 - Long-term toxicity to fish || Note: testing proposed with 2,4,6,8-tetramethyl-2,4,6,8-tetravinylcyclotetrasiloxane (EC 219-863-1) || Note: Testing proposal is based on concern identified by the registrant 17/06/2020 03/08/2020
Reaction mass of disodium (sulphonatothio)acetate and sodium chloride 947-115-0 - Genetic toxicity in vivo 17/06/2020 03/08/2020
1-ethoxy-2-(2-methoxyethoxy)ethane 213-690-5 1002-67-1
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant.
Reproductive toxicity (pre-natal developmental toxicity)
25/05/2020
25/05/2020
25/05/2020
09/07/2020
09/07/2020
09/07/2020
1,4-dimethylpiperazine 203-412-0 106-58-1
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
25/05/2020
25/05/2020
09/07/2020
09/07/2020
2,2-dimethyl-1,3-dioxolan-4-ylmethanol 202-888-7 100-79-8
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
25/05/2020
25/05/2020
09/07/2020
09/07/2020
2,3-epoxypropyl neodecanoate 247-979-2 26761-45-5
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
25/05/2020
25/05/2020
09/07/2020
09/07/2020
2-ethyl-2-[[(1-oxoallyl)oxy]methyl]-1,3-propanediyl diacrylate; 2,2-bis(acryloyloxymethyl)butyl acrylate; trimethylolpropane triacrylate 239-701-3 15625-89-5
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
25/05/2020
25/05/2020
09/07/2020
09/07/2020
Ashes (residues), nonhazardous municipal solid waste 937-417-0 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
25/05/2020
25/05/2020
09/07/2020
09/07/2020
Dipotassium bis[μ-[tartrato(4-)-O1,O2:O3,O4]]diantimonate(2-) , stereoisomer 234-293-3 11071-15-1
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant.
Reproductive toxicity (pre-natal developmental toxicity)
25/05/2020
25/05/2020
09/07/2020
09/07/2020
N'-(1,3-dimethylbutylidene)-3-hydroxy-2-naphthohydrazide 435-860-1 214417-91-1
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
25/05/2020
25/05/2020
09/07/2020
09/07/2020
(3-chloropropyl)dimethoxymethylsilane 242-056-0 18171-19-2 Sub-chronic toxicity (90-day): oral 25/05/2020 09/07/2020
(R)-p-mentha-1,8-diene 227-813-5 5989-27-5 Reproductive toxicity (extended one-generation reproductive toxicity study) 25/05/2020 09/07/2020
1,2-Benzenedicarboxylic acid, benzyl C7-9-branched and linear alkyl esters 701-339-3 - Reproductive toxicity (pre-natal developmental toxicity) 25/05/2020 09/07/2020
1,3-Propanediamine, N-[3-((C11-14, C13-rich)oxy)propyl]- branched acetate 931-295-2 - Sub-chronic toxicity (90-day): oral 25/05/2020 09/07/2020
1-(4-(ACETYLOXY)-3-((ACETYLOXY)METHYL)PHENYL)ETHANONE 921-042-4 - Genetic toxicity in vivo 25/05/2020 09/07/2020
2,4,6,8,10-pentamethylcyclopentasiloxane 228-204-7 6166-86-5 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 2,4,6,8-tetramethylcyclotetrasiloxane (EC 219-137-4) 25/05/2020 09/07/2020
2,4,6,8-tetramethylcyclotetrasiloxane 219-137-4 2370-88-9 Reproductive toxicity (extended one-generation reproductive toxicity study) 25/05/2020 09/07/2020
4,4'-isopropylidenedi-o-cresol 201-240-0 79-97-0 Genetic toxicity in vivo 25/05/2020 09/07/2020
[1,3-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide 218-664-7 2212-81-9 Reproductive toxicity (extended one-generation reproductive toxicity study) “|| Note: testing proposed with [1,3(or 1,4)-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide CAS: 25155-25-3)” 25/05/2020 09/07/2020
Choline hydroxide 204-625-1 123-41-1 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Choline chloride (EC 200-655-4) 25/05/2020 09/07/2020
Dichlorobis(η-cyclopentadienyl)titanium 215-035-9 1271-19-8 Genetic toxicity in vivo 25/05/2020 09/07/2020
Dimethoxymethylsilane 240-914-9 16881-77-9 Sub-chronic toxicity (90-day): oral 25/05/2020 09/07/2020
hexadecyltrimethoxysilane 240-464-3 16415-12-6 Reproductive toxicity (extended one-generation reproductive toxicity study) 25/05/2020 09/07/2020
Lithium phosphorodifluoridate 643-080-8 24389-25-1 Reproductive toxicity (pre-natal developmental toxicity) 25/05/2020 09/07/2020



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