Previous Testing Proposals

Previous Testing Proposals

Previous Testing Proposals

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

There are currently no ongoing consultations.
 
Trimethylolpropane and its reaction products with methyloxirane 957-630-2 - Long-term toxicity to fish 15/01/2024 29/02/2024 Details
Amides, C16-18 (even numbered), N-C16-18 (even numbered) alkyl 955-212-4 -
Bioaccumulation aquatic / sediment
Sub-chronic toxicity (90-day): oral
04/12/2023
04/12/2023
18/01/2024
18/01/2024
Details
Hydrocarbons, C18-C22, n-alkanes, n-alkenes (Waksol A) 953-917-1 - Reproductive toxicity (pre-natal developmental toxicity) 26/08/2021 11/10/2021 Details
benzenesulfonic acid, 4-c10-13-alkyl derivs.-, salts with amines, c16-c18 (even numbered) alkyl 953-378-2 - Long-term toxicity to fish 30/09/2021 15/11/2021 Details
Esterification products of fatty acids, C18 (unsaturated) alkyl and adipic acid with pentaerythritol 952-795-7 - Long-term toxicity to fish 03/11/2023 18/12/2023 Details
Reaction mass of Ethanaminium, 2-hydroxy-N,N-dimethyl-N-[2-[(1-oxooctadecyl)oxy]ethyl]-, chloride and Ethanaminium, N,N-dimethyl-2-[(1-oxohexadecyl)oxy]-N-[2-[(1-oxooctadecyl)oxy]ethyl]-, chloride 951-974-7 - Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Ethanaminium, 2-hydroxy-N-(2-hydroxyethyl)-N,N-dimethyl-, esters with C16-18 and C18-unsatd. fatty acids, chlorides (EC 620-174-7) 23/11/2020 07/01/2021 Details
Fuels, diesel, co-processed with hydrocarbons derived from thermally cracked waste plastics 951-495-3 -
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Gas oils (petroleum), light vacuum (EC 265-059-9)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with
- Gas oils (petroleum), light vacuum (EC 265-059-9)
- Fuel oil, no. 4 (EC 270-673-5)
- Distillates (petroleum), light hydrocracked (EC 265-078-2)
- Fuels, diesel (EC 269-822-7)
24/08/2020
24/08/2020
08/10/2020
08/10/2020
Details
N1,N3‐bis(3‐methylphenyl)‐5‐[(3‐methylphenyl)sulfamoyl]benzene‐1,3‐dicarboxamide 951-483-8 2375645-78-4
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/06/2022
16/06/2022
16/06/2022
01/08/2022
01/08/2022
01/08/2022
Details
Reaction mass of dipotassium 2-(3,4-dimethyl-1H-pyrazol-1-yl) succinate and dipotassium 2-(4,5-dimethy-1H-pyrazol-1-yl) succinate 950-225-1 -
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Reaction mass of 2-(3,4-dimethyl-1H-pyrazol-1-yl)succinic acid and 2-(4,5-dimethyl-1H-pyrazol-1-yl)succinic acid (EC number 940-877-5, CAS number 2241455-89-8)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Reaction mass of 2-(3,4-dimethyl-1H-pyrazol-1-yl)succinic acid and 2-(4,5-dimethyl-1H-pyrazol-1-yl)succinic acid (EC number 940-877-5, CAS number 2241455-89-8)
17/12/2019
17/12/2019
31/01/2020
31/01/2020
Details
Saccharomyces cerevisiae cell wall, extracted 949-711-6 -
Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Saccharomyces cerevisiae, lysate (EC 305-230-8)
Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with Saccharomyces cerevisiae, lysate (EC 305-230-8)
25/11/2021
25/11/2021
10/01/2022
10/01/2022
Details
Rectified Hydrocarbons by-products from synthetic process of Turpentine and acid, alcohols fraction 949-141-8 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
21/01/2021
21/01/2021
08/03/2021
08/03/2021
Details
Hydrocarbons, C16-C18, isoalkanes,<2% aromatics 948-766-3 - Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2019 15/04/2019 Details
pentasodium 4-amino-3-[{4-[(2,4-disulfonatophenyl)diazenyl]-3-methylphenyl}diazenyl]-5-hydroxy-6-[(4-nitro-2-sulfonatophenyl)diazenyl]naphthalene-1,7-disulfonate 948-569-2 - Genetic toxicity in vivo 01/04/2022 16/05/2022 Details
Fatty acids, C14-C18 and C18 unsaturated, amides with 2,2’-iminodiethanol 948-052-1 - Reproductive toxicity (extended one-generation reproductive toxicity study) 21/01/2021 08/03/2021 Details
Reaction mass of N,N,N',N'-tetrabutylmethylenediamine and dibutylamine 948-040-6 - Genetic toxicity in vivo || Note: Link to registration dossier not given as the dossier not yet disseminated. || Note: Testing proposal is based on concern identified by the registrant. 24/01/2019 11/03/2019 Details
Terpenic base 947-968-9 - Genetic toxicity in vivo 18/03/2021 03/05/2021 Details
2-propenoic acid, butyl ester, reaction products with butadiene and sulfur 947-895-2 -
Bioaccumulation aquatic / sediment
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/01/2024
15/01/2024
15/01/2024
15/01/2024
29/02/2024
29/02/2024
29/02/2024
29/02/2024
Details
C18 unsaturated fatty acids, reaction products with 1-aminopropan-2-ol, maleic anhydride and sodium bisulfite 947-655-7 - Long-term toxicity to fish||Note: testing proposed with disodium 4-[1-methyl-2-[(1-oxooctadec-9-enyl)amino]ethyl] 2-sulphonatosuccinate (EC no. 267-199-6) 15/01/2024 29/02/2024 Details
Phosphoric acid, C11-14 (C13-rich)-isoalkyl mono- and di-esters, partially salted with 1-Propanamine, 3-(tridecyloxy)-, branched 947-480-6 - Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposal is based on concern identified by the registrant 19/10/2020 03/12/2020 Details
Reaction products of diazotised 3-amino-2-hydroxy-5-nitrobenzenesulphonic acid, coupled with 1,3-diaminobenzene and diazotised sodium 4-aminobenzenesulfonate, metallized with Basic Chromium (III) Sulphate, sodium salts 947-395-4 - Genetic toxicity in vivo 18/03/2021 03/05/2021 Details
Fatty acids, C12-18 (even numbered)-methyl esters, sulfonated, sodium salts 947-394-9 -
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
19/10/2020
19/10/2020
19/10/2020
03/12/2020
03/12/2020
03/12/2020
Details
Sodium salts of [hexane-1,6-diylbis[nitrilobis(methylene)]]tetrakisphosphonic acid (4-7 Na:1) 947-369-2 -
Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Potassium salts of {hexane-1,6-iylbis[nitrilobis(methylene)]}tetrakisphosphonic acid (4-7:1); EC 701-184-1

|| Note: Testing proposal is based on concern identified by the registrant.
Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with Potassium salts of {hexane-1,6-iylbis[nitrilobis(methylene)]}tetrakisphosphonic acid (4-7:1); EC 701-184-1

|| Note: Testing proposal is based on concern identified by the registrant.
27/01/2020
27/01/2020
12/03/2020
12/03/2020
Details
Condensation products of phenol and salicylaldehyde 947-320-5 - Genetic toxicity in vivo 20/05/2021 05/07/2021 Details
Reaction mass of disodium (sulphonatothio)acetate and sodium chloride 947-115-0 - Genetic toxicity in vivo 17/06/2020 03/08/2020 Details
Reaction products of diazotised Sodium Picramate coupled with Resorcinol, subsequently coupled with diazotised 4'-Amino-4-Nitrodiphenylamin-2-Sulfonic Acid, at the end metallized with Iron (II) sulphate heptahydrate, sodium salts 946-788-8 - Genetic toxicity in vivo 18/03/2021 03/05/2021 Details
Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C11-17 and C17 unsatd. alkyl) derivs. and sodium hydroxide and 2-propenoic acid 946-533-0 - Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid (EC 931-291-0) 23/04/2018 07/06/2018 Details
Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C11-17 and C17 unsatd. alkyl) derivs. and sodium hydroxide and 2-propenoic acid 946-533-0 - Sub-chronic toxicity (90-day): oral || Note: testing proposed with β-Alanine, N-(2-aminoethyl)-N-(2-hydroxyethyl)-, N-coco acyl derivs., monosodium salts (EC 298-632-7) 16/12/2020 01/02/2021 Details
Reaction mass of 6-Chloro-2-{4[ethyl(2-hydroxyethyl)amino]phenyl}-1-methylbenzo[cd]indolium hydroxide and 6-chloro-2-[4-[ethyl(2-hydroxyethyl)amino]phenyl]-1-methylbenz[cd]indolium acetate 946-378-9 - Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant 16/12/2020 01/02/2021 Details
Hydrocarbons, C9-C10, aromatics, >1% naphthalene 946-365-8 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
21/01/2021
21/01/2021
21/01/2021
08/03/2021
08/03/2021
08/03/2021
Details
Essential oil of Spearmint obtained from the aerial part of Mentha spicata and/or Mentha cardiaca (Lamiaceae) obtained by distillation 946-253-9 - Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant 19/10/2020 03/12/2020 Details
Reaction mass of 3,5,6,6-tetramethyl-4-methyleneheptan-2-one and (E)-3,4,5,6,6-pentamethylhept-3-en-2-one 946-245-5 - Reproductive toxicity (pre-natal developmental toxicity) 06/06/2023 21/07/2023 Details
1,4-Benzenedicarboxylic acid, mixed Bu and 2-ethylhexyl diesters 946-149-3 1571954-81-8
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
21/05/2018
21/05/2018
05/07/2018
05/07/2018
Details
Reaction mass of trisodium [μ-[4-[[3,3'-dihydroxy-4'-[(2-hydroxy-6-sulpho-1-naphthyl)azo][1,1'-biphenyl]-4-yl]azo]-3-hydroxynaphthalene-2,7-disulphonato(7-)]]dicuprate(3-) and triammonium [μ-[4-[[3,3'-dihydroxy-4'-[(2-hydroxy-6-sulpho-1-naphthyl)azo][1,1'-biphenyl]-4-yl]azo]-3-hydroxynaphthalene-2,7-disulphonato(7-)]]dicuprate(3-) 945-577-8 - Sub-chronic toxicity (90-day): oral 01/07/2021 16/08/2021 Details
Alkanoic acid and polyoxomolybdate borate alkanoate clusters 944-813-7 - Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant 24/08/2020 08/10/2020 Details
Reaction mass of Disodium dihydroxy[3-(hydroxy-kO)-4-{[5-(hydroxy-kO)-3-methyl-1-phenyl-1Hpyrazol-4-yl]diazenyl-kN1}naphthalene-1-sulfonato(3-)]chromate(2-) and sodium [4-[(4,5-dihydro-3-methyl-5-oxo-1-phenyl-1H-pyrazol-4-yl)azo]-3-hydroxynaphthalene-1-sulphonato(3-)]hydroxychromate(1-) 944-272-7 - Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant 19/10/2020 03/12/2020 Details
[No public or meaningful name is available] 944-258-0 1850357-57-1 Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Wax, rice bran, oxidized (Polar modified Rice Bran Wax) 03/05/2023 19/06/2023 Details
Reaction mass of N-butylphthalimide and N-sec-butylphthalimide and N-propylphthalimide 943-947-3 - Genetic toxicity in vivo 19/10/2020 03/12/2020 Details
A dried sludge product resulting from the treatment process of domestic wastewater. The exact processes followed for the production of the dried sludge are: Preliminary and secondary treatment of the wastewater stream, thickening, dehydration and drying of the excess sludge. 943-834-9 -
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
03/04/2023
03/04/2023
03/04/2023
22/05/2023
22/05/2023
22/05/2023
Details
Reaction mass of C18 (unsatd.) fatty acid amides/esters of diethanolamine, C16-18 (even-numbered) fatty amine (..) 943-172-0 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
17/05/2016
17/05/2016
17/05/2016
01/07/2016
01/07/2016
01/07/2016
Details
Reaction mass of trientine and trientine, mono- and di-propoxylated 942-835-1 - Genetic toxicity in vivo||Note: testing proposed with [Amines, polyethylenepoly-, triethylenetetramine fraction] (EC no. 292-588-2) 03/10/2023 17/11/2023 Details
Fatty acids, C12-14, α-sulfo, disodium salts 942-523-5 -
Long-term toxicity to fish (OECD 212 – Registrant’s preference)
Reproductive toxicity (pre-natal developmental toxicity) on rodents
Sub-chronic toxicity (90-day): oral on rodents
25/06/2019
25/06/2019
25/06/2019
09/08/2019
09/08/2019
09/08/2019
Details
Fatty acids, C12-14, α-sulfo, disodium salts 942-523-5 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
02/11/2018
02/11/2018
17/12/2018
17/12/2018
Details
plastic, waste, pyrolized, fractionation bottoms (raw diesel) 942-177-5 - Genetic toxicity in vivo 10/05/2022 27/06/2022 Details
N-Phenyl-diethanolamine, reaction products with formaldehyde 942-131-4 - Genetic toxicity in vivo 26/08/2021 11/10/2021 Details
N-Phenyl-diethanolamine, reaction products with formaldehyde 942-131-4 - Reproductive toxicity (pre-natal developmental toxicity) 21/10/2021 07/12/2021 Details
Sophorolipids: fermentation products of glucose and fatty acids, C18 (unsaturated), glycerol esters with yeast Candida Bombicola, partially hydrolysed 941-809-7 - Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposal is based on concern identified by the registrant. 24/07/2019 09/09/2019 Details
Petroleum diesel/gas oil fraction, co-processed with renewable hydrocarbons derived from thermally cracked plastics 941-803-4 -
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with Gas oils (petroleum), light vacuum (EC no. 265-059-9)
Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Gas oils (petroleum), light vacuum (EC no. 265-059-9) ||Note: testing proposed with Fuels, diesel (EC no. 269-822-7) ||Note: testing proposed with Fuel oil, no. 4 (EC no. 270-673-5) ||Note: testing proposed with Distillates (petroleum), light hydrocracked (EC no. 265-078-2)
Sub-chronic toxicity (90-day): oral||Note: testing proposed with Gas oils (petroleum), light vacuum (EC no. 265-059-9)
26/10/2022
26/10/2022
26/10/2022
12/12/2022
12/12/2022
12/12/2022
Details
2-Propyn-1-ol, reaction product with 1-2.5 moles of oxirane 941-793-1 - Reproductive toxicity (pre-natal developmental toxicity) 26/04/2019 10/06/2019 Details
2-Propyn-1-ol, reaction product with 1-2.5 moles of oxirane 941-793-1 - Sub-chronic toxicity (90-day): oral || Note: testing proposed with 2-Propyn-1-ol, compd. with methyloxirane (EC 609-530-2, CAS 38172-91-7) 17/04/2015 04/06/2015 Details
1,3-Butanediol, reaction products with 1,1'-methylenebis[4-isocyanatobenzene], propylene glycol and tripropylene glycol 941-496-7 1689576-89-3 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC 202-966-0) 01/04/2022 16/05/2022 Details
Fatty acids, tall-oil, di- and triesters with trimethylolpropane 941-376-4 -
Long-term toxicity to aquatic invertebrates
Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates.
Testing proposed with EC No 931-531-4.
31/05/2016
31/05/2016
31/05/2016
15/07/2016
15/07/2016
15/07/2016
Details
3-methyldecane; benzene; cyclooctane; nonane 941-364-9 - Reproductive toxicity (extended one-generation reproductive toxicity study) 05/07/2018 20/08/2018 Details
Reaction mass of 2,2'-{methylenebis[(2,6-dimethyl-4,1-phenylene)oxymethylene]}dioxirane and 1,3-bis{4-[3,5-dimethyl-4-(oxiran-2-ylmethoxy)benzyl]-2,6-dimethylphenoxy}propan-2-ol and 3,3'-{methylenebis[(2,6-dimethyl-4,1-phenylene)oxy]}bis(1-{4-[3,5-dimethyl-4-(oxiran-2-ylmethoxy)benzyl]-2,6-dimethylphenoxy}propan-2-ol) 941-357-0 - Reproductive toxicity (extended one-generation reproductive toxicity study) 21/10/2019 05/12/2019 Details
Reaction mass of 2-[[4-[[3,5-dimethyl-4-(oxiran-2-ylmethoxy)phenyl]methyl]-2,6-dimethyl-phenoxy]methyl]oxirane and 1,3-bis[4-[[3,5-dimethyl-4-(oxiran-2-ylmethoxy)phenyl]methyl]-2,6-dimethyl-phenoxy]propan-2-ol and 1-[4-[[3,5-dimethyl-4-(oxiran-2-ylmethoxy)phenyl]methyl]-2,6-dimethyl-phenoxy]-3-[4-[[4-[3-[4-[[3,5-dimethyl-4-(oxiran-2-ylmethoxy)phenyl]methyl]-2,6-dimethyl-phenoxy]-2-hydroxy-propoxy]-3,5-dimethyl-phenyl]methyl]-2,6-dimethyl-phenoxy]propan-2-ol 941-357-0 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
08/02/2017
08/02/2017
27/03/2017
27/03/2017
Details
Hexanoic acid, 3,5,5-trimethyl-, 2,2,6,6-tetramethyl-1-[2-[(3,5,5-trimethyl-1-oxohexyl)oxy]ethyl]-4-piperidinyl ester 941-267-1 1445870-18-7
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
31/01/2023
31/01/2023
31/01/2023
17/03/2023
17/03/2023
17/03/2023
Details
Cashew (Anacardium occidentale) Nutshell Extract, Decarboxylated 941-216-3 -
Bioaccumulation aquatic / sediment || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Testing proposal is based on concern identified by the registrant.
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Testing proposal is based on concern identified by the registrant.
Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Testing proposal is based on concern identified by the registrant.
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Testing proposal is based on concern identified by the registrant.
15/07/2014
15/07/2014
15/07/2014
15/07/2014
29/08/2014
29/08/2014
29/08/2014
29/08/2014
Details
Cashew (Anacardium occidentale) Nutshell Extract, Decarboxylated, Distillation Residue 941-212-1 -
Bioaccumulation aquatic / sediment || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade).
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade).
Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Testing proposal is based on concern identified by the registrant.
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade).
15/07/2014
15/07/2014
15/07/2014
15/07/2014
29/08/2014
29/08/2014
29/08/2014
29/08/2014
Details
3-{[3-(C10-16-oxy)propyl]amino}propan-1-aminium acetate 941-152-6 - Sub-chronic toxicity (90-day): oral||Note: testing proposed with 1,3-propanediamine, N-[3-((C11-14, C13-rich)oxy)propyl]-branched acetate (EC: 931-295-2) 15/07/2022 29/08/2022 Details
Reaction mass of 2-(3,4-dimethyl-1H-pyrazol-1-yl)succinic acid and 2-(4,5-dimethyl-1H-pyrazol-1-yl)succinic acid 940-877-5 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
29/03/2019
29/03/2019
13/05/2019
13/05/2019
Details
Bis(2-chloroethoxy)methane 1,15-dichloro-3,5,8,11,13-penta-oxa pentadecane 1-(2-chloroethoxy)-2-(2-chloroethoxymethoxy)ethane 940-783-4 -
Genetic toxicity in vivo
Long-term toxicity to fish
Reproductive toxicity (two-generation reproductive toxicity) // Note: test to be performed with analogues substance 1-chloro-2-[(2-chloroethoxy)methoxy]ethane (EC 203-920-2 )
02/06/2014
02/06/2014
02/06/2014
17/07/2014
17/07/2014
17/07/2014
Details
reaction mass of bis(2,3-epoxypropyl) terephthalate and tris(oxiranylmethyl) benzene-1,2,4-tricarboxylate 940-592-6 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity) || Note: Testing proposal is based on concern identified by the registrant
Sub-chronic toxicity (90-day): oral
16/02/2015
16/02/2015
16/02/2015
02/04/2015
02/04/2015
02/04/2015
Details
Fatty acids, tall oil and rosin reacted with maleic anhydride 940-281-5 -
Reproductive toxicity (pre-natal developmental toxicity) //Note:testing to be done with rosin maleated (CAS 8050-28-0)
Sub-chronic toxicity (90-day): oral. //Note:testing to be done with rosin maleated (CAS 8050-28-0)
18/02/2014
18/02/2014
04/04/2014
04/04/2014
Details
Bis[C5-(branched)-alkyl]l benzene-1,4-dicarboxylate   940-272-6 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity
Sub-chronic toxicity (90-day): oral
01/09/2017
01/09/2017
01/09/2017
16/10/2017
16/10/2017
16/10/2017
Details
Nonanoic acid (branched), 2-oxiranylmethyl ester 940-029-4 -
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 2,3-epoxypropyl neodecanoate (EC No. 247-979-2)
Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with 2,3-epoxypropyl neodecanoate (EC No. 247-979-2)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with 2,3-epoxypropyl neodecanoate (EC No. 247-979-2)
20/09/2013
20/09/2013
20/09/2013
04/11/2013
04/11/2013
04/11/2013
Details
Reaction Mass of Cis-4-(isopropyl) cyclohexanemethanol and Trans-4-(isopropyl) cyclohexanemethanol 939-719-8 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
02/06/2014
02/06/2014
17/07/2014
17/07/2014
Details
calcium bis(di C8-C10, branched, C9 rich, alkylnaphthalenesulphonate) 939-717-7 - Sub-chronic toxicity (90-day): oral 02/06/2014 17/07/2014 Details
Reaction mass of ethoxylated (= 3 moles) bisphenol A dimethacrylate and (1-methylethylidene)bis(4,1-phenyleneoxy-2,1-ethanediyl) bismethacrylate 939-702-5 - Long-term toxicity to fish 25/11/2019 09/01/2020 Details
Reaction mass of ethoxylated (≥ 3 moles) bisphenol A dimethacrylate and (1-methylethylidene)bis(4,1-phenyleneoxy-2,1-ethanediyl) bismethacrylate 939-702-5 -
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Ethoxylated bisphenol A diacrylate
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Ethoxylated bisphenol A diacrylate
12/12/2014
12/12/2014
26/01/2015
26/01/2015
Details
N,N-bis(2-ethylhexyl)-5-methyl-1H-benzotriazole-1-methylamine, N,N-bis(2-ethylhexyl)-4-methyl-1H-benzotriazole-1-methylamine, 2H-Benzotriazole-2-methanamine, N,N-bis(2-ethylhexyl)-4-methyl-, 2H-Benzotriazole-2-methanamine, N,N-bis(2-ethylhexyl)-5-methyl-, 1H-Benzotriazole-1-methanamine, N,N-bis(2-ethylhexyl)-6-methyl-(Mixture) 939-700-4 - Sub-chronic toxicity (90-day): oral 21/10/2019 05/12/2019 Details
Butanoic acid, 4-amino-4-oxo-2(or 3)-sulfo-,N-(C16-C18 (even numbered), C18 unsaturated alkyl)), disodium salts 939-691-7 - Reproductive toxicity (pre-natal developmental toxicity) 17/09/2019 01/11/2019 Details
N,N-dimethyl-alkyl-1-amines, reaction products with alkali hydroxide and chloroacetic acid 939-682-8 -
Long-term toxicity to fish
Reproductive toxicity (extended one-generation reproductive toxicity study)
10/05/2022
10/05/2022
27/06/2022
27/06/2022
Details
Reaction mass of 1-(C12-18-(even numbered))-alkyl-tetrahydropyrimidin-2(1H)-imine acetate salt and 1-(3-((C12-18-(even numbered))-alkyl-amino)propyl)guanidine acetate salt and 1-(C12-18-(even numbered))-alkyl-1-(3-guanidinopropyl)guanidine acetate salt 939-650-3 - Sub-chronic toxicity (90-day): oral 10/05/2022 27/06/2022 Details
Reaction mass of 1-(C12-18-(even numbered))-alkyl-tetrahydropyrimidin-2(1H)-imine acetate salt and 1-(3-((C12-18-(even numbered))-alkyl-amino)propyl)guanidine acetate salt and 1-(C12-18-(even numbered))-alkyl-1-(3-guanidinopropyl)guanidine acetate salt 939-650-3 - Reproductive toxicity (pre-natal developmental toxicity) 14/08/2014 28/09/2014 Details
Distilled tall oil, magnesium salts 939-629-9 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
30/11/2015
30/11/2015
14/01/2016
14/01/2016
Details
Hydrocarbons, C14-C17, isoalkanes, cyclics, <2% aromatics 939-601-6 - Reproductive toxicity (two-generation reproductive toxicity) // Note: testing proposed with Icosane (C20 normal alkanes); Hydrocarbons, C14-C19, isoalkane, cyclics, < 2%; Hydrocarbon, C16-C20, normal, isoalkane, cyclics, 2-30% aromatics 02/06/2014 17/07/2014 Details
Reaction mass of potassium ethyl octylphosphonate and diethyl octylphosphonate 939-595-5 - Reproductive toxicity (pre-natal developmental toxicity) 17/04/2015 04/06/2015 Details
Reaction Products of alcohols, C14-18, C18 unsat., esterified with phosphorus pentoxide and salted with amines, C12-14,-tert-alkyl 939-591-3 - Reproductive toxicity (pre-natal developmental toxicity) 15/04/2014 30/05/2014 Details
3-C12-18-(even numbered)-alkylamido-N,N-dimethylpropan-1-amino oxide 939-581-9 - Reproductive toxicity (pre-natal developmental toxicity) 26/03/2018 11/05/2018 Details
Reaction mass of Ammonium bisethanedioato bisaquo niobate(V) (anhydrous form) and Ammonium hydrogen ethanedioate ethanedioic acid (anhydrous form 939-559-9 - Reproductive toxicity (pre-natal developmental toxicity) 01/09/2017 16/10/2017 Details
Fatty acid chlorides, C18 unsatd., reaction products with sodium N-methyltaurinate 939-538-4 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
04/04/2014
04/04/2014
19/05/2014
19/05/2014
Details
Reaction mass of [[(2-hydroxyethyl)imino]dimethylene]bisphosphonic acid, sodium salt and 4-(Phosphonomethyl)-2-hydroxy-2-oxo-1,4,2-oxazaphosphorinane, sodium salt 939-513-8 -
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed either the registered substance or a read-across substance, which would be the acid form of the registered substance
Sub-chronic toxicity (90-day): oral
Note: testing proposed either the registered substance or a read-across substance, which would be the acid form of the registered substance
25/06/2015
25/06/2015
10/08/2015
10/08/2015
Details
Reaction product of 2,4-Dinitrotoluene and 2,6-Dinitrotoluene and hydrogen 939-489-9 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): oral
02/06/2014
02/06/2014
17/07/2014
17/07/2014
Details
Reaction product of 2,4-Dinitrotoluene and 2,6-Dinitrotoluene and hydrogen 939-489-9 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
18/02/2021
18/02/2021
05/04/2021
05/04/2021
Details
3-((C9-11-iso,C10-rich)alkyloxy)propan-1-amine 939-485-7 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
02/06/2014
02/06/2014
17/07/2014
17/07/2014
Details
Reaction products of tryglycerides, C8-C18 (even numbered) and C18-unsaturated, glycerine and ethylene oxide 939-459-5 - Sub-chronic toxicity (90-day): oral 30/11/2015 14/01/2016 Details
1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C12-18(even numbered) acyl) derivs., hydroxides, inner salts 939-457-4 -
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/09/2014
18/09/2014
18/09/2014
03/11/2014
03/11/2014
03/11/2014
Details
1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C8-18(even numbered) acyl) derivs., hydroxides, inner salts 939-455-3 -
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): oral
18/09/2014
18/09/2014
18/09/2014
03/11/2014
03/11/2014
03/11/2014
Details
3-((C9-11-iso,C10-rich)alkyloxy)propan-1-amine acetate (1:1) 939-448-5 -
Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposed with 1-Propanamine, 3-((C9-11-iso-,C10-rich)alkyloxy)-
Sub-chronic toxicity (90-day): oral || Note: Testing proposed with 1-Propanamine, 3-((C9-11-iso-,C10-rich)alkyloxy)-
02/06/2014
02/06/2014
17/07/2014
17/07/2014
Details
Reaction mass of (2S-cis)-tetrahydro-4-methyl-2-(2-methyl-1-propenyl)-2H-pyran and Tetrahydro-4-methyl-2-(2-methylpropen-1-yl)pyran (2R,4R) and Tetrahydro-4-methyl-2-(2-methylpropen-1-yl)pyran (2S,4S) and (2R-cis)-tetrahydro-4-methyl-2-(2-methyl-1-propenyl)-2H-pyran 939-429-1 16409-43-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
30/11/2015
30/11/2015
14/01/2016
14/01/2016
Details
Fatty acids, tall-oil, reaction products with acrylic acid 939-424-4 - Long-term toxicity to fish 04/04/2014 19/05/2014 Details
2-Oxetanone, 3-C12-16-alkyl-4-C13-17-alkylidene derivs., (4E)- 939-401-9 1469983-41-2 Long-term toxicity to fish ||Note: testing proposed with 2-Oxetanone, 3-C14-16-alkyl 4-C15-17-alkylidene derivs (EC no. 308-760-8) 15/07/2022 29/08/2022 Details
Reaction products of diazotised 4,4-diaminodiphenylamine-2-sulfonic acid, subsequently coupled with 6-amino-4-hydroxynaphthalene-2-sulfonic acid, further diazotised and coupled with metaphenylendiamine, sodium salts 939-382-7 - Genetic toxicity in vivo 25/11/2021 10/01/2022 Details
Nickel, 5,5'-azobis-2,4,6(1H,3H,5H)-pyrimidinetrione complexes and melamine 939-379-0 - Reproductive toxicity (pre-natal developmental toxicity) 04/04/2014 19/05/2014 Details
Reaction product of naphthalene, propan-2-ol, sulfonated and neutralized by caustic soda 939-368-0 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): inhalation
17/06/2014
17/06/2014
01/08/2014
01/08/2014
Details
Reaction mass of sodium hydrogen N-(1-oxooctadecyl)-L-glutamate and stearic acid 939-201-1 - Reproductive toxicity (pre-natal developmental toxicity) 25/06/2015 10/08/2015 Details
Reaction mass of 4-tert-butylphenol and 1,3- phenylenedimethanamine and 2-({[3-(aminomethyl) benzyl]amino}methyl)-4-tert-butylphenol 939-071-6 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
02/07/2013
02/07/2013
16/08/2013
16/08/2013
Details
Reaction mass of 3-isopropyl-6-methylenecyclohexene and (4R)-1-methyl-4-(prop-1-en-2-yl)cyclohexene and (4S)-1-methyl-4-(prop-1-en-2-yl)cyclohexene 939-009-8 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
22/09/2022
22/09/2022
07/11/2022
07/11/2022
Details
Reaction mass of 3-isopropyl-6-methylenecyclohexene and (4R)-1-methyl-4-(prop-1-en-2-yl)cyclohexene and (4S)-1-methyl-4-(prop-1-en-2-yl)cyclohexene 939-009-8 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
01/09/2017
01/09/2017
16/10/2017
16/10/2017
Details
Reaction mass of 3-isopropyl-6-methylenecyclohexene and (4R)-1-methyl-4-(prop-1-en-2-yl)cyclohexene and (4S)-1-methyl-4-(prop-1-en-2-yl)cyclohexene 939-009-8 - Sub-chronic toxicity (90-day): oral 21/12/2021 04/02/2022 Details
Reaction products of n-octanol and acrylic acid, first distillation pitch 938-925-5 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/03/2021
18/03/2021
03/05/2021
03/05/2021
Details
Reaction products of n-octanol and acrylic acid, first distillation pitch 938-925-5 - Long-term toxicity to fish 15/01/2024 29/02/2024 Details
Middle distillate from refinery proces cofeeding vegetable oil 938-793-9 - Reproductive toxicity (two-generation reproductive toxicity) 02/09/2013 18/10/2013 Details
Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C11-C13 odd-numbered alkyl) derivs. and sodium hydroxide and chloroacetic acid 938-645-3 -
Long-term toxicity to fish Note: testing proposed with [Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C11 alkyl) derivs. and sodium hydroxide and chloroacetic acid] (EC 271-794-6)
Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with [Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid] (EC 931-291-0)
Sub-chronic toxicity (90-day): oral Note: testing proposed with [Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid] (EC 931-291-0)
16/03/2015
16/03/2015
16/03/2015
30/04/2015
30/04/2015
30/04/2015
Details
Reaction mass of 2-ethyl-2-(methoxymethyl)-propane-1,3-diol and 2-ethylpropane-1,3-diol 938-572-7 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
06/09/2018
06/09/2018
22/10/2018
22/10/2018
Details
Reaction mass of 2-ethyl-2-(methoxymethyl)-propane-1,3-diol and 2-ethylpropane-1,3-diol 938-572-7 - Long-term toxicity to fish 22/09/2022 07/11/2022 Details
Ashes (residues), nonhazardous municipal solid waste 937-417-0 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
17/08/2012
17/08/2012
01/10/2012
01/10/2012
Details
Ashes (residues), nonhazardous municipal solid waste 937-417-0 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
25/05/2020
25/05/2020
09/07/2020
09/07/2020
Details
Hydrocarbons, C17-C19, n-alkanes, <2% aromatics 937-158-3 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Reaction mass of dibutyl adipate and dibutyl glutarate 936-196-8 -
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Reaction mass of dimethyl adipate, dimethyl glutarate and dimethyl succinate (EC 906-170-0)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Reaction mass of dimethyl adipate, dimethyl glutarate and dimethyl succinate (EC 906-170-0)
16/12/2020
16/12/2020
01/02/2021
01/02/2021
Details
Decene, hydroformylation products, high boiling 935-454-7 -
Reproductive toxicity (pre-natal developmental toxicity) // Note: testing proposed with Alkenes, C11-12, hydroformylation products, distn. residues (CAS: 90622-27-8)
Sub-chronic toxicity (90-day): oral // Note: testing proposed with Alkenes, C11-12, hydroformylation products, distn. residues (CAS: 90622-27-8)
02/06/2014
02/06/2014
17/07/2014
17/07/2014
Details
C26-28 (even numbered) α-alkenes 934-268-3 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
18/06/2012
18/06/2012
18/06/2012
02/08/2012
02/08/2012
02/08/2012
Details
Reaction mass of N-[2-(2-oxoimidazolidin-1-yl)ethyl]methacrylamide and methacrylic acid 934-058-1 -
Genetic toxicity in vivo
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/05/2014
16/05/2014
16/05/2014
16/05/2014
30/06/2014
30/06/2014
30/06/2014
30/06/2014
Details
Slags, steelmaking, elec. furnace (stainless/high alloy steel production) 932-476-9 - Sub-chronic toxicity (90 day): inhalation 06/03/2012 20/04/2012 Details
Alkenes, C11-12, hydroformylation products, low boiling 932-235-8 - Reproductive toxicity (two-generation reproductive toxicity) 16/06/2011 01/08/2011 Details
Reaction mass of Amides, rape-oil, N-(hydroxyethyl), ethoxylated and Glycerol, ethoxylated 932-164-2 -
Long-term toxicity to fish
Sub-chronic toxicity (90-day): oral
29/07/2011
29/07/2011
12/09/2011
12/09/2011
Details
Calcium dihydroxide precipitated with carbon dioxide during sugar juice purification 932-124-4 - Sub-chronic toxicity (90 day): inhalation 01/07/2011 15/08/2011 Details
N-[3-(dimethylamino)propyl] C 12-C18 alkylamide 932-121-8 1147459-12-8
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/09/2014
18/09/2014
03/11/2014
03/11/2014
Details
Reaction mass of p-mentha-1,4-diene and p-mentha-1,3-diene and dipentene and p-mentha-1(7),2-diene and p-mentha-1,4(8)-diene 931-893-3 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
15/09/2011
15/09/2011
31/10/2011
31/10/2011
Details
Reaction mass of Alkenes C20-24 and Alkenes C24-28 931-746-3 93924-10-8
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
03/11/2011
03/11/2011
16/07/2012
19/12/2011
19/12/2011
30/08/2012
Details
Imidazolium compounds, 2-C17-unsatd.-alkyl-1-(2-C18-unsatd. amidoethyl)-4,5-dihydro-N-methyl, Me sulfates 931-745-8 - Sub-chronic toxicity (90-day): oral 01/07/2011 15/08/2011 Details
Amides, C16-C18 (even numbered) 931-695-7 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/08/2011
16/08/2011
30/09/2011
30/09/2011
Details
Reaction mass of bisisopropyl peroxydicarbonate and bis-sec-butyl peroxydicarbonate and isopropyl-sec-butylperoxydicarbonate 931-536-1 - Genetic toxicity in vivo || Note: testing proposed with bisisopropyl peroxydicarbonate EC 203-317-4, CAS 105-64-6 (is a constituent of the multi-constituent registered substance) || Note: Testing proposal is based on concern identified by the registrant 24/08/2020 08/10/2020 Details
Alkenes, C11-12 931-515-7 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
03/11/2011
03/11/2011
25/06/2012
19/12/2011
19/12/2011
09/08/2012
Details
Alkenes, C21-32 linear and branched 931-505-2 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
15/09/2011
15/09/2011
25/06/2012
31/10/2011
31/10/2011
09/08/2012
Details
Alkenes C20+ 931-467-7 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
15/09/2011
15/09/2011
31/10/2011
31/10/2011
Details
Magnesium, bis(2-hydroxybenzoato-O1,O2)-, ar,ar'-di-C14-18alkyl derivs 931-371-5 - Reproductive toxicity (extended one-generation reproductive toxicity study) 23/04/2018 07/06/2018 Details
Activated Carbon - High Density Skeleton 931-328-0 - Sub-chronic toxicity (90 day): inhalation 16/06/2011 01/08/2011 Details
3-C12-14-(even numbered)-alkylamido-N,N-dimethylpropan-1-amino oxide 931-324-9 - Sub-chronic toxicity (90-day): oral 02/09/2011 17/10/2011 Details
Amides, C16-C18 (even) , N,N'-ethylenebis 931-299-4 68390-94-3
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
01/03/2023
01/03/2023
17/04/2023
17/04/2023
Details
Amides, C16-C18 (even) , N,N'-ethylenebis 931-299-4 - Sub-chronic toxicity (90-day): oral 16/08/2011 30/09/2011 Details
1,3-Propanediamine, N-[3-((C11-14, C13-rich)oxy)propyl]- branched acetate 931-295-2 - Sub-chronic toxicity (90-day): oral 25/05/2020 09/07/2020 Details
Reaction mass of 1,3-Propanediamine, N-[3-(tridecyloxy)propyl]-, branched and 1,3-Propanediamine, N-[3-(tridecyloxy)propyl]-, branched acetate 931-295-2 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
15/09/2011
15/09/2011
15/09/2011
31/10/2011
31/10/2011
31/10/2011
Details
Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid 931-291-0 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
23/03/2020
23/03/2020
07/05/2020
07/05/2020
Details
Benzoic acid, 2-hydroxy-, mono-C14-18-alkyl derivs., calcium salts (2:1) 931-276-9 - Reproductive toxicity (extended one-generation reproductive toxicity study) 23/04/2018 07/06/2018 Details
Hydrocarbons, C14-C20, n-alkanes, isoalkanes, <2% aromatics 931-265-9 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Product of Semi-Dry Absorption method of Flue Gas Desulphurization (SDA Product) 931-259-6 -
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
02/09/2011
02/09/2011
17/10/2011
17/10/2011
Details
Ashes from fluidized Bed combustion coal fired Power stations with and without co-combustion of secondary fuels (biomass,other fuels - to be verified in view of ecotoxicological and toxicological tests) 931-257-5 - Reproductive toxicity (pre-natal developmental toxicity) 05/04/2011 20/05/2011 Details
Amorphous glass product formed from the melting and fiberisation of dipotassium oxide, oxo(oxoalumanyloxy)alumane and dioxosilane 931-219-8 - Sub-chronic toxicity (90 day): inhalation 24/05/2013 08/07/2013 Details
Fatty acids, C18 unsatd., reaction products with triethanolamine, di-Me sulfate-quaternized 931-216-1 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
15/03/2011
15/03/2011
29/04/2011
29/04/2011
Details
Reaction products of C18 (unsaturated) fatty acids and dimethyl sulfate and triethanolamine 931-216-1 - Long-term toxicity to fish || Note: testing proposed with Fatty acids, C16-18 (even numbered) and C18 unsatd., reaction products with diethylene triamine, di-Me sulfate quaternized (EC 937-237-2) 22/04/2021 07/06/2021 Details
Fatty acids, C16-18 (even numbered), reaction products with triethanolamine, di-Me sulfate-quaternized 931-209-3 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
15/03/2011
15/03/2011
29/04/2011
29/04/2011
Details
Fatty acids, C16-18 (even numbered) and C18 unsatd., reaction products with triethanolamine, di-Me sulfate-quaternized 931-203-0 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
15/03/2011
15/03/2011
29/04/2011
29/04/2011
Details
Hydrocarbons, C11-C12, isoalkanes, cyclics, <2% aromatics 931-121-5 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Alkenes, C13-14 931-071-4 - Sub-chronic toxicity (90-day): oral 25/06/2012 09/08/2012 Details
Shale oils, heavy 930-690-7 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
17/11/2011
14/03/2016
14/03/2016
02/01/2012
28/04/2016
28/04/2016
Details
Reaction product of Crude sludge and Calcium oxide. Crude sludge is the mixture of by-products of petroleum hydrocarbons refining (especially Total petroleum hydrocarbons, Polycyclic aromatic hydrocarbons, acid-refined heavy petroleum distillates). The Crude sludge is neutralised by calcium oxide in the ratio 80:20. The maturing process proceeds under ambient conditions and takes for at least 3 days. Subsequently, the reaction product is processed mechanically 930-592-4 - Reproductive toxicity (pre-natal developmental toxicity) 20/09/2013 04/11/2013 Details
4'-Ethyl-2,3-difluorbiphenyl-4-boronic acid 929-209-3 - Genetic toxicity in vivo 16/12/2020 01/02/2021 Details
Hydrocarbons, C10-C13, n-alkanes, <2% aromatics 929-018-5 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C13-C18, n-alkanes, isoalkanes, cyclics, <2% aromatics 928-253-0 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Octadecylamine, reaction products with 4,4'-methylenediphenyl diisocyanate 928-226-3 - Sub-chronic toxicity (90-day): oral 16/10/2014 01/12/2014 Details
Hydrocarbons, C8-C12, n-alkanes, isoalkanes, cyclics, aromatics (2-25%) 928-136-4 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Acetalization products between glucose and C16-18(even numbered)- alcohol 927-870-2 - Sub-chronic toxicity (90-day): oral 15/09/2011 31/10/2011 Details
Hydrocarbons, C12-C16, isoalkanes, cyclics, <2% aromatics 927-676-8 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C14-C18, n-alkanes, isoalkanes, cyclics, <2% aromatics 927-632-8 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C9-C10, n-alkanes, isoalkanes, cyclics, aromatics (2-25%) 927-344-2 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C11-C14, isoalkanes, cyclics, <2% aromatics 927-285-2 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C9-C10, n-alkanes, isoalkanes, cyclics, <2% aromatics 927-241-2 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
2,2',6,6'-Tetrabromo-4,4'-isopropylidenediphenol, oligomeric reaction products with Propylene oxide and n-butyl glycidyl ether 926-564-6 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
21/10/2019
21/10/2019
05/12/2019
05/12/2019
Details
Hydrocarbons, C11-C14, n-alkanes, isoalkanes, cyclics, <2% aromatics 926-141-6 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Reaction product of 4,4'-methylenediphenyl diisocyanate (MDI) (101-68-8), Octylamine (111-86-4) and Cyclohexylamine (108-91-8) 926-119-6 - Long-term toxicity to fish || Note: testing proposed with Reaction mass of 4,4'-methylenediphenyl diisocyanate and Amines, soya alkyl (EC 905-837-3) and Reaction product of 4,4'-methylenediphenyl diisocyanate (MDI) (CAS: 101-68-8), Octylamine (111-86-4) and Hexamethylenediamine (124-09-4) (EC no 924-670-7) 30/09/2021 15/11/2021 Details
(Reaction product of 4-[2-(4-hydroxyphenyl)propan-2-yl]phenol, 2-(2-hydroxyethylamino)ethanol and formaldehyde), propoxylated 926-000-9 - Reproductive toxicity (pre-natal developmental toxicity) 04/04/2014 19/05/2014 Details
Hydrocarbons, C9-C11, cyclics, <2% aromatics 925-894-8 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C11-C14, n-alkanes, isoalkanes, cyclics, aromatics (2-25%) 925-653-7 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
1,6-hexanediyl-bis(2-(2-(1-ethylpentyl)-3-oxazolidinyl)ethyl)carbamate 925-259-5 140921-24-0
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/05/2014
16/05/2014
16/05/2014
30/06/2014
30/06/2014
30/06/2014
Details
Hydrocarbons, C11-C14, n-alkanes, <2% aromatics 924-803-9 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Reaction product of 4,4'-methylenediphenyl diisocyanate, Octylamine and Hexamethylenediamine 924-670-7 - Long-term toxicity to fish || Note: testing proposed with Reaction mass of 4,4'-methylenediphenyl diisocyanate and Amines, soya alkyl (EC no. 905-837-3) 16/06/2022 01/08/2022 Details
Acetalization products between glucose and C20-22(even numbered)- alcohol 923-835-0 - Sub-chronic toxicity (90-day): oral 15/09/2011 31/10/2011 Details
Shale oils, light 923-592-0 - Reproductive toxicity (extended one-generation reproductive toxicity study) “|| Note: testing proposed with Shale oils, heavy fraction (Registration No 01-2119756217-35-0000)||” Sub-chronic toxicity (90-day): oral “|| Note: testing proposed with Shale oils, heavy fraction (Registration No 01-2119756217-35-0000)||” 14/03/2016 28/04/2016 Details
Shale oils, light 923-592-0 -
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
17/11/2011
17/11/2011
17/11/2011
02/01/2012
02/01/2012
02/01/2012
Details
Hydrocarbons, C10-C12, isoalkanes, < 2% aromatics 923-037-2 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C10-C13, aromatics, 922-153-0 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
21/01/2021
21/01/2021
21/01/2021
08/03/2021
08/03/2021
08/03/2021
Details
Hydrocarbons, C7-C9, isoalkanes 921-728-3 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
21/01/2021
21/01/2021
21/01/2021
08/03/2021
08/03/2021
08/03/2021
Details
Hydrocarbons, C14-C16, n-alkanes, <2% aromatics 921-535-4 - Reproductive toxicity (extended one-generation reproductive toxicity study) 02/11/2018 17/12/2018 Details
Hydrocarbons, C13-C18, n-alkanes, isoalkanes, cyclics, < 2% aromatics 921-050-8 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
1-(4-(ACETYLOXY)-3-((ACETYLOXY)METHYL)PHENYL)ETHANONE 921-042-4 - Genetic toxicity in vivo 25/05/2020 09/07/2020 Details
Hydrocarbons, C11-C13, isoalkanes, <2% aromatics 920-901-0 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C14-C18, n-alkanes, isoalkanes, cyclics, aromatics (2-30 %) 920-360-0 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C10-C14, n-alkanes, isoalkanes, <2% aromatics 920-274-3 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C9-C11, isoalkanes, cyclics 920-134-1 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
21/01/2021
21/01/2021
21/01/2021
08/03/2021
08/03/2021
08/03/2021
Details
Hydrocarbons, C9-C11, isoalkanes, cyclics, <2% aromatics 920-134-1 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C14-C19, isoalkanes, cyclics, <2% aromatics 920-114-2 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
21/01/2021
21/01/2021
21/01/2021
08/03/2021
08/03/2021
08/03/2021
Details
Hydrocarbons, C14-C19, isoalkanes, cyclics, <2% aromatics 920-114-2 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C12-C15, n-alkanes, isoalkanes, cyclics, < 2% aromatics 920-107-4 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C9-C11, n-alkanes, isoalkanes, cyclics, <2% aromatics 919-857-5 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Esterification products of 4,4'-Isopropylidenediphenol, ethoxylated and prop-2-enoic acid and 3,5,5-trimethylhexanoic acide 919-846-5 -
Reproductive toxicity (pre-natal developmental toxicity)
Note: testing proposed with an analogous substance
Sub-chronic toxicity (90-day): oral
31/08/2015
31/08/2015
15/10/2015
15/10/2015
Details
Hydrocarbons, C9-C12, n-alkanes, isoalkanes, cyclics, aromatics (2-25%) 919-446-0 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C10-C13, n-alkanes, isoalkanes, cyclics, aromatics (2-25%) 919-164-8 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C10-C13, n-alkanes, isoalkanes, cyclics, aromatics (2-25%) 919-164-8 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
21/01/2021
21/01/2021
21/01/2021
08/03/2021
08/03/2021
08/03/2021
Details
Hydrocarbons, C16-C20, n-alkanes, isoalkanes, cyclics, <2% aromatics 919-029-3 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C16-C20, n-alkanes, isoalkanes, cyclics, aromatics (2-30 %) 919-006-8 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
21/01/2021
21/01/2021
21/01/2021
08/03/2021
08/03/2021
08/03/2021
Details
Hydrocarbons, C16-C20, n-alkanes, isoalkanes, cyclics, aromatics (2-30 %) 919-006-8 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C13-C16, isoalkanes, cyclics, <2% aromatics 918-973-3 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C10-C13, n-alkanes, isoalkanes, cyclics, < 2% aromatics 918-481-9 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C10-C13, isoalkanes, cyclics, <2% aromatics 918-317-6 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C11-C12, isoalkanes, < 2% aromatics 918-167-1 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C14-C17, n-alkanes, <2% aromatics 917-828-1 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Hydrocarbons, C14-C17, n-alkanes, <2% aromatics 917-828-1 - Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with two substances in a group: Icosane (EC 204-018-1) and Hydrocarbons, C14-C19, isoalkanes, cyclics, < 2% aromatics (920-114-2) 02/11/2018 17/12/2018 Details
Hydrocarbons, C13-C15, n-alkanes, isoalkanes, cyclics, < 2% aromatics 917-488-4 - Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Reaction mass of 2,7-Naphthalenedisulfonic acid, 5-amino-3-[[4-[2-[4-[(7-amino-1-hydroxy-3-sulfo-2-naphthalenyl)azo]-2-sulfophenyl]ethenyl]-3-sulfophenyl]azo]-4-hydroxy-, compd. with 2,2',2''-nitrilotris[ethanol] (1:5) and 3,3'-[ethylenebis[(3-sulpho-p-phenylene)azo]]bis[5-amino-4-hydroxynaphthalene-2,7-disulphonic] acid, compound with 2,2',2''-nitrilotriethanol (1:6) and 3,3'-[vinylenebis[(3-sulpho-p-phenylene)azo]]bis[6-amino-4-hydroxynaphthalene-2-sulphonic] acid, compound with 2,2',2''-nitrilotriethanol (1:4) 916-899-6 - Sub-chronic toxicity (90-day): oral 10/08/2018 24/09/2018 Details
Reaction products of tetrazotized 5-amino-2-[(E)-2-(4-amino-2-sulfophenyl)ethenyl]benzenesulfonic acid with 6-amino-4-hydroxynaphthalene-2-sulfonic acid and 4-amino-5-hydroxynaphthalene-2,7-disulfonic acid in 2-[bis(2-hydroxyethyl)amino]ethanol 916-899-6 - Genetic toxicity in vivo 16/12/2020 01/02/2021 Details