Previous Testing Proposals
Previous Testing Proposals
Previous Testing Proposals
This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.
To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.
Trimethylolpropane and its reaction products with methyloxirane | 957-630-2 | - | Long-term toxicity to fish | 15/01/2024 | 29/02/2024 | Details | |
Amides, C16-18 (even numbered), N-C16-18 (even numbered) alkyl | 955-212-4 | - |
Bioaccumulation aquatic / sediment Sub-chronic toxicity (90-day): oral |
04/12/2023 04/12/2023 |
18/01/2024 18/01/2024 |
Details | |
Hydrocarbons, C18-C22, n-alkanes, n-alkenes (Waksol A) | 953-917-1 | - | Reproductive toxicity (pre-natal developmental toxicity) | 26/08/2021 | 11/10/2021 | Details | |
benzenesulfonic acid, 4-c10-13-alkyl derivs.-, salts with amines, c16-c18 (even numbered) alkyl | 953-378-2 | - | Long-term toxicity to fish | 30/09/2021 | 15/11/2021 | Details | |
Esterification products of fatty acids, C18 (unsaturated) alkyl and adipic acid with pentaerythritol | 952-795-7 | - | Long-term toxicity to fish | 03/11/2023 | 18/12/2023 | Details | |
Reaction mass of Ethanaminium, 2-hydroxy-N,N-dimethyl-N-[2-[(1-oxooctadecyl)oxy]ethyl]-, chloride and Ethanaminium, N,N-dimethyl-2-[(1-oxohexadecyl)oxy]-N-[2-[(1-oxooctadecyl)oxy]ethyl]-, chloride | 951-974-7 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Ethanaminium, 2-hydroxy-N-(2-hydroxyethyl)-N,N-dimethyl-, esters with C16-18 and C18-unsatd. fatty acids, chlorides (EC 620-174-7) | 23/11/2020 | 07/01/2021 | Details | |
Fuels, diesel, co-processed with hydrocarbons derived from thermally cracked waste plastics | 951-495-3 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with Gas oils (petroleum), light vacuum (EC 265-059-9) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with - Gas oils (petroleum), light vacuum (EC 265-059-9) - Fuel oil, no. 4 (EC 270-673-5) - Distillates (petroleum), light hydrocracked (EC 265-078-2) - Fuels, diesel (EC 269-822-7) |
24/08/2020 24/08/2020 |
08/10/2020 08/10/2020 |
Details | |
N1,N3‐bis(3‐methylphenyl)‐5‐[(3‐methylphenyl)sulfamoyl]benzene‐1,3‐dicarboxamide | 951-483-8 | 2375645-78-4 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/06/2022 16/06/2022 16/06/2022 |
01/08/2022 01/08/2022 01/08/2022 |
Details | |
Reaction mass of dipotassium 2-(3,4-dimethyl-1H-pyrazol-1-yl) succinate and dipotassium 2-(4,5-dimethy-1H-pyrazol-1-yl) succinate | 950-225-1 | - |
Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Reaction mass of 2-(3,4-dimethyl-1H-pyrazol-1-yl)succinic acid and 2-(4,5-dimethyl-1H-pyrazol-1-yl)succinic acid (EC number 940-877-5, CAS number 2241455-89-8) Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with Reaction mass of 2-(3,4-dimethyl-1H-pyrazol-1-yl)succinic acid and 2-(4,5-dimethyl-1H-pyrazol-1-yl)succinic acid (EC number 940-877-5, CAS number 2241455-89-8) |
17/12/2019 17/12/2019 |
31/01/2020 31/01/2020 |
Details | |
Saccharomyces cerevisiae cell wall, extracted | 949-711-6 | - |
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Saccharomyces cerevisiae, lysate (EC 305-230-8) Sub-chronic toxicity (90-day): oral || Note: testing proposed with Saccharomyces cerevisiae, lysate (EC 305-230-8) |
25/11/2021 25/11/2021 |
10/01/2022 10/01/2022 |
Details | |
Rectified Hydrocarbons by-products from synthetic process of Turpentine and acid, alcohols fraction | 949-141-8 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
21/01/2021 21/01/2021 |
08/03/2021 08/03/2021 |
Details | |
Hydrocarbons, C16-C18, isoalkanes,<2% aromatics | 948-766-3 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 28/02/2019 | 15/04/2019 | Details | |
pentasodium 4-amino-3-[{4-[(2,4-disulfonatophenyl)diazenyl]-3-methylphenyl}diazenyl]-5-hydroxy-6-[(4-nitro-2-sulfonatophenyl)diazenyl]naphthalene-1,7-disulfonate | 948-569-2 | - | Genetic toxicity in vivo | 01/04/2022 | 16/05/2022 | Details | |
Fatty acids, C14-C18 and C18 unsaturated, amides with 2,2’-iminodiethanol | 948-052-1 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 21/01/2021 | 08/03/2021 | Details | |
Reaction mass of N,N,N',N'-tetrabutylmethylenediamine and dibutylamine | 948-040-6 | - | Genetic toxicity in vivo || Note: Link to registration dossier not given as the dossier not yet disseminated. || Note: Testing proposal is based on concern identified by the registrant. | 24/01/2019 | 11/03/2019 | Details | |
Terpenic base | 947-968-9 | - | Genetic toxicity in vivo | 18/03/2021 | 03/05/2021 | Details | |
2-propenoic acid, butyl ester, reaction products with butadiene and sulfur | 947-895-2 | - |
Bioaccumulation aquatic / sediment Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
15/01/2024 15/01/2024 15/01/2024 15/01/2024 |
29/02/2024 29/02/2024 29/02/2024 29/02/2024 |
Details | |
C18 unsaturated fatty acids, reaction products with 1-aminopropan-2-ol, maleic anhydride and sodium bisulfite | 947-655-7 | - | Long-term toxicity to fish||Note: testing proposed with disodium 4-[1-methyl-2-[(1-oxooctadec-9-enyl)amino]ethyl] 2-sulphonatosuccinate (EC no. 267-199-6) | 15/01/2024 | 29/02/2024 | Details | |
Phosphoric acid, C11-14 (C13-rich)-isoalkyl mono- and di-esters, partially salted with 1-Propanamine, 3-(tridecyloxy)-, branched | 947-480-6 | - | Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposal is based on concern identified by the registrant | 19/10/2020 | 03/12/2020 | Details | |
Reaction products of diazotised 3-amino-2-hydroxy-5-nitrobenzenesulphonic acid, coupled with 1,3-diaminobenzene and diazotised sodium 4-aminobenzenesulfonate, metallized with Basic Chromium (III) Sulphate, sodium salts | 947-395-4 | - | Genetic toxicity in vivo | 18/03/2021 | 03/05/2021 | Details | |
Fatty acids, C12-18 (even numbered)-methyl esters, sulfonated, sodium salts | 947-394-9 | - |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
19/10/2020 19/10/2020 19/10/2020 |
03/12/2020 03/12/2020 03/12/2020 |
Details | |
Sodium salts of [hexane-1,6-diylbis[nitrilobis(methylene)]]tetrakisphosphonic acid (4-7 Na:1) | 947-369-2 | - |
Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Potassium salts of {hexane-1,6-iylbis[nitrilobis(methylene)]}tetrakisphosphonic acid (4-7:1); EC 701-184-1
|| Note: Testing proposal is based on concern identified by the registrant. Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with Potassium salts of {hexane-1,6-iylbis[nitrilobis(methylene)]}tetrakisphosphonic acid (4-7:1); EC 701-184-1
|| Note: Testing proposal is based on concern identified by the registrant. |
27/01/2020 27/01/2020 |
12/03/2020 12/03/2020 |
Details | |
Condensation products of phenol and salicylaldehyde | 947-320-5 | - | Genetic toxicity in vivo | 20/05/2021 | 05/07/2021 | Details | |
Reaction mass of disodium (sulphonatothio)acetate and sodium chloride | 947-115-0 | - | Genetic toxicity in vivo | 17/06/2020 | 03/08/2020 | Details | |
Reaction products of diazotised Sodium Picramate coupled with Resorcinol, subsequently coupled with diazotised 4'-Amino-4-Nitrodiphenylamin-2-Sulfonic Acid, at the end metallized with Iron (II) sulphate heptahydrate, sodium salts | 946-788-8 | - | Genetic toxicity in vivo | 18/03/2021 | 03/05/2021 | Details | |
Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C11-17 and C17 unsatd. alkyl) derivs. and sodium hydroxide and 2-propenoic acid | 946-533-0 | - | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid (EC 931-291-0) | 23/04/2018 | 07/06/2018 | Details | |
Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C11-17 and C17 unsatd. alkyl) derivs. and sodium hydroxide and 2-propenoic acid | 946-533-0 | - | Sub-chronic toxicity (90-day): oral || Note: testing proposed with β-Alanine, N-(2-aminoethyl)-N-(2-hydroxyethyl)-, N-coco acyl derivs., monosodium salts (EC 298-632-7) | 16/12/2020 | 01/02/2021 | Details | |
Reaction mass of 6-Chloro-2-{4[ethyl(2-hydroxyethyl)amino]phenyl}-1-methylbenzo[cd]indolium hydroxide and 6-chloro-2-[4-[ethyl(2-hydroxyethyl)amino]phenyl]-1-methylbenz[cd]indolium acetate | 946-378-9 | - | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant | 16/12/2020 | 01/02/2021 | Details | |
Hydrocarbons, C9-C10, aromatics, >1% naphthalene | 946-365-8 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
21/01/2021 21/01/2021 21/01/2021 |
08/03/2021 08/03/2021 08/03/2021 |
Details | |
Essential oil of Spearmint obtained from the aerial part of Mentha spicata and/or Mentha cardiaca (Lamiaceae) obtained by distillation | 946-253-9 | - | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant | 19/10/2020 | 03/12/2020 | Details | |
Reaction mass of 3,5,6,6-tetramethyl-4-methyleneheptan-2-one and (E)-3,4,5,6,6-pentamethylhept-3-en-2-one | 946-245-5 | - | Reproductive toxicity (pre-natal developmental toxicity) | 06/06/2023 | 21/07/2023 | Details | |
1,4-Benzenedicarboxylic acid, mixed Bu and 2-ethylhexyl diesters | 946-149-3 | 1571954-81-8 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
21/05/2018 21/05/2018 |
05/07/2018 05/07/2018 |
Details | |
Reaction mass of trisodium [μ-[4-[[3,3'-dihydroxy-4'-[(2-hydroxy-6-sulpho-1-naphthyl)azo][1,1'-biphenyl]-4-yl]azo]-3-hydroxynaphthalene-2,7-disulphonato(7-)]]dicuprate(3-) and triammonium [μ-[4-[[3,3'-dihydroxy-4'-[(2-hydroxy-6-sulpho-1-naphthyl)azo][1,1'-biphenyl]-4-yl]azo]-3-hydroxynaphthalene-2,7-disulphonato(7-)]]dicuprate(3-) | 945-577-8 | - | Sub-chronic toxicity (90-day): oral | 01/07/2021 | 16/08/2021 | Details | |
Alkanoic acid and polyoxomolybdate borate alkanoate clusters | 944-813-7 | - | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant | 24/08/2020 | 08/10/2020 | Details | |
Reaction mass of Disodium dihydroxy[3-(hydroxy-kO)-4-{[5-(hydroxy-kO)-3-methyl-1-phenyl-1Hpyrazol-4-yl]diazenyl-kN1}naphthalene-1-sulfonato(3-)]chromate(2-) and sodium [4-[(4,5-dihydro-3-methyl-5-oxo-1-phenyl-1H-pyrazol-4-yl)azo]-3-hydroxynaphthalene-1-sulphonato(3-)]hydroxychromate(1-) | 944-272-7 | - | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant | 19/10/2020 | 03/12/2020 | Details | |
[No public or meaningful name is available] | 944-258-0 | 1850357-57-1 | Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Wax, rice bran, oxidized (Polar modified Rice Bran Wax) | 03/05/2023 | 19/06/2023 | Details | |
Reaction mass of N-butylphthalimide and N-sec-butylphthalimide and N-propylphthalimide | 943-947-3 | - | Genetic toxicity in vivo | 19/10/2020 | 03/12/2020 | Details | |
A dried sludge product resulting from the treatment process of domestic wastewater. The exact processes followed for the production of the dried sludge are: Preliminary and secondary treatment of the wastewater stream, thickening, dehydration and drying of the excess sludge. | 943-834-9 | - |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
03/04/2023 03/04/2023 03/04/2023 |
22/05/2023 22/05/2023 22/05/2023 |
Details | |
Reaction mass of C18 (unsatd.) fatty acid amides/esters of diethanolamine, C16-18 (even-numbered) fatty amine (..) | 943-172-0 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
17/05/2016 17/05/2016 17/05/2016 |
01/07/2016 01/07/2016 01/07/2016 |
Details | |
Reaction mass of trientine and trientine, mono- and di-propoxylated | 942-835-1 | - | Genetic toxicity in vivo||Note: testing proposed with [Amines, polyethylenepoly-, triethylenetetramine fraction] (EC no. 292-588-2) | 03/10/2023 | 17/11/2023 | Details | |
Fatty acids, C12-14, α-sulfo, disodium salts | 942-523-5 | - |
Long-term toxicity to fish (OECD 212 – Registrant’s preference) Reproductive toxicity (pre-natal developmental toxicity) on rodents Sub-chronic toxicity (90-day): oral on rodents |
25/06/2019 25/06/2019 25/06/2019 |
09/08/2019 09/08/2019 09/08/2019 |
Details | |
Fatty acids, C12-14, α-sulfo, disodium salts | 942-523-5 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
02/11/2018 02/11/2018 |
17/12/2018 17/12/2018 |
Details | |
plastic, waste, pyrolized, fractionation bottoms (raw diesel) | 942-177-5 | - | Genetic toxicity in vivo | 10/05/2022 | 27/06/2022 | Details | |
N-Phenyl-diethanolamine, reaction products with formaldehyde | 942-131-4 | - | Genetic toxicity in vivo | 26/08/2021 | 11/10/2021 | Details | |
N-Phenyl-diethanolamine, reaction products with formaldehyde | 942-131-4 | - | Reproductive toxicity (pre-natal developmental toxicity) | 21/10/2021 | 07/12/2021 | Details | |
Sophorolipids: fermentation products of glucose and fatty acids, C18 (unsaturated), glycerol esters with yeast Candida Bombicola, partially hydrolysed | 941-809-7 | - | Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposal is based on concern identified by the registrant. | 24/07/2019 | 09/09/2019 | Details | |
Petroleum diesel/gas oil fraction, co-processed with renewable hydrocarbons derived from thermally cracked plastics | 941-803-4 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with Gas oils (petroleum), light vacuum (EC no. 265-059-9) Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Gas oils (petroleum), light vacuum (EC no. 265-059-9)
||Note: testing proposed with Fuels, diesel (EC no. 269-822-7)
||Note: testing proposed with Fuel oil, no. 4 (EC no. 270-673-5)
||Note: testing proposed with Distillates (petroleum), light hydrocracked (EC no. 265-078-2) Sub-chronic toxicity (90-day): oral||Note: testing proposed with Gas oils (petroleum), light vacuum (EC no. 265-059-9) |
26/10/2022 26/10/2022 26/10/2022 |
12/12/2022 12/12/2022 12/12/2022 |
Details | |
2-Propyn-1-ol, reaction product with 1-2.5 moles of oxirane | 941-793-1 | - | Reproductive toxicity (pre-natal developmental toxicity) | 26/04/2019 | 10/06/2019 | Details | |
2-Propyn-1-ol, reaction product with 1-2.5 moles of oxirane | 941-793-1 | - | Sub-chronic toxicity (90-day): oral || Note: testing proposed with 2-Propyn-1-ol, compd. with methyloxirane (EC 609-530-2, CAS 38172-91-7) | 17/04/2015 | 04/06/2015 | Details | |
1,3-Butanediol, reaction products with 1,1'-methylenebis[4-isocyanatobenzene], propylene glycol and tripropylene glycol | 941-496-7 | 1689576-89-3 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC 202-966-0) | 01/04/2022 | 16/05/2022 | Details | |
Fatty acids, tall-oil, di- and triesters with trimethylolpropane | 941-376-4 | - |
Long-term toxicity to aquatic invertebrates Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates. Testing proposed with EC No 931-531-4. |
31/05/2016 31/05/2016 31/05/2016 |
15/07/2016 15/07/2016 15/07/2016 |
Details | |
3-methyldecane; benzene; cyclooctane; nonane | 941-364-9 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 05/07/2018 | 20/08/2018 | Details | |
Reaction mass of 2,2'-{methylenebis[(2,6-dimethyl-4,1-phenylene)oxymethylene]}dioxirane and 1,3-bis{4-[3,5-dimethyl-4-(oxiran-2-ylmethoxy)benzyl]-2,6-dimethylphenoxy}propan-2-ol and 3,3'-{methylenebis[(2,6-dimethyl-4,1-phenylene)oxy]}bis(1-{4-[3,5-dimethyl-4-(oxiran-2-ylmethoxy)benzyl]-2,6-dimethylphenoxy}propan-2-ol) | 941-357-0 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 21/10/2019 | 05/12/2019 | Details | |
Reaction mass of 2-[[4-[[3,5-dimethyl-4-(oxiran-2-ylmethoxy)phenyl]methyl]-2,6-dimethyl-phenoxy]methyl]oxirane and 1,3-bis[4-[[3,5-dimethyl-4-(oxiran-2-ylmethoxy)phenyl]methyl]-2,6-dimethyl-phenoxy]propan-2-ol and 1-[4-[[3,5-dimethyl-4-(oxiran-2-ylmethoxy)phenyl]methyl]-2,6-dimethyl-phenoxy]-3-[4-[[4-[3-[4-[[3,5-dimethyl-4-(oxiran-2-ylmethoxy)phenyl]methyl]-2,6-dimethyl-phenoxy]-2-hydroxy-propoxy]-3,5-dimethyl-phenyl]methyl]-2,6-dimethyl-phenoxy]propan-2-ol | 941-357-0 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
08/02/2017 08/02/2017 |
27/03/2017 27/03/2017 |
Details | |
Hexanoic acid, 3,5,5-trimethyl-, 2,2,6,6-tetramethyl-1-[2-[(3,5,5-trimethyl-1-oxohexyl)oxy]ethyl]-4-piperidinyl ester | 941-267-1 | 1445870-18-7 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
31/01/2023 31/01/2023 31/01/2023 |
17/03/2023 17/03/2023 17/03/2023 |
Details | |
Cashew (Anacardium occidentale) Nutshell Extract, Decarboxylated | 941-216-3 | - |
Bioaccumulation aquatic / sediment || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Testing proposal is based on concern identified by the registrant. Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Testing proposal is based on concern identified by the registrant. Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Testing proposal is based on concern identified by the registrant. Sub-chronic toxicity (90-day): oral || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Testing proposal is based on concern identified by the registrant. |
15/07/2014 15/07/2014 15/07/2014 15/07/2014 |
29/08/2014 29/08/2014 29/08/2014 29/08/2014 |
Details | |
Cashew (Anacardium occidentale) Nutshell Extract, Decarboxylated, Distillation Residue | 941-212-1 | - |
Bioaccumulation aquatic / sediment || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Testing proposal is based on concern identified by the registrant. Sub-chronic toxicity (90-day): oral || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). |
15/07/2014 15/07/2014 15/07/2014 15/07/2014 |
29/08/2014 29/08/2014 29/08/2014 29/08/2014 |
Details | |
3-{[3-(C10-16-oxy)propyl]amino}propan-1-aminium acetate | 941-152-6 | - | Sub-chronic toxicity (90-day): oral||Note: testing proposed with 1,3-propanediamine, N-[3-((C11-14, C13-rich)oxy)propyl]-branched acetate (EC: 931-295-2) | 15/07/2022 | 29/08/2022 | Details | |
Reaction mass of 2-(3,4-dimethyl-1H-pyrazol-1-yl)succinic acid and 2-(4,5-dimethyl-1H-pyrazol-1-yl)succinic acid | 940-877-5 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
29/03/2019 29/03/2019 |
13/05/2019 13/05/2019 |
Details | |
Bis(2-chloroethoxy)methane 1,15-dichloro-3,5,8,11,13-penta-oxa pentadecane 1-(2-chloroethoxy)-2-(2-chloroethoxymethoxy)ethane | 940-783-4 | - |
Genetic toxicity in vivo Long-term toxicity to fish Reproductive toxicity (two-generation reproductive toxicity) // Note: test to be performed with analogues substance 1-chloro-2-[(2-chloroethoxy)methoxy]ethane (EC 203-920-2 ) |
02/06/2014 02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 17/07/2014 |
Details | |
reaction mass of bis(2,3-epoxypropyl) terephthalate and tris(oxiranylmethyl) benzene-1,2,4-tricarboxylate | 940-592-6 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) || Note: Testing proposal is based on concern identified by the registrant Sub-chronic toxicity (90-day): oral |
16/02/2015 16/02/2015 16/02/2015 |
02/04/2015 02/04/2015 02/04/2015 |
Details | |
Fatty acids, tall oil and rosin reacted with maleic anhydride | 940-281-5 | - |
Reproductive toxicity (pre-natal developmental toxicity) //Note:testing to be done with rosin maleated (CAS 8050-28-0) Sub-chronic toxicity (90-day): oral. //Note:testing to be done with rosin maleated (CAS 8050-28-0) |
18/02/2014 18/02/2014 |
04/04/2014 04/04/2014 |
Details | |
Bis[C5-(branched)-alkyl]l benzene-1,4-dicarboxylate | 940-272-6 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity Sub-chronic toxicity (90-day): oral |
01/09/2017 01/09/2017 01/09/2017 |
16/10/2017 16/10/2017 16/10/2017 |
Details | |
Nonanoic acid (branched), 2-oxiranylmethyl ester | 940-029-4 | - |
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 2,3-epoxypropyl neodecanoate (EC No. 247-979-2) Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with 2,3-epoxypropyl neodecanoate (EC No. 247-979-2) Sub-chronic toxicity (90-day): oral || Note: testing proposed with 2,3-epoxypropyl neodecanoate (EC No. 247-979-2) |
20/09/2013 20/09/2013 20/09/2013 |
04/11/2013 04/11/2013 04/11/2013 |
Details | |
Reaction Mass of Cis-4-(isopropyl) cyclohexanemethanol and Trans-4-(isopropyl) cyclohexanemethanol | 939-719-8 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 |
Details | |
calcium bis(di C8-C10, branched, C9 rich, alkylnaphthalenesulphonate) | 939-717-7 | - | Sub-chronic toxicity (90-day): oral | 02/06/2014 | 17/07/2014 | Details | |
Reaction mass of ethoxylated (= 3 moles) bisphenol A dimethacrylate and (1-methylethylidene)bis(4,1-phenyleneoxy-2,1-ethanediyl) bismethacrylate | 939-702-5 | - | Long-term toxicity to fish | 25/11/2019 | 09/01/2020 | Details | |
Reaction mass of ethoxylated (≥ 3 moles) bisphenol A dimethacrylate and (1-methylethylidene)bis(4,1-phenyleneoxy-2,1-ethanediyl) bismethacrylate | 939-702-5 | - |
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Ethoxylated bisphenol A diacrylate Sub-chronic toxicity (90-day): oral || Note: testing proposed with Ethoxylated bisphenol A diacrylate |
12/12/2014 12/12/2014 |
26/01/2015 26/01/2015 |
Details | |
N,N-bis(2-ethylhexyl)-5-methyl-1H-benzotriazole-1-methylamine, N,N-bis(2-ethylhexyl)-4-methyl-1H-benzotriazole-1-methylamine, 2H-Benzotriazole-2-methanamine, N,N-bis(2-ethylhexyl)-4-methyl-, 2H-Benzotriazole-2-methanamine, N,N-bis(2-ethylhexyl)-5-methyl-, 1H-Benzotriazole-1-methanamine, N,N-bis(2-ethylhexyl)-6-methyl-(Mixture) | 939-700-4 | - | Sub-chronic toxicity (90-day): oral | 21/10/2019 | 05/12/2019 | Details | |
Butanoic acid, 4-amino-4-oxo-2(or 3)-sulfo-,N-(C16-C18 (even numbered), C18 unsaturated alkyl)), disodium salts | 939-691-7 | - | Reproductive toxicity (pre-natal developmental toxicity) | 17/09/2019 | 01/11/2019 | Details | |
N,N-dimethyl-alkyl-1-amines, reaction products with alkali hydroxide and chloroacetic acid | 939-682-8 | - |
Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study) |
10/05/2022 10/05/2022 |
27/06/2022 27/06/2022 |
Details | |
Reaction mass of 1-(C12-18-(even numbered))-alkyl-tetrahydropyrimidin-2(1H)-imine acetate salt and 1-(3-((C12-18-(even numbered))-alkyl-amino)propyl)guanidine acetate salt and 1-(C12-18-(even numbered))-alkyl-1-(3-guanidinopropyl)guanidine acetate salt | 939-650-3 | - | Sub-chronic toxicity (90-day): oral | 10/05/2022 | 27/06/2022 | Details | |
Reaction mass of 1-(C12-18-(even numbered))-alkyl-tetrahydropyrimidin-2(1H)-imine acetate salt and 1-(3-((C12-18-(even numbered))-alkyl-amino)propyl)guanidine acetate salt and 1-(C12-18-(even numbered))-alkyl-1-(3-guanidinopropyl)guanidine acetate salt | 939-650-3 | - | Reproductive toxicity (pre-natal developmental toxicity) | 14/08/2014 | 28/09/2014 | Details | |
Distilled tall oil, magnesium salts | 939-629-9 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
30/11/2015 30/11/2015 |
14/01/2016 14/01/2016 |
Details | |
Hydrocarbons, C14-C17, isoalkanes, cyclics, <2% aromatics | 939-601-6 | - | Reproductive toxicity (two-generation reproductive toxicity) // Note: testing proposed with Icosane (C20 normal alkanes); Hydrocarbons, C14-C19, isoalkane, cyclics, < 2%; Hydrocarbon, C16-C20, normal, isoalkane, cyclics, 2-30% aromatics | 02/06/2014 | 17/07/2014 | Details | |
Reaction mass of potassium ethyl octylphosphonate and diethyl octylphosphonate | 939-595-5 | - | Reproductive toxicity (pre-natal developmental toxicity) | 17/04/2015 | 04/06/2015 | Details | |
Reaction Products of alcohols, C14-18, C18 unsat., esterified with phosphorus pentoxide and salted with amines, C12-14,-tert-alkyl | 939-591-3 | - | Reproductive toxicity (pre-natal developmental toxicity) | 15/04/2014 | 30/05/2014 | Details | |
3-C12-18-(even numbered)-alkylamido-N,N-dimethylpropan-1-amino oxide | 939-581-9 | - | Reproductive toxicity (pre-natal developmental toxicity) | 26/03/2018 | 11/05/2018 | Details | |
Reaction mass of Ammonium bisethanedioato bisaquo niobate(V) (anhydrous form) and Ammonium hydrogen ethanedioate ethanedioic acid (anhydrous form | 939-559-9 | - | Reproductive toxicity (pre-natal developmental toxicity) | 01/09/2017 | 16/10/2017 | Details | |
Fatty acid chlorides, C18 unsatd., reaction products with sodium N-methyltaurinate | 939-538-4 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
04/04/2014 04/04/2014 |
19/05/2014 19/05/2014 |
Details | |
Reaction mass of [[(2-hydroxyethyl)imino]dimethylene]bisphosphonic acid, sodium salt and 4-(Phosphonomethyl)-2-hydroxy-2-oxo-1,4,2-oxazaphosphorinane, sodium salt | 939-513-8 | - |
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed either the registered substance or a read-across substance, which would be the acid form of the registered substance Sub-chronic toxicity (90-day): oral Note: testing proposed either the registered substance or a read-across substance, which would be the acid form of the registered substance |
25/06/2015 25/06/2015 |
10/08/2015 10/08/2015 |
Details | |
Reaction product of 2,4-Dinitrotoluene and 2,6-Dinitrotoluene and hydrogen | 939-489-9 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): oral |
02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 |
Details | |
Reaction product of 2,4-Dinitrotoluene and 2,6-Dinitrotoluene and hydrogen | 939-489-9 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
18/02/2021 18/02/2021 |
05/04/2021 05/04/2021 |
Details | |
3-((C9-11-iso,C10-rich)alkyloxy)propan-1-amine | 939-485-7 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 |
Details | |
Reaction products of tryglycerides, C8-C18 (even numbered) and C18-unsaturated, glycerine and ethylene oxide | 939-459-5 | - | Sub-chronic toxicity (90-day): oral | 30/11/2015 | 14/01/2016 | Details | |
1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C12-18(even numbered) acyl) derivs., hydroxides, inner salts | 939-457-4 | - |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/09/2014 18/09/2014 18/09/2014 |
03/11/2014 03/11/2014 03/11/2014 |
Details | |
1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C8-18(even numbered) acyl) derivs., hydroxides, inner salts | 939-455-3 | - |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): oral |
18/09/2014 18/09/2014 18/09/2014 |
03/11/2014 03/11/2014 03/11/2014 |
Details | |
3-((C9-11-iso,C10-rich)alkyloxy)propan-1-amine acetate (1:1) | 939-448-5 | - |
Reproductive toxicity (pre-natal developmental toxicity)
|| Note: Testing proposed with 1-Propanamine, 3-((C9-11-iso-,C10-rich)alkyloxy)- Sub-chronic toxicity (90-day): oral
|| Note: Testing proposed with 1-Propanamine, 3-((C9-11-iso-,C10-rich)alkyloxy)- |
02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 |
Details | |
Reaction mass of (2S-cis)-tetrahydro-4-methyl-2-(2-methyl-1-propenyl)-2H-pyran and Tetrahydro-4-methyl-2-(2-methylpropen-1-yl)pyran (2R,4R) and Tetrahydro-4-methyl-2-(2-methylpropen-1-yl)pyran (2S,4S) and (2R-cis)-tetrahydro-4-methyl-2-(2-methyl-1-propenyl)-2H-pyran | 939-429-1 | 16409-43-1 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
30/11/2015 30/11/2015 |
14/01/2016 14/01/2016 |
Details | |
Fatty acids, tall-oil, reaction products with acrylic acid | 939-424-4 | - | Long-term toxicity to fish | 04/04/2014 | 19/05/2014 | Details | |
2-Oxetanone, 3-C12-16-alkyl-4-C13-17-alkylidene derivs., (4E)- | 939-401-9 | 1469983-41-2 | Long-term toxicity to fish ||Note: testing proposed with 2-Oxetanone, 3-C14-16-alkyl 4-C15-17-alkylidene derivs (EC no. 308-760-8) | 15/07/2022 | 29/08/2022 | Details | |
Reaction products of diazotised 4,4-diaminodiphenylamine-2-sulfonic acid, subsequently coupled with 6-amino-4-hydroxynaphthalene-2-sulfonic acid, further diazotised and coupled with metaphenylendiamine, sodium salts | 939-382-7 | - | Genetic toxicity in vivo | 25/11/2021 | 10/01/2022 | Details | |
Nickel, 5,5'-azobis-2,4,6(1H,3H,5H)-pyrimidinetrione complexes and melamine | 939-379-0 | - | Reproductive toxicity (pre-natal developmental toxicity) | 04/04/2014 | 19/05/2014 | Details | |
Reaction product of naphthalene, propan-2-ol, sulfonated and neutralized by caustic soda | 939-368-0 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): inhalation |
17/06/2014 17/06/2014 |
01/08/2014 01/08/2014 |
Details | |
Reaction mass of sodium hydrogen N-(1-oxooctadecyl)-L-glutamate and stearic acid | 939-201-1 | - | Reproductive toxicity (pre-natal developmental toxicity) | 25/06/2015 | 10/08/2015 | Details | |
Reaction mass of 4-tert-butylphenol and 1,3- phenylenedimethanamine and 2-({[3-(aminomethyl) benzyl]amino}methyl)-4-tert-butylphenol | 939-071-6 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
02/07/2013 02/07/2013 |
16/08/2013 16/08/2013 |
Details | |
Reaction mass of 3-isopropyl-6-methylenecyclohexene and (4R)-1-methyl-4-(prop-1-en-2-yl)cyclohexene and (4S)-1-methyl-4-(prop-1-en-2-yl)cyclohexene | 939-009-8 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
22/09/2022 22/09/2022 |
07/11/2022 07/11/2022 |
Details | |
Reaction mass of 3-isopropyl-6-methylenecyclohexene and (4R)-1-methyl-4-(prop-1-en-2-yl)cyclohexene and (4S)-1-methyl-4-(prop-1-en-2-yl)cyclohexene | 939-009-8 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
01/09/2017 01/09/2017 |
16/10/2017 16/10/2017 |
Details | |
Reaction mass of 3-isopropyl-6-methylenecyclohexene and (4R)-1-methyl-4-(prop-1-en-2-yl)cyclohexene and (4S)-1-methyl-4-(prop-1-en-2-yl)cyclohexene | 939-009-8 | - | Sub-chronic toxicity (90-day): oral | 21/12/2021 | 04/02/2022 | Details | |
Reaction products of n-octanol and acrylic acid, first distillation pitch | 938-925-5 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/03/2021 18/03/2021 |
03/05/2021 03/05/2021 |
Details | |
Reaction products of n-octanol and acrylic acid, first distillation pitch | 938-925-5 | - | Long-term toxicity to fish | 15/01/2024 | 29/02/2024 | Details | |
Middle distillate from refinery proces cofeeding vegetable oil | 938-793-9 | - | Reproductive toxicity (two-generation reproductive toxicity) | 02/09/2013 | 18/10/2013 | Details | |
Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C11-C13 odd-numbered alkyl) derivs. and sodium hydroxide and chloroacetic acid | 938-645-3 | - |
Long-term toxicity to fish
Note: testing proposed with [Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C11 alkyl) derivs. and sodium hydroxide and chloroacetic acid] (EC 271-794-6) Reproductive toxicity (pre-natal developmental toxicity)
Note: testing proposed with [Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid] (EC 931-291-0) Sub-chronic toxicity (90-day): oral
Note: testing proposed with [Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid] (EC 931-291-0) |
16/03/2015 16/03/2015 16/03/2015 |
30/04/2015 30/04/2015 30/04/2015 |
Details | |
Reaction mass of 2-ethyl-2-(methoxymethyl)-propane-1,3-diol and 2-ethylpropane-1,3-diol | 938-572-7 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
06/09/2018 06/09/2018 |
22/10/2018 22/10/2018 |
Details | |
Reaction mass of 2-ethyl-2-(methoxymethyl)-propane-1,3-diol and 2-ethylpropane-1,3-diol | 938-572-7 | - | Long-term toxicity to fish | 22/09/2022 | 07/11/2022 | Details | |
Ashes (residues), nonhazardous municipal solid waste | 937-417-0 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
17/08/2012 17/08/2012 |
01/10/2012 01/10/2012 |
Details | |
Ashes (residues), nonhazardous municipal solid waste | 937-417-0 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
25/05/2020 25/05/2020 |
09/07/2020 09/07/2020 |
Details | |
Hydrocarbons, C17-C19, n-alkanes, <2% aromatics | 937-158-3 | - | Reproductive toxicity (two-generation reproductive toxicity) | 25/06/2012 | 09/08/2012 | Details | |
Reaction mass of dibutyl adipate and dibutyl glutarate | 936-196-8 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with Reaction mass of dimethyl adipate, dimethyl glutarate and dimethyl succinate (EC 906-170-0) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Reaction mass of dimethyl adipate, dimethyl glutarate and dimethyl succinate (EC 906-170-0) |
16/12/2020 16/12/2020 |
01/02/2021 01/02/2021 |
Details | |
Decene, hydroformylation products, high boiling | 935-454-7 | - |
Reproductive toxicity (pre-natal developmental toxicity) // Note: testing proposed with Alkenes, C11-12, hydroformylation products, distn. residues (CAS: 90622-27-8) Sub-chronic toxicity (90-day): oral // Note: testing proposed with Alkenes, C11-12, hydroformylation products, distn. residues (CAS: 90622-27-8) |
02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 |
Details | |
C26-28 (even numbered) α-alkenes | 934-268-3 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
18/06/2012 18/06/2012 18/06/2012 |
02/08/2012 02/08/2012 02/08/2012 |
Details | |
Reaction mass of N-[2-(2-oxoimidazolidin-1-yl)ethyl]methacrylamide and methacrylic acid | 934-058-1 | - |
Genetic toxicity in vivo Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/05/2014 16/05/2014 16/05/2014 16/05/2014 |
30/06/2014 30/06/2014 30/06/2014 30/06/2014 |
Details | |
Slags, steelmaking, elec. furnace (stainless/high alloy steel production) | 932-476-9 | - | Sub-chronic toxicity (90 day): inhalation | 06/03/2012 | 20/04/2012 | Details | |
Alkenes, C11-12, hydroformylation products, low boiling | 932-235-8 | - | Reproductive toxicity (two-generation reproductive toxicity) | 16/06/2011 | 01/08/2011 | Details | |
Reaction mass of Amides, rape-oil, N-(hydroxyethyl), ethoxylated and Glycerol, ethoxylated | 932-164-2 | - |
Long-term toxicity to fish Sub-chronic toxicity (90-day): oral |
29/07/2011 29/07/2011 |
12/09/2011 12/09/2011 |
Details | |
Calcium dihydroxide precipitated with carbon dioxide during sugar juice purification | 932-124-4 | - | Sub-chronic toxicity (90 day): inhalation | 01/07/2011 | 15/08/2011 | Details | |
N-[3-(dimethylamino)propyl] C 12-C18 alkylamide | 932-121-8 | 1147459-12-8 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/09/2014 18/09/2014 |
03/11/2014 03/11/2014 |
Details | |
Reaction mass of p-mentha-1,4-diene and p-mentha-1,3-diene and dipentene and p-mentha-1(7),2-diene and p-mentha-1,4(8)-diene | 931-893-3 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
15/09/2011 15/09/2011 |
31/10/2011 31/10/2011 |
Details | |
Reaction mass of Alkenes C20-24 and Alkenes C24-28 | 931-746-3 | 93924-10-8 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
03/11/2011 03/11/2011 16/07/2012 |
19/12/2011 19/12/2011 30/08/2012 |
Details | |
Imidazolium compounds, 2-C17-unsatd.-alkyl-1-(2-C18-unsatd. amidoethyl)-4,5-dihydro-N-methyl, Me sulfates | 931-745-8 | - | Sub-chronic toxicity (90-day): oral | 01/07/2011 | 15/08/2011 | Details | |
Amides, C16-C18 (even numbered) | 931-695-7 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/08/2011 16/08/2011 |
30/09/2011 30/09/2011 |
Details | |
Reaction mass of bisisopropyl peroxydicarbonate and bis-sec-butyl peroxydicarbonate and isopropyl-sec-butylperoxydicarbonate | 931-536-1 | - | Genetic toxicity in vivo || Note: testing proposed with bisisopropyl peroxydicarbonate EC 203-317-4, CAS 105-64-6 (is a constituent of the multi-constituent registered substance) || Note: Testing proposal is based on concern identified by the registrant | 24/08/2020 | 08/10/2020 | Details | |
Alkenes, C11-12 | 931-515-7 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
03/11/2011 03/11/2011 25/06/2012 |
19/12/2011 19/12/2011 09/08/2012 |
Details | |
Alkenes, C21-32 linear and branched | 931-505-2 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
15/09/2011 15/09/2011 25/06/2012 |
31/10/2011 31/10/2011 09/08/2012 |
Details | |
Alkenes C20+ | 931-467-7 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
15/09/2011 15/09/2011 |
31/10/2011 31/10/2011 |
Details | |
Magnesium, bis(2-hydroxybenzoato-O1,O2)-, ar,ar'-di-C14-18alkyl derivs | 931-371-5 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 23/04/2018 | 07/06/2018 | Details | |
Activated Carbon - High Density Skeleton | 931-328-0 | - | Sub-chronic toxicity (90 day): inhalation | 16/06/2011 | 01/08/2011 | Details | |
3-C12-14-(even numbered)-alkylamido-N,N-dimethylpropan-1-amino oxide | 931-324-9 | - | Sub-chronic toxicity (90-day): oral | 02/09/2011 | 17/10/2011 | Details | |
Amides, C16-C18 (even) , N,N'-ethylenebis | 931-299-4 | 68390-94-3 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
01/03/2023 01/03/2023 |
17/04/2023 17/04/2023 |
Details | |
Amides, C16-C18 (even) , N,N'-ethylenebis | 931-299-4 | - | Sub-chronic toxicity (90-day): oral | 16/08/2011 | 30/09/2011 | Details | |
1,3-Propanediamine, N-[3-((C11-14, C13-rich)oxy)propyl]- branched acetate | 931-295-2 | - | Sub-chronic toxicity (90-day): oral | 25/05/2020 | 09/07/2020 | Details | |
Reaction mass of 1,3-Propanediamine, N-[3-(tridecyloxy)propyl]-, branched and 1,3-Propanediamine, N-[3-(tridecyloxy)propyl]-, branched acetate | 931-295-2 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
15/09/2011 15/09/2011 15/09/2011 |
31/10/2011 31/10/2011 31/10/2011 |
Details | |
Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid | 931-291-0 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
23/03/2020 23/03/2020 |
07/05/2020 07/05/2020 |
Details | |
Benzoic acid, 2-hydroxy-, mono-C14-18-alkyl derivs., calcium salts (2:1) | 931-276-9 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 23/04/2018 | 07/06/2018 | Details | |
Hydrocarbons, C14-C20, n-alkanes, isoalkanes, <2% aromatics | 931-265-9 | - | Reproductive toxicity (two-generation reproductive toxicity) | 25/06/2012 | 09/08/2012 | Details | |
Product of Semi-Dry Absorption method of Flue Gas Desulphurization (SDA Product) | 931-259-6 | - |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) |
02/09/2011 02/09/2011 |
17/10/2011 17/10/2011 |
Details | |
Ashes from fluidized Bed combustion coal fired Power stations with and without co-combustion of secondary fuels (biomass,other fuels - to be verified in view of ecotoxicological and toxicological tests) | 931-257-5 | - | Reproductive toxicity (pre-natal developmental toxicity) | 05/04/2011 | 20/05/2011 | Details | |
Amorphous glass product formed from the melting and fiberisation of dipotassium oxide, oxo(oxoalumanyloxy)alumane and dioxosilane | 931-219-8 | - | Sub-chronic toxicity (90 day): inhalation | 24/05/2013 | 08/07/2013 | Details | |
Fatty acids, C18 unsatd., reaction products with triethanolamine, di-Me sulfate-quaternized | 931-216-1 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
15/03/2011 15/03/2011 |
29/04/2011 29/04/2011 |
Details | |
Reaction products of C18 (unsaturated) fatty acids and dimethyl sulfate and triethanolamine | 931-216-1 | - | Long-term toxicity to fish || Note: testing proposed with Fatty acids, C16-18 (even numbered) and C18 unsatd., reaction products with diethylene triamine, di-Me sulfate quaternized (EC 937-237-2) | 22/04/2021 | 07/06/2021 | Details | |
Fatty acids, C16-18 (even numbered), reaction products with triethanolamine, di-Me sulfate-quaternized | 931-209-3 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
15/03/2011 15/03/2011 |
29/04/2011 29/04/2011 |
Details | |
Fatty acids, C16-18 (even numbered) and C18 unsatd., reaction products with triethanolamine, di-Me sulfate-quaternized | 931-203-0 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
15/03/2011 15/03/2011 |
29/04/2011 29/04/2011 |
Details | |
Hydrocarbons, C11-C12, isoalkanes, cyclics, <2% aromatics | 931-121-5 | - | Reproductive toxicity (two-generation reproductive toxicity) | 25/06/2012 | 09/08/2012 | Details | |
Alkenes, C13-14 | 931-071-4 | - | Sub-chronic toxicity (90-day): oral | 25/06/2012 | 09/08/2012 | Details | |
Shale oils, heavy | 930-690-7 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
17/11/2011 14/03/2016 14/03/2016 |
02/01/2012 28/04/2016 28/04/2016 |
Details | |
Reaction product of Crude sludge and Calcium oxide. Crude sludge is the mixture of by-products of petroleum hydrocarbons refining (especially Total petroleum hydrocarbons, Polycyclic aromatic hydrocarbons, acid-refined heavy petroleum distillates). The Crude sludge is neutralised by calcium oxide in the ratio 80:20. The maturing process proceeds under ambient conditions and takes for at least 3 days. Subsequently, the reaction product is processed mechanically | 930-592-4 | - | Reproductive toxicity (pre-natal developmental toxicity) | 20/09/2013 | 04/11/2013 | Details | |
4'-Ethyl-2,3-difluorbiphenyl-4-boronic acid | 929-209-3 | - | Genetic toxicity in vivo | 16/12/2020 | 01/02/2021 | Details | |
Hydrocarbons, C10-C13, n-alkanes, <2% aromatics | 929-018-5 | - | Reproductive toxicity (two-generation reproductive toxicity) | 25/06/2012 | 09/08/2012 | Details | |
Hydrocarbons, C13-C18, n-alkanes, isoalkanes, cyclics, <2% aromatics | 928-253-0 | - | Reproductive toxicity (two-generation reproductive toxicity) | 25/06/2012 | 09/08/2012 | Details | |
Octadecylamine, reaction products with 4,4'-methylenediphenyl diisocyanate | 928-226-3 | - | Sub-chronic toxicity (90-day): oral | 16/10/2014 | 01/12/2014 | Details | |
Hydrocarbons, C8-C12, n-alkanes, isoalkanes, cyclics, aromatics (2-25%) | 928-136-4 | - | Reproductive toxicity (two-generation reproductive toxicity) | 25/06/2012 | 09/08/2012 | Details | |
Acetalization products between glucose and C16-18(even numbered)- alcohol | 927-870-2 | - | Sub-chronic toxicity (90-day): oral | 15/09/2011 | 31/10/2011 | Details | |
Hydrocarbons, C12-C16, isoalkanes, cyclics, <2% aromatics | 927-676-8 | - | Reproductive toxicity (two-generation reproductive toxicity) | 25/06/2012 | 09/08/2012 | Details | |
Hydrocarbons, C14-C18, n-alkanes, isoalkanes, cyclics, <2% aromatics | 927-632-8 | - | Reproductive toxicity (two-generation reproductive toxicity) | 25/06/2012 | 09/08/2012 | Details | |
Hydrocarbons, C9-C10, n-alkanes, isoalkanes, cyclics, aromatics (2-25%) | 927-344-2 | - | Reproductive toxicity (two-generation reproductive toxicity) | 25/06/2012 | 09/08/2012 | Details | |
Hydrocarbons, C11-C14, isoalkanes, cyclics, <2% aromatics | 927-285-2 | - | Reproductive toxicity (two-generation reproductive toxicity) | 25/06/2012 | 09/08/2012 | Details | |
Hydrocarbons, C9-C10, n-alkanes, isoalkanes, cyclics, <2% aromatics | 927-241-2 | - | Reproductive toxicity (two-generation reproductive toxicity) | 25/06/2012 | 09/08/2012 | Details | |
2,2',6,6'-Tetrabromo-4,4'-isopropylidenediphenol, oligomeric reaction products with Propylene oxide and n-butyl glycidyl ether | 926-564-6 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
21/10/2019 21/10/2019 |
05/12/2019 05/12/2019 |
Details | |
Hydrocarbons, C11-C14, n-alkanes, isoalkanes, cyclics, <2% aromatics | 926-141-6 | - | Reproductive toxicity (two-generation reproductive toxicity) | 25/06/2012 | 09/08/2012 | Details | |
Reaction product of 4,4'-methylenediphenyl diisocyanate (MDI) (101-68-8), Octylamine (111-86-4) and Cyclohexylamine (108-91-8) | 926-119-6 | - | Long-term toxicity to fish || Note: testing proposed with Reaction mass of 4,4'-methylenediphenyl diisocyanate and Amines, soya alkyl (EC 905-837-3) and Reaction product of 4,4'-methylenediphenyl diisocyanate (MDI) (CAS: 101-68-8), Octylamine (111-86-4) and Hexamethylenediamine (124-09-4) (EC no 924-670-7) | 30/09/2021 | 15/11/2021 | Details | |
(Reaction product of 4-[2-(4-hydroxyphenyl)propan-2-yl]phenol, 2-(2-hydroxyethylamino)ethanol and formaldehyde), propoxylated | 926-000-9 | - | Reproductive toxicity (pre-natal developmental toxicity) | 04/04/2014 | 19/05/2014 | Details | |
Hydrocarbons, C9-C11, cyclics, <2% aromatics | 925-894-8 | - | Reproductive toxicity (two-generation reproductive toxicity) | 25/06/2012 | 09/08/2012 | Details | |
Hydrocarbons, C11-C14, n-alkanes, isoalkanes, cyclics, aromatics (2-25%) | 925-653-7 | - | Reproductive toxicity (two-generation reproductive toxicity) | 25/06/2012 | 09/08/2012 | Details | |
1,6-hexanediyl-bis(2-(2-(1-ethylpentyl)-3-oxazolidinyl)ethyl)carbamate | 925-259-5 | 140921-24-0 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/05/2014 16/05/2014 16/05/2014 |
30/06/2014 30/06/2014 30/06/2014 |
Details | |
Hydrocarbons, C11-C14, n-alkanes, <2% aromatics | 924-803-9 | - | Reproductive toxicity (two-generation reproductive toxicity) | 25/06/2012 | 09/08/2012 | Details | |
Reaction product of 4,4'-methylenediphenyl diisocyanate, Octylamine and Hexamethylenediamine | 924-670-7 | - | Long-term toxicity to fish || Note: testing proposed with Reaction mass of 4,4'-methylenediphenyl diisocyanate and Amines, soya alkyl (EC no. 905-837-3) | 16/06/2022 | 01/08/2022 | Details | |
Acetalization products between glucose and C20-22(even numbered)- alcohol | 923-835-0 | - | Sub-chronic toxicity (90-day): oral | 15/09/2011 | 31/10/2011 | Details | |
Shale oils, light | 923-592-0 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) “|| Note: testing proposed with Shale oils, heavy fraction (Registration No 01-2119756217-35-0000)||” Sub-chronic toxicity (90-day): oral “|| Note: testing proposed with Shale oils, heavy fraction (Registration No 01-2119756217-35-0000)||” | 14/03/2016 | 28/04/2016 | Details | |
Shale oils, light | 923-592-0 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
17/11/2011 17/11/2011 17/11/2011 |
02/01/2012 02/01/2012 02/01/2012 |
Details | |
Hydrocarbons, C10-C12, isoalkanes, < 2% aromatics | 923-037-2 | - | Reproductive toxicity (two-generation reproductive toxicity) | 25/06/2012 | 09/08/2012 | Details | |
Hydrocarbons, C10-C13, aromatics, | 922-153-0 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
21/01/2021 21/01/2021 21/01/2021 |
08/03/2021 08/03/2021 08/03/2021 |
Details | |
Hydrocarbons, C7-C9, isoalkanes | 921-728-3 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
21/01/2021 21/01/2021 21/01/2021 |
08/03/2021 08/03/2021 08/03/2021 |
Details | |
Hydrocarbons, C14-C16, n-alkanes, <2% aromatics | 921-535-4 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 02/11/2018 | 17/12/2018 | Details | |
Hydrocarbons, C13-C18, n-alkanes, isoalkanes, cyclics, < 2% aromatics | 921-050-8 | - | Reproductive toxicity (two-generation reproductive toxicity) | 25/06/2012 | 09/08/2012 | Details | |
1-(4-(ACETYLOXY)-3-((ACETYLOXY)METHYL)PHENYL)ETHANONE | 921-042-4 | - | Genetic toxicity in vivo | 25/05/2020 | 09/07/2020 | Details | |
Hydrocarbons, C11-C13, isoalkanes, <2% aromatics | 920-901-0 | - | Reproductive toxicity (two-generation reproductive toxicity) | 25/06/2012 | 09/08/2012 | Details | |
Hydrocarbons, C14-C18, n-alkanes, isoalkanes, cyclics, aromatics (2-30 %) | 920-360-0 | - | Reproductive toxicity (two-generation reproductive toxicity) | 25/06/2012 | 09/08/2012 | Details | |
Hydrocarbons, C10-C14, n-alkanes, isoalkanes, <2% aromatics | 920-274-3 | - | Reproductive toxicity (two-generation reproductive toxicity) | 25/06/2012 | 09/08/2012 | Details | |
Hydrocarbons, C9-C11, isoalkanes, cyclics | 920-134-1 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
21/01/2021 21/01/2021 21/01/2021 |
08/03/2021 08/03/2021 08/03/2021 |
Details | |
Hydrocarbons, C9-C11, isoalkanes, cyclics, <2% aromatics | 920-134-1 | - | Reproductive toxicity (two-generation reproductive toxicity) | 25/06/2012 | 09/08/2012 | Details | |
Hydrocarbons, C14-C19, isoalkanes, cyclics, <2% aromatics | 920-114-2 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
21/01/2021 21/01/2021 21/01/2021 |
08/03/2021 08/03/2021 08/03/2021 |
Details | |
Hydrocarbons, C14-C19, isoalkanes, cyclics, <2% aromatics | 920-114-2 | - | Reproductive toxicity (two-generation reproductive toxicity) | 25/06/2012 | 09/08/2012 | Details | |
Hydrocarbons, C12-C15, n-alkanes, isoalkanes, cyclics, < 2% aromatics | 920-107-4 | - | Reproductive toxicity (two-generation reproductive toxicity) | 25/06/2012 | 09/08/2012 | Details | |
Hydrocarbons, C9-C11, n-alkanes, isoalkanes, cyclics, <2% aromatics | 919-857-5 | - | Reproductive toxicity (two-generation reproductive toxicity) | 25/06/2012 | 09/08/2012 | Details | |
Esterification products of 4,4'-Isopropylidenediphenol, ethoxylated and prop-2-enoic acid and 3,5,5-trimethylhexanoic acide | 919-846-5 | - |
Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with an analogous substance Sub-chronic toxicity (90-day): oral |
31/08/2015 31/08/2015 |
15/10/2015 15/10/2015 |
Details | |
Hydrocarbons, C9-C12, n-alkanes, isoalkanes, cyclics, aromatics (2-25%) | 919-446-0 | - | Reproductive toxicity (two-generation reproductive toxicity) | 25/06/2012 | 09/08/2012 | Details | |
Hydrocarbons, C10-C13, n-alkanes, isoalkanes, cyclics, aromatics (2-25%) | 919-164-8 | - | Reproductive toxicity (two-generation reproductive toxicity) | 25/06/2012 | 09/08/2012 | Details | |
Hydrocarbons, C10-C13, n-alkanes, isoalkanes, cyclics, aromatics (2-25%) | 919-164-8 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
21/01/2021 21/01/2021 21/01/2021 |
08/03/2021 08/03/2021 08/03/2021 |
Details | |
Hydrocarbons, C16-C20, n-alkanes, isoalkanes, cyclics, <2% aromatics | 919-029-3 | - | Reproductive toxicity (two-generation reproductive toxicity) | 25/06/2012 | 09/08/2012 | Details | |
Hydrocarbons, C16-C20, n-alkanes, isoalkanes, cyclics, aromatics (2-30 %) | 919-006-8 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
21/01/2021 21/01/2021 21/01/2021 |
08/03/2021 08/03/2021 08/03/2021 |
Details | |
Hydrocarbons, C16-C20, n-alkanes, isoalkanes, cyclics, aromatics (2-30 %) | 919-006-8 | - | Reproductive toxicity (two-generation reproductive toxicity) | 25/06/2012 | 09/08/2012 | Details | |
Hydrocarbons, C13-C16, isoalkanes, cyclics, <2% aromatics | 918-973-3 | - | Reproductive toxicity (two-generation reproductive toxicity) | 25/06/2012 | 09/08/2012 | Details | |
Hydrocarbons, C10-C13, n-alkanes, isoalkanes, cyclics, < 2% aromatics | 918-481-9 | - | Reproductive toxicity (two-generation reproductive toxicity) | 25/06/2012 | 09/08/2012 | Details | |
Hydrocarbons, C10-C13, isoalkanes, cyclics, <2% aromatics | 918-317-6 | - | Reproductive toxicity (two-generation reproductive toxicity) | 25/06/2012 | 09/08/2012 | Details | |
Hydrocarbons, C11-C12, isoalkanes, < 2% aromatics | 918-167-1 | - | Reproductive toxicity (two-generation reproductive toxicity) | 25/06/2012 | 09/08/2012 | Details | |
Hydrocarbons, C14-C17, n-alkanes, <2% aromatics | 917-828-1 | - | Reproductive toxicity (two-generation reproductive toxicity) | 25/06/2012 | 09/08/2012 | Details | |
Hydrocarbons, C14-C17, n-alkanes, <2% aromatics | 917-828-1 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with two substances in a group: Icosane (EC 204-018-1) and Hydrocarbons, C14-C19, isoalkanes, cyclics, < 2% aromatics (920-114-2) | 02/11/2018 | 17/12/2018 | Details | |
Hydrocarbons, C13-C15, n-alkanes, isoalkanes, cyclics, < 2% aromatics | 917-488-4 | - | Reproductive toxicity (two-generation reproductive toxicity) | 25/06/2012 | 09/08/2012 | Details | |
Reaction mass of 2,7-Naphthalenedisulfonic acid, 5-amino-3-[[4-[2-[4-[(7-amino-1-hydroxy-3-sulfo-2-naphthalenyl)azo]-2-sulfophenyl]ethenyl]-3-sulfophenyl]azo]-4-hydroxy-, compd. with 2,2',2''-nitrilotris[ethanol] (1:5) and 3,3'-[ethylenebis[(3-sulpho-p-phenylene)azo]]bis[5-amino-4-hydroxynaphthalene-2,7-disulphonic] acid, compound with 2,2',2''-nitrilotriethanol (1:6) and 3,3'-[vinylenebis[(3-sulpho-p-phenylene)azo]]bis[6-amino-4-hydroxynaphthalene-2-sulphonic] acid, compound with 2,2',2''-nitrilotriethanol (1:4) | 916-899-6 | - | Sub-chronic toxicity (90-day): oral | 10/08/2018 | 24/09/2018 | Details | |
Reaction products of tetrazotized 5-amino-2-[(E)-2-(4-amino-2-sulfophenyl)ethenyl]benzenesulfonic acid with 6-amino-4-hydroxynaphthalene-2-sulfonic acid and 4-amino-5-hydroxynaphthalene-2,7-disulfonic acid in 2-[bis(2-hydroxyethyl)amino]ethanol | 916-899-6 | - | Genetic toxicity in vivo | 16/12/2020 | 01/02/2021 | Details | |