Previous Testing Proposals

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

Showing 501 - 550 of 2,011 results.

Name	EC Number	CAS Number	Hazard endpoint for which vertebrate testing was proposed	Date of publication to call for available information	Deadline for submitting information
5,5'-dithiodi-1,3,4-thiadiazole-2(3H)-thione	276-763-0	72676-55-2	Long-term toxicity to fish	30/06/2023	14/08/2023	Details
5,5'-dithiodi-1,3,4-thiadiazole-2(3H)-thione	276-763-0	72676-55-2	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/12/2020 16/12/2020	01/02/2021 01/02/2021	Details
5,5'-dithiodi-1,3,4-thiadiazole-2(3H)-thione	276-763-0	72676-55-2	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant	20/10/2016	05/12/2016	Details
5-amino-2-nitrobenzoic acid	236-283-4	13280-60-9	Genetic toxicity in vivo	25/01/2022	11/03/2022	Details
5-bromo-5-nitro-1,3-dioxane	250-001-7	30007-47-7	Genetic toxicity in vivo	19/10/2020	03/12/2020	Details
5-ethyl-1,3-dioxane-5-methanol	225-967-8	5187-23-5	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	31/01/2014 31/01/2014	17/03/2014 17/03/2014	Details
5-ethyl-1,3-dioxane-5-methanol	225-967-8	5187-23-5	Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	03/10/2023 03/10/2023 03/10/2023	17/11/2023 17/11/2023 17/11/2023	Details
5-Methoxy-2-tetralone	457-080-9	-	Genetic toxicity in vivo	06/09/2018	22/10/2018	Details
5-methylheptan-3-one	208-793-7	541-85-5	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): inhalation	03/03/2014 03/03/2014	17/04/2014 17/04/2014	Details
5-methylhexan-2-one	203-737-8	110-12-3	Reproductive toxicity (pre-natal developmental toxicity)	14/02/2011	31/03/2011	Details
5-sulphosalicylic acid	202-555-6	97-05-2	Genetic toxicity in vivo	10/05/2022	27/06/2022	Details
6'-(dibutylamino)-3'-methyl-2'-(phenylamino)spiro[isobenzofuran-1(3H),9-(9H)-xanthen]-3-one	403-830-5	89331-94-2	Sub-chronic toxicity (90-day): oral	26/03/2018	11/05/2018	Details
6'-(dibutylamino)-3'-methyl-2'-(phenylamino)spiro[isobenzofuran-1(3H),9-(9H)-xanthen]-3-one	403-830-5	89331-94-2	Bioaccumulation aquatic / sediment	12/06/2015	27/07/2015	Details
6'-(dibutylamino)-3'-methyl-2'-(phenylamino)spiro[isobenzofuran-1(3H),9-(9H)-xanthen]-3-one	403-830-5	89331-94-2	Bioaccumulation aquatic / sediment Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	23/04/2018 23/04/2018 23/04/2018	07/06/2018 07/06/2018 07/06/2018	Details
6'-(dibutylamino)-3'-methyl-2'-(phenylamino)spiro[isobenzofuran-1(3H),9-(9H)-xanthen]-3-one	403-830-5	89331-94-2	Sub-chronic toxicity (90-day): oral	02/09/2013	18/10/2013	Details
6,15-dihydroanthrazine-5,9,14,18-tetrone	201-375-5	81-77-6	Reproductive toxicity (pre-natal developmental toxicity)	14/08/2014	28/09/2014	Details
6,6'-di-tert-butyl-2,2'-methylenedi-p-cresol	204-327-1	119-47-1	Reproductive toxicity (extended one-generation reproductive toxicity study)	23/04/2018	07/06/2018	Details
6,6`-di-tert-butyl-2,2`-methylenedi-p-cresol	204-327-1	119-47-1	Reproductive toxicity (two-generation reproductive toxicity)	16/05/2011	30/06/2011	Details
6,8-Dioxabicyclo[3.2.1]octan-4-one, (1S,5R) (Cyrene)	807-130-4	53716-82-8	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	26/08/2021 26/08/2021	11/10/2021 11/10/2021	Details
6-(cyclohexylamino)-3-methyl-3H-dibenz[f,ij]isoquinoline-2,7-dione	244-320-0	21295-57-8	Genetic toxicity in vivo	26/08/2021	11/10/2021	Details
6-(isononanoylamino)hexanoic acid, compound with 2,2',2''-nitrilotriethanol (1:1)	701-138-0	242482-67-3	Reproductive toxicity (pre-natal developmental toxicity)	01/09/2017	16/10/2017	Details
6-[(1-oxomethyloctyl)amino]hexanoic acid	276-173-3	71902-23-3	Reproductive toxicity (pre-natal developmental toxicity)	10/03/2017	25/04/2017	Details
6-methyl-1,3,5-triazine-2,4-diyldiamine	208-796-3	542-02-9	Reproductive toxicity (pre-natal developmental toxicity)	21/03/2014	05/05/2014	Details
6-phenyl-1,3,5-triazine-2,4-diamine	202-095-6	91-76-9	Reproductive toxicity (two-generation reproductive toxicity) Reproductive toxicity (pre-natal developmental toxicity)	12/06/2013	29/07/2013	Details
6-tert-butyl-2,4-xylenol	217-533-1	1879-09-0	Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity)	18/02/2021 18/02/2021	05/04/2021 05/04/2021	Details
6-tert-butyl-2,4-xylenol	217-533-1	1879-09-0	Long-term toxicity to fish	15/07/2014	29/08/2014	Details
7,7,9(or 7,9,9)-trimethyl-4,13-dioxo-3,14-dioxa-5,12-diazahexadecane-1,16-diyl bismethacrylate	276-957-5	72869-86-4	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant	19/10/2020	03/12/2020	Details
7-amino-3,8-bis-[4-(2-sulfoxyethylsulfonyl)-2-sulfophenylazo]-4-hydroxynaphthalene-2-sulfonic acid, Na/K salt; 7-amino-3-[4-(2-sulfoxyethylsulfonyl)phenylazo]-4-hydroxy-8-[4-(2-sulfoxyethylsulfonyl)-2-sulfophenylazo]naphthalene-2-sulfonic acid, Na/K salt; 7-amino-8-[4-(2-sulfoxyethylsulfonyl)-phenylazo]-4-hydroxy-3-[4-(2-sulfoxyethylsulfonyl)-2-sulfophenylazo]naphthalene-2-sulfonic acid, Na/K salt; reaction mass of: 7-amino-3,8-bis-[4-(2-sulfoxyethylsulfonyl)phenylazo]-4-hydroxynaphthalene-2-sulfonic acid, Na/K salt	429-070-4	-	Sub-chronic toxicity (90-day): oral	22/04/2021	07/06/2021	Details
7-hydroxycitronellal	203-518-7	107-75-5	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	31/01/2023 31/01/2023 31/01/2023	17/03/2023 17/03/2023 17/03/2023	Details
8,9,10,11-tetrachloro-12H-phthaloperin-12-one	244-007-9	20749-68-2	Reproductive toxicity (pre-natal developmental toxicity)	14/08/2014	28/09/2014	Details
8,9,10-trinorborn-2-ene	207-866-0	498-66-8	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/06/2011 16/06/2011	01/08/2011 01/08/2011	Details
8,9,10-trinorborn-2-ene	207-866-0	498-66-8	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	01/11/2015 01/11/2015	16/12/2015 16/12/2015	Details
9-Octadecenoic acid (Z)-, sulfonated, potassium salts	271-843-1	68609-93-8	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	16/02/2015 16/02/2015 16/02/2015	02/04/2015 02/04/2015 02/04/2015	Details
[1,3(or 1,4)-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide	246-678-3	25155-25-3	Reproductive toxicity (extended one-generation reproductive toxicity study)	27/05/2019	11/07/2019	Details
[1,3(or 1,4)-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide	246-678-3	25155-25-3	Bioaccumulation aquatic / sediment Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	06/03/2012 06/03/2012 06/03/2012	20/04/2012 20/04/2012 20/04/2012	Details
[1,3(or 1,4)-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide	246-678-3	25155-25-3	Reproductive toxicity (pre-natal developmental toxicity)	30/11/2015	14/01/2016	Details
[1,3-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide	218-664-7	2212-81-9	Bioaccumulation aquatic / sediment Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: Testing proposal is based on concern identified by the registrant	20/10/2016 20/10/2016	05/12/2016 05/12/2016	Details
[1,3-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide	218-664-7	2212-81-9	Reproductive toxicity (extended one-generation reproductive toxicity study) “\|\| Note: testing proposed with [1,3(or 1,4)-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide CAS: 25155-25-3)”	25/05/2020	09/07/2020	Details
[1,3-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide	218-664-7	2212-81-9	Bioaccumulation aquatic / sediment Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/05/2012 16/05/2012 16/05/2012	02/07/2012 02/07/2012 02/07/2012	Details
[1R-(1α,2β,5α)]-1-(isopropyl)-2-methoxy-4-methylcyclohexane	216-365-6	1565-76-0	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant	19/10/2020	03/12/2020	Details
[1α(E),2β]-1-(2,6,6-trimethylcyclohex-3-en-1-yl)but-2-en-1-one	275-156-8	71048-82-3	Reproductive toxicity (pre-natal developmental toxicity)	26/10/2022	12/12/2022	Details
[3-(2,3-epoxypropoxy)propyl]diethoxymethylsilane	220-780-8	2897-60-1	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant.	16/12/2016	30/01/2017	Details
[3-(2,3-epoxypropoxy)propyl]triethoxysilane	220-011-6	2602-34-8	Genetic toxicity in vivo	18/03/2021	03/05/2021	Details
[3-(2,3-epoxypropoxy)propyl]trimethoxysilane	219-784-2	2530-83-8	6.1.2 Long-term toxicity to fish 7.8.1 Toxicity to reproduction	08/03/2024 08/03/2024	22/04/2024 22/04/2024	Details
[3-(2,3-epoxypropoxy)propyl]trimethoxysilane	219-784-2	2530-83-8	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant	17/06/2020	03/08/2020	Details
[3-(2,3-epoxypropoxy)propyl]trimethoxysilane	219-784-2	2530-83-8	Genetic toxicity in vivo	16/02/2015	02/04/2015	Details
[3-(2,3-epoxypropoxy)propyl]trimethoxysilane	219-784-2	2530-83-8	Genetic toxicity in vivo	01/08/2012	17/09/2012	Details
[3-(triethoxysilyl)propyl]urea	245-876-7	23779-32-0	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	17/04/2015 17/04/2015	04/06/2015 04/06/2015	Details
[3-(trimethoxysilyl)propyl]urea	245-904-8	23843-64-3	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Urea, N-(3-silylpropyl)-, Si-(ethoxy and methoxy) derivs., (EC 601-461-6) \|\| Note: Testing proposal is based on concern identified by the registrant	07/07/2020	21/08/2020	Details
[3aR-(3aα,5aβ,9aα,9bβ)]-dodecahydro-3a,6,6,9a-tetramethylnaphtho[2,1-b]furan	229-861-2	6790-58-5	Long-term toxicity to fish	22/09/2022	07/11/2022	Details

Showing 501 - 550 of 2,011 results.

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