Previous Testing Proposals

Previous Testing Proposals

Previous Testing Proposals

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

There are currently no ongoing consultations.
 
Extracts (petroleum), deasphalted vacuum residue solvent 295-332-8 91995-70-9
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): dermal
28/02/2019
28/02/2019
28/02/2019
15/04/2019
15/04/2019
15/04/2019
Details
Extracts (petroleum), deasphalted vacuum residue solvent 295-332-8 91995-70-9 Reproductive toxicity (two-generation reproductive toxicity) 29/07/2011 12/09/2011 Details
3-aminopropyltriethoxysilane 213-048-4 919-30-2
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
18/03/2021
18/03/2021
03/05/2021
03/05/2021
Details
Sodium 1-hydroxyethanesulphonate 213-037-4 918-04-7 Genetic toxicity in vivo 25/05/2020 09/07/2020 Details
Cobalt, borate propionate complexes 295-033-2 91782-61-5
Carcinogenicity || Note: testing proposed with Cobalt dichloride (EC 231-589-4) || Note: Testing proposal is based on concern identified by the registrant.
Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2) || Note: Testing proposal is based on concern identified by the registrant.
21/09/2020
21/09/2020
05/11/2020
05/11/2020
Details
Cobalt, borate 2-ethylhexanoate complexes 295-032-7 91782-60-4
Carcinogenicity || Note: testing proposed with Cobalt dichloride (EC 231-589-4) || Note: Testing proposal is based on concern identified by the registrant
Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2) || Note: Testing proposal is based on concern identified by the registrant
07/07/2020
07/07/2020
21/08/2020
21/08/2020
Details
Tar, wood 294-436-0 91722-33-7 Reproductive toxicity (pre-natal developmental toxicity) 23/02/2022 12/04/2022 Details
Resin acids and Rosin acids, maleated, calcium salts 294-402-5 91722-01-9
Reproductive toxicity (pre-natal developmental toxicity) //Note: to be tested with Rosin, maleated (CAS RN 8050-28-0)
Sub-chronic toxicity (90-day): oral //Note: Testing proposed with Rosin, fumarated (CAS RN 65997-04-7) and Rosin, maleated (CAS RN 8050-28-0)
02/07/2013
02/07/2013
16/08/2013
16/08/2013
Details
1,3-Propanediol, 2,2-bis(hydroxymethyl)-, allyl ether 293-883-9 91648-24-7 Bioaccumulation aquatic / sediment || Note: Testing proposal is based on concern identified by the registrant. 23/11/2020 07/01/2021 Details
1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-C12-14 acyl derivs., hydroxides, inner salts 293-878-1 91648-19-0
Long-term toxicity to fish || Note: testing proposed with 1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C12-18(even numbered) acyl) derivs., hydroxides, inner salts (EC 939-457-4)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C8-18(even numbered) acyl) derivs., hydroxides, inner salts (EC 939-455-3)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with 1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C8-18(even numbered) acyl) derivs., hydroxides, inner salts (EC 939-455-3)
18/06/2018
18/06/2018
18/06/2018
02/08/2018
02/08/2018
02/08/2018
Details
Dialkyl-methyl-dihydro-heteropolycyle 815-131-6 913171-06-9 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 23/03/2020 07/05/2020 Details
Rosin, reaction products with formaldehyde 293-659-0 91081-53-7
Reproductive toxicity (pre-natal developmental toxicity) //Note: testing proposed with Rosin (CAS RN 8050-09-7)
Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with _ Rosin (CAS RN 8050-09-7)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Rosin (CAS RN 8050-09-7), Rosin, hydrogenated (CAS RN 65997-06-0), Rosin, reaction products with formaldehyde (CAS RN 91081-53-7)
19/07/2013
02/07/2013
02/07/2013
02/09/2013
16/08/2013
16/08/2013
Details
Rosin, reaction products with formaldehyde 293-659-0 91081-53-7 Reproductive toxicity (pre-natal developmental toxicity) 06/03/2012 20/04/2012 Details
Hydrocarbons, C4, 1,3-butadiene-free, polymd., triisobutylene fraction 293-263-8 91053-01-9
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with Butene, homopolymer (products derived from either/or But-1-ene/But-2-ene) (EC no. 500-004-7)
Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Butene, homopolymer (products derived from either/or But-1-ene/But-2-ene) (EC no. 500-004-7)
Sub-chronic toxicity (90-day): oral||Note: testing proposed with Butene, homopolymer (products derived from either/or But-1-ene/But-2-ene) (EC no. 500-004-7)
06/06/2023
06/06/2023
06/06/2023
21/07/2023
21/07/2023
21/07/2023
Details
Fatty acids, C16-18, reaction products with diethanolamine 293-014-3 91032-08-5 Reproductive toxicity (pre-natal developmental toxicity) 16/03/2015 30/04/2015 Details
Fatty acids, C16-18, isononyl esters 292-960-4 91031-57-1
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
30/06/2023
30/06/2023
30/06/2023
14/08/2023
14/08/2023
14/08/2023
Details
Fatty acids, C16-18, barium salts 292-883-6 91002-07-2 Long-term toxicity to fish //Note: testing to be done with barium dichloride (CAS number 10361-37-2) 04/04/2014 19/05/2014 Details
6-phenyl-1,3,5-triazine-2,4-diamine 202-095-6 91-76-9 Reproductive toxicity (two-generation reproductive toxicity) Reproductive toxicity (pre-natal developmental toxicity) 12/06/2013 29/07/2013 Details
decahydronaphthalene 202-046-9 91-17-8 Reproductive toxicity (two-generation reproductive toxicity) 15/07/2011 29/08/2011 Details
Decahydronaphthalene 202-046-9 91-17-8 Reproductive toxicity (extended one-generation reproductive toxicity study) 23/04/2018 07/06/2018 Details
3,5-diamino-4-[[4-[[2-(sulfooxy)ethyl]sulfonyl]phenyl]azo]-2-[[2-sulfo-4-[[2-(sulfooxy)ethyl]sulfonyl]phenyl]azo]benzoic acid sodium salt 480-890-9 906532-68-1 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant 18/11/2014 02/01/2015 Details
Amines, polyethylenepoly-, tetraethylenepentamine fraction 292-587-7 90640-66-7
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with TETA (CAS 90640-67-8) and HEPA (68121-73-7)
Reproductive toxicity (pre-natal developmental toxicity )
31/01/2018
31/01/2018
19/03/2018
19/03/2018
Details
Amines, polyethylenepoly-, tetraethylenepentamine fraction 292-587-7 90640-66-7 Reproductive toxicity (extended one-generation reproductive toxicity study) 01/11/2015 16/12/2015 Details
Amines, polyethylenepoly-, triethylenetetramine fraction 292-588-2 90640-66-7
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
22/11/2017
22/11/2017
08/01/2018
08/01/2018


Details
Amines, polyethylenepoly-, triethylenetetramine fraction,Triethylenetetramine linear, cyclic and branched 292-588-2 90640-66-7
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
01/09/2017
01/09/2017
16/10/2017
16/10/2017
Details
Amines, polyethylenepoly-, triethylenetetramine fraction,Triethylenetetramine linear, cyclic and branched 292-588-2 90640-66-7 Reproductive toxicity (two-generation reproductive toxicity) 05/04/2011 20/05/2011 Details
Alkanes, C12-26-branched and linear 292-454-3 90622-53-0 Reproductive toxicity (two-generation reproductive toxicity) 15/09/2011 31/10/2011 Details
Alkenes, C13-14, hydroformylation products, distn. residues 292-429-7 90622-29-0 Reproductive toxicity (extended one-generation reproductive toxicity study) “|| Note: testing proposed with Alkenes, C11-12, hydroformylation products, distn. residues (EC 292-427-6) 02/11/2018 17/12/2018 Details
Alkenes, C13-14, hydroformylation products, distn. Residues 292-429-7 90622-29-0
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
15/09/2011
15/09/2011
15/09/2011
31/10/2011
31/10/2011
31/10/2011
Details
Alkenes, C11-12, hydroformylation products, distn. residues 292-427-6 90622-27-8
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
15/09/2011
15/09/2011
15/09/2011
31/10/2011
31/10/2011
31/10/2011
Details
Alkenes, C11-12, hydroformylation products, distn. Residues 292-427-6 90622-27-8 Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018 Details
1,5-Pentanediamine, 2-methyl-, reaction products with 2-ethyl-1,4-butanediamine and glycidyl tolyl ether 291-813-1 90480-76-5
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
19/10/2020
19/10/2020
03/12/2020
03/12/2020
Details
Hydrochloric acid, reaction products with aniline and nitrobenzene, sulfonated, sodium salts 291-454-0 90411-76-0 Reproductive toxicity (pre-natal developmental toxicity) 30/11/2015 14/01/2016 Details
2,5-bis(1,1,3,3-tetramethylbutyl)hydroquinone 212-990-3 903-19-5 Genetic toxicity in vivo 16/12/2020 01/02/2021 Details
1,2,4-Benzenetricarboxylic acid, mixed decyl and octyl triesters 290-754-9 90218-76-1 Sub-chronic toxicity (90-day): oral 29/07/2011 12/09/2011 Details
2,4,7,9-Tetramethyldec-5-yne-4,7-diol, ethoxylated 500-022-5 9014-85-1 Reproductive toxicity (pre-natal developmental toxicity)

|| Note: testing proposed with 2,4,7,9-Tetramethyl-5-decyne-4,7-diol (CAS number 126-86-3) ||
25/11/2019 09/01/2020 Details
2,2'-isopropylidenebis(p-phenyleneoxy)diethanol 212-985-6 901-44-0 Long-term toxicity to fish 22/09/2022 07/11/2022 Details
2,2'-isopropylidenebis(p-phenyleneoxy)diethanol 212-985-6 901-44-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
27/01/2020
27/01/2020
12/03/2020
12/03/2020
Details
Resin acids and Rosin acids, calcium salts 232-694-8 9007-13-0 Reproductive toxicity (pre-natal developmental toxicity) 06/03/2012 20/04/2012 Details
Resin acids and Rosin acids, calcium salts 232-694-8 9007-13-0
Reproductive toxicity (pre-natal developmental toxicity || Note: Testing proposed with Rosin CAS 8050-09-7
Reproductive toxicity (two-generation reproductive toxicity) || Note: Testing proposed with Rosin CAS 8050-09-7
Sub-chronic toxicity (90-day): oral || Note: Testing proposed with Rosin CAS 8050-09-7, Rosin hydrogenated CAS 65997-06-0, and Rosin reaction products with formaldehyde CAS 91081-53-7
02/07/2013
02/07/2013
02/07/2013
16/08/2013
16/08/2013
16/08/2013
Details
Poly(oxy-1,2-ethanediyl), α-butyl-ω-hydroxy- 500-012-0 9004-77-7
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with 2-(2-(2-methoxyethoxy)ethoxy)ethanol (EC 203-962-1).
Reproductive toxicity (pre-natal developmental toxicity) – rabbits
|| Note: testing proposed with 2-(2-(2-butoxyethoxy)ethoxy)ethanol (EC 205-592-6)
Reproductive toxicity (pre-natal developmental toxicity) – rats-
|| Note: testing proposed with 2-(2-(2-butoxyethoxy)ethoxy)ethanol (EC 205-592-6)
27/01/2020
27/01/2020
27/01/2020
12/03/2020
12/03/2020
12/03/2020
Details
Butene, homopolymer (products derived from either/or But-1-ene/But-2-ene) 500-004-7 9003-29-6
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
06/06/2023
06/06/2023
06/06/2023
21/07/2023
21/07/2023
21/07/2023
Details
2-(4-fluorophenyl)-5-(5-iodo-2-methylbenzyl)thiophene 618-312-6 898566-17-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
31/01/2018
31/01/2018
19/03/2018
19/03/2018
Details
6'-(dibutylamino)-3'-methyl-2'-(phenylamino)spiro[isobenzofuran-1(3H),9-(9H)-xanthen]-3-one 403-830-5 89331-94-2 Sub-chronic toxicity (90-day): oral 26/03/2018 11/05/2018 Details
6'-(dibutylamino)-3'-methyl-2'-(phenylamino)spiro[isobenzofuran-1(3H),9-(9H)-xanthen]-3-one 403-830-5 89331-94-2 Bioaccumulation aquatic / sediment 12/06/2015 27/07/2015 Details
6'-(dibutylamino)-3'-methyl-2'-(phenylamino)spiro[isobenzofuran-1(3H),9-(9H)-xanthen]-3-one 403-830-5 89331-94-2
Bioaccumulation aquatic / sediment
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
23/04/2018
23/04/2018
23/04/2018
07/06/2018
07/06/2018
07/06/2018
Details
6'-(dibutylamino)-3'-methyl-2'-(phenylamino)spiro[isobenzofuran-1(3H),9-(9H)-xanthen]-3-one 403-830-5 89331-94-2 Sub-chronic toxicity (90-day): oral 02/09/2013 18/10/2013 Details
pentasodium 5-{[4-chloro-6-({4-[2-(sulfooxy)ethanesulfonyl]phenyl}amino)-1,3,5-triazin-2-yl]amino}-3-[2-(1,5-disulfonaphthalen-2-yl)diazen-1-yl]-4-hydroxynaphthalene-2,7-disulfonate 402-420-3 89157-03-9 Sub-chronic toxicity (90-day): oral 25/06/2019 09/08/2019 Details
Thymol 201-944-8 89-83-8
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
16/06/2022
16/06/2022
01/08/2022
01/08/2022
Details
Menthol 201-939-0 89-78-1 Reproductive toxicity (extended one-generation reproductive toxicity study) 01/09/2017 16/10/2017 Details