Previous Testing Proposals
Previous Testing Proposals
Previous Testing Proposals
This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.
Further instructions
To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.
There are currently no ongoing consultations.
| 3,9-dicyclohex-3-enyl-2,4,8,10-tetraoxaspiro[5.5]undecane | 229-542-8 | 6600-31-3 | Reproductive toxicity (pre-natal developmental toxicity) | 15/07/2014 | 29/08/2014 | Details | |
| 6-tert-butyl-2,4-xylenol | 217-533-1 | 1879-09-0 | Long-term toxicity to fish | 15/07/2014 | 29/08/2014 | Details | |
| d-Glucose, ether with glycerol | 309-496-6 | 100402-60-6 | Reproductive toxicity (pre-natal developmental toxicity) | 15/07/2014 | 29/08/2014 | Details | |
| Fatty acids, tall-oil, reaction products with formaldehyde and (Z)-N-9-octadecenyl-1,3-propanediamine | 272-789-1 | 68911-83-1 | Reproductive toxicity (two-generation reproductive toxicity) || Note: Testing proposal is based on concern identified by the registrant. | 15/07/2014 | 29/08/2014 | Details | |
| Halophosphate | - | - | Sub-chronic toxicity (90 day): inhalation | 15/07/2014 | 29/08/2014 | Details | |
| Poly [oxy(methyl-1,2-ethanediyl)] , a -hydro-w -hydroxy-, ether with 2-ethyl-2-(hydroxymethyl)-1,3-propanediol (3:1), 3-[[3-dimethylamino) propyl]imino]butanoate | 613-645-3 | 646505-36-4 | Reproductive toxicity (pre-natal developmental toxicity) | 15/07/2014 | 29/08/2014 | Details | |
| Sodium xylenesulphonate | 215-090-9 | 1300-72-7 | Reproductive toxicity (two-generation reproductive toxicity) | 15/07/2014 | 29/08/2014 | Details | |
| sodium/triethanolamine 4-((2-hydroxyethyl)amino)-3-pentaproenyl-4-oxobutanoate | 800-765-8 | 1424149-03-0 | Reproductive toxicity (pre-natal developmental toxicity) | 15/07/2014 | 29/08/2014 | Details | |
| tert-butyl peroxyisobutyrate | 203-650-5 | 109-13-7 | Genetic toxicity in vivo | 15/07/2014 | 29/08/2014 | Details | |
| p-tert-butylphenyl 1-(2,3-epoxy)propyl ether | 221-453-2 | 3101-60-8 |
Sub-chronic toxicity (90-day): oral Reproductive toxicity (two-generation reproductive toxicity) Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) |
17/06/2014 17/06/2014 17/06/2014 17/06/2014 |
01/08/2014 01/08/2014 01/08/2014 01/08/2014 |
Details | |
| 2-aminopropane-1,3-diol | 208-584-0 | 534-03-2 |
Sub-chronic toxicity (90 day): oral Reproductive toxicity (pre-natal developmental toxicity) |
17/06/2014 17/06/2014 |
01/08/2014 01/08/2014 |
Details | |
| Reaction mass of 4,4,13,13-tetraethoxy-3,14-dioxa-8,9-dithia-4,13-disilahexadecane and 4,4,14,14-tetraethoxy-3,15-dioxa-8,9,10-trithia-4,14-disilaheptadecane | 915-748-1 | - |
Reproductive toxicity (pre-natal developmental toxicity) // Note: testing proposed with (CAS 211519-85-6) Reproductive toxicity (two-generation reproductive toxicity) // Note: testing proposed with (CAS 211519-85-6) |
17/06/2014 17/06/2014 |
01/08/2014 01/08/2014 |
Details | |
| Reaction product of naphthalene, propan-2-ol, sulfonated and neutralized by caustic soda | 939-368-0 | - |
Sub-chronic toxicity (90-day): inhalation Reproductive toxicity (pre-natal developmental toxicity) |
17/06/2014 17/06/2014 |
01/08/2014 01/08/2014 |
Details | |
| tert-butyl peroxyneodecanoate | 247-955-1 | 26748-41-4 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
17/06/2014 17/06/2014 |
01/08/2014 01/08/2014 |
Details | |
| Trometamol | 201-064-4 | 77-86-1 |
Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with 2-amino-1,3-propanediol Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with 2-amino-1,3-propanediol |
17/06/2014 17/06/2014 |
01/08/2014 01/08/2014 |
Details | |
| 4,4'-isopropylidenedicyclohexanol | 201-244-2 | 80-04-6 | Long-term toxicity to fish | 17/06/2014 | 01/08/2014 | Details | |
| Disodium oxybis[methylbenzenesulphonate] | 277-242-0 | 73037-34-0 | Reproductive toxicity (pre-natal developmental toxicity) | 17/06/2014 | 01/08/2014 | Details | |
| Hydroxyethylated 2-butyne-1,4-diol | 608-711-3 | 32167-31-0 | Sub-chronic toxicity (90-day): oral | 17/06/2014 | 01/08/2014 | Details | |
| Octene, hydroformylation products, low-boiling | 273-110-1 | 68938-03-4 | Genetic toxicity in vivo | 17/06/2014 | 01/08/2014 | Details | |
| Fatty acids, tall-oil, reaction products with diethylenetriamine and maleic anhydride | 800-430-6 | 1419212-76-2 |
Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity) |
05/06/2014 05/06/2014 |
21/07/2014 21/07/2014 |
Details | |
| Fatty acids, tall-oil, reaction products with fatty acids C16-C18 and C18-unsatd, branched and linear, diethylenetriamine and citric acid | 806-510-7 | 1393571-43-1 |
Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Fatty acids, tall-oil, reaction products with diethylenetriamine and maleic anhydride (CAS number: 1419212-76-2, CAS name: Amides, tall-oil fatty, N, N’-(iminodi-2,1-ethanediyl)bis-, maleated) Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with Fatty acids, tall-oil, reaction products with diethylenetriamine and maleic anhydride (CAS number: 1419212-76-2, CAS name: Amides, tall-oil fatty, N, N’-(iminodi-2,1-ethanediyl)bis-, maleated) |
05/06/2014 05/06/2014 |
21/07/2014 21/07/2014 |
Details | |
| Fatty acids, tall-oil, reaction products with fatty acids C16-C18 and C18-unsatd, branched and linear, diethylenetriamine and maleic anhydride | 806-508-6 | 1419212-77-3 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral
Note: testing proposed with substance Fatty acids, tall-oil, reaction products with diethylenetriamine and maleic anhydride (CAS: 1419212-76-2) |
05/06/2014 05/06/2014 |
21/07/2014 21/07/2014 |
Details | |
| Fatty acids, C16-18 and C18-unsatd., branched and linear, reaction products with diethylenetriamine and tall-oil fatty acids, Me maleates | 806-509-1 | 1393571-42-0 | Reproductive toxicity (pre-natal developmental toxicity) | 05/06/2014 | 21/07/2014 | Details | |
| 2-Butenedioic acid (Z)-, ester with 1,2-propanediol, compd. with 2-(dibutylamino)ethanol | 286-304-6 | 85204-10-0 |
Sub-chronic toxicity (90-day): oral Reproductive toxicity (two-generation reproductive toxicity) Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) |
02/06/2014 02/06/2014 02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 17/07/2014 17/07/2014 |
Details | |
| 4,4'-Isopropylidenedicyclohexanol, oligomeric reaction products with 1-chloro-2,3-epoxypropane | 500-070-7 | 30583-72-3 |
Sub-chronic toxicity (90-day): oral Genetic toxicity in vivo Reproductive toxicity (two-generation reproductive toxicity) Reproductive toxicity (pre-natal developmental toxicity) |
02/06/2014 02/06/2014 02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 17/07/2014 17/07/2014 |
Details | |
| 2-ethylhexyl benzoate | 226-641-8 | 5444-75-7 |
Sub-chronic toxicity (90-day): oral Reproductive toxicity (two-generation reproductive toxicity) Reproductive toxicity (pre-natal developmental toxicity) |
02/06/2014 02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 17/07/2014 |
Details | |
| 4,4'-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane, reaction products with fatty acids, C18-unsatd., dimers | 500-180-5 | 67989-52-0 |
Sub-chronic toxicity (90-day): oral Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) |
02/06/2014 02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 17/07/2014 |
Details | |
| Bis(2-chloroethoxy)methane 1,15-dichloro-3,5,8,11,13-penta-oxa pentadecane 1-(2-chloroethoxy)-2-(2-chloroethoxymethoxy)ethane | 940-783-4 | - |
Long-term toxicity to fish Genetic toxicity in vivo Reproductive toxicity (two-generation reproductive toxicity) // Note: test to be performed with analogues substance 1-chloro-2-[(2-chloroethoxy)methoxy]ethane (EC 203-920-2 ) |
02/06/2014 02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 17/07/2014 |
Details | |
| 1,1,3,3-tetramethylbutyl peroxyneodecanoate | 257-077-0 | 51240-95-0 |
Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity) |
02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 |
Details | |
| 2,2,4(or 2,4,4)-Trimethylhexane-1,6-diisocyanate | 915-277-1 | 32052-51-0 |
Sub-chronic toxicity (90-day): inhalation Reproductive toxicity (pre-natal developmental toxicity) |
02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 |
Details | |
| 3-((C9-11-iso,C10-rich)alkyloxy)propan-1-amine | 939-485-7 | - |
Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity) |
02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 |
Details | |
| 3-((C9-11-iso,C10-rich)alkyloxy)propan-1-amine acetate (1:1) | 939-448-5 | - |
Sub-chronic toxicity (90-day): oral
|| Note: Testing proposed with 1-Propanamine, 3-((C9-11-iso-,C10-rich)alkyloxy)- Reproductive toxicity (pre-natal developmental toxicity)
|| Note: Testing proposed with 1-Propanamine, 3-((C9-11-iso-,C10-rich)alkyloxy)- |
02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 |
Details | |
| Copolymer of acetonoxime and 3-isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate | 600-028-9 | 1001254-87-0 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): dermal |
02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 |
Details | |
| Decene, hydroformylation products, high boiling | 935-454-7 | - |
Sub-chronic toxicity (90-day): oral // Note: testing proposed with Alkenes, C11-12, hydroformylation products, distn. residues (CAS: 90622-27-8) Reproductive toxicity (pre-natal developmental toxicity) // Note: testing proposed with Alkenes, C11-12, hydroformylation products, distn. residues (CAS: 90622-27-8) |
02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 |
Details | |
| Diisodecyl sebacate | 249-047-0 | 28473-19-0 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 |
Details | |
| Octene | 246-920-8 | 25377-83-7 |
Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with hex-1-ene |
02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 |
Details | |
| potassium tetrafluoroborate | 237-928-2 | 14075-53-7 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): inhalation |
02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 |
Details | |
| Reaction Mass of Cis-4-(isopropyl) cyclohexanemethanol and Trans-4-(isopropyl) cyclohexanemethanol | 939-719-8 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 |
Details | |
| Reaction product of 2,4-Dinitrotoluene and 2,6-Dinitrotoluene and hydrogen | 939-489-9 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): oral |
02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 |
Details | |
| 2-Propenoic acid, (1-methyl-1,2-ethanediyl) bis[oxy(methyl-2,1-ethanediyl)] ester, reaction products with diethylamine | 601-101-8 | 111497-86-0 | Reproductive toxicity (pre-natal developmental toxicity) | 02/06/2014 | 17/07/2014 | Details | |
| calcium bis(di C8-C10, branched, C9 rich, alkylnaphthalenesulphonate) | 939-717-7 | - | Sub-chronic toxicity (90-day): oral | 02/06/2014 | 17/07/2014 | Details | |
| Hydrocarbons, C14-C17, isoalkanes, cyclics, <2% aromatics | 939-601-6 | - | Reproductive toxicity (two-generation reproductive toxicity) // Note: testing proposed with Icosane (C20 normal alkanes); Hydrocarbons, C14-C19, isoalkane, cyclics, < 2%; Hydrocarbon, C16-C20, normal, isoalkane, cyclics, 2-30% aromatics | 02/06/2014 | 17/07/2014 | Details | |
| Sodium N-(2-carboxyethyl)-N-(2-ethylhexyl)-β-alaninate | 305-318-6 | 94441-92-6 | Reproductive toxicity (pre-natal developmental toxicity) | 02/06/2014 | 17/07/2014 | Details | |
| 2,2-dimethylpropane-1,3-diyl cyclohex-4-ene-1,2-dicarboxylate | 255-180-5 | 41026-17-9 |
Sub-chronic toxicity (90-day): oral Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
16/05/2014 16/05/2014 16/05/2014 16/05/2014 |
30/06/2014 30/06/2014 30/06/2014 30/06/2014 |
Details | |
| Reaction mass of N-[2-(2-oxoimidazolidin-1-yl)ethyl]methacrylamide and methacrylic acid | 934-058-1 | - |
Genetic toxicity in vivo Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/05/2014 16/05/2014 16/05/2014 16/05/2014 |
30/06/2014 30/06/2014 30/06/2014 30/06/2014 |
Details | |
| 1,6-hexanediyl-bis(2-(2-(1-ethylpentyl)-3-oxazolidinyl)ethyl)carbamate | 925-259-5 | 140921-24-0 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/05/2014 16/05/2014 16/05/2014 |
30/06/2014 30/06/2014 30/06/2014 |
Details | |
| 2,3-epoxypropyl o-tolyl ether | 218-645-3 | 2210-79-9 |
Reproductive toxicity (two-generation reproductive toxicity) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/05/2014 16/05/2014 16/05/2014 |
30/06/2014 30/06/2014 30/06/2014 |
Details | |
| 2-[methyl[(nonafluorobutyl)sulphonyl]amino]ethyl acrylate | 266-733-5 | 67584-55-8 |
Reproductive toxicity (two-generation reproductive toxicity) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/05/2014 16/05/2014 16/05/2014 |
30/06/2014 30/06/2014 30/06/2014 |
Details | |
| 1,6-Bis-[(2,2-dimethyl-3-lauroyloxy-propylidene)-amino]hexane | 479-930-8 | 613222-52-9 |
Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity) |
16/05/2014 16/05/2014 |
30/06/2014 30/06/2014 |
Details | |
| 2-[2-(2-ethoxyethoxy)ethoxy]ethyl methacrylate | 254-588-0 | 39670-09-2 |
Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
16/05/2014 16/05/2014 |
30/06/2014 30/06/2014 |
Details | |