Previous Testing Proposals

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

Showing 1,051 - 1,100 of 2,011 results.

Name	EC Number	CAS Number	Hazard endpoint for which vertebrate testing was proposed	Date of publication to call for available information	Deadline for submitting information
Reaction mass of (2S-cis)-tetrahydro-4-methyl-2-(2-methyl-1-propenyl)-2H-pyran and Tetrahydro-4-methyl-2-(2-methylpropen-1-yl)pyran (2R,4R) and Tetrahydro-4-methyl-2-(2-methylpropen-1-yl)pyran (2S,4S) and (2R-cis)-tetrahydro-4-methyl-2-(2-methyl-1-propenyl)-2H-pyran	939-429-1	16409-43-1	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	30/11/2015 30/11/2015	14/01/2016 14/01/2016	Details
(octadecanoato-O)oxoaluminium	236-521-7	13419-15-3	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Aluminum, benzoate C16-18 fatty acid complexes (CAS 94166-87-7)	30/11/2015	14/01/2016	Details
2-ethylhexyl 10-ethyl-4-[[2-[(2-ethylhexyl)oxy]-2-oxoethyl]thio]-4-octyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate	248-227-6	27107-89-7	Genetic toxicity in vivo	30/11/2015	14/01/2016	Details
[1,3(or 1,4)-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide	246-678-3	25155-25-3	Reproductive toxicity (pre-natal developmental toxicity)	30/11/2015	14/01/2016	Details
D-glucopyranose, oligomeric, C10-16 glycosides (even numbered), carboxymethyl ethers, sodium salts	609-542-8	383178-66-3	Reproductive toxicity (pre-natal developmental toxicity)	30/11/2015	14/01/2016	Details
Fats and Glyceridic oils, vegetable, winterized, reaction products with ammonia-ethanolamine reaction products	800-253-4	-	Long-term toxicity to fish \|\| Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates. Link to registration dossier not given as the dossier not yet disseminated.	30/11/2015	14/01/2016	Details
Hydrochloric acid, reaction products with aniline and nitrobenzene, sulfonated, sodium salts	291-454-0	90411-76-0	Reproductive toxicity (pre-natal developmental toxicity)	30/11/2015	14/01/2016	Details
N-{2-[(phenylcarbamoyl)amino]phenyl}benzenesulfonamide	806-543-7	215917-77-4	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant	30/11/2015	14/01/2016	Details
Reaction products of tryglycerides, C8-C18 (even numbered) and C18-unsaturated, glycerine and ethylene oxide	939-459-5	-	Sub-chronic toxicity (90-day): oral	30/11/2015	14/01/2016	Details
8,9,10-trinorborn-2-ene	207-866-0	498-66-8	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (extended one-generation reproductive toxicity study)	01/11/2015 01/11/2015	16/12/2015 16/12/2015	Details
Amines, polyethylenepoly-, tetraethylenepentamine fraction	292-587-7	90640-66-7	Reproductive toxicity (extended one-generation reproductive toxicity study)	01/11/2015	16/12/2015	Details
N-vinylformamide	236-102-9	13162-05-5	Reproductive toxicity (extended one-generation reproductive toxicity study)	01/11/2015	16/12/2015	Details
N,N'-ethane-1,2-diylbis(12-hydroxyoctadecan-1-amide)	204-613-6	123-26-2	Sub-chronic toxicity (90 day): oral Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with: “Octadecanoic acid, 12-hydroxy-, reaction products with ethylenediamine”, CAS 100545-48-0 Long-term toxicity to fish \|\| Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates	30/09/2015 30/09/2015 30/09/2015	16/11/2015 16/11/2015 16/11/2015	Details
Poly[oxy(methyl-1,2-ethanediyl)], a-hydro-omega-hydroxy-, ether with 2,6 bis{[(2-hydroxyethyl)amino]methyl}-4-nonylphenol	614-668-1	68610-97-9	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	30/09/2015 30/09/2015	16/11/2015 16/11/2015	Details
2,2'-[oxybis(methylene)]-bis[2-ethylpropane-1,3-diol]	245-509-0	23235-61-2	Sub-chronic toxicity (90-day): oral	30/09/2015	16/11/2015	Details
dihydro-3-(tripropenyl)furan-2,5-dione	295-556-6	92077-08-2	Reproductive toxicity (pre-natal developmental toxicity)	30/09/2015	16/11/2015	Details
sodium toluene-4-sulphonate	211-522-5	657-84-1	Reproductive toxicity (extended one-generation reproductive toxicity study)	30/09/2015	16/11/2015	Details
tetraethylammonium hydroxide	201-073-3	77-98-5	Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with N,N,N-trimethylmethanaminium chloride (EC 200-880-8; CAS 75-57-0)	30/09/2015	16/11/2015	Details
Esterification products of 4,4'-Isopropylidenediphenol, ethoxylated and prop-2-enoic acid and 3,5,5-trimethylhexanoic acide	919-846-5	-	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with an analogous substance	31/08/2015 31/08/2015	15/10/2015 15/10/2015	Details
Tri(isopropyl)silyl acrylate	457-670-6	157859-20-6	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	31/08/2015 31/08/2015	15/10/2015 15/10/2015	Details
Tri(isopropyl)silyl acrylate	457-670-6	157859-20-6	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	31/08/2015 31/08/2015	15/10/2015 15/10/2015	Details
3-hydroxy-2-(3-hydroxy-2-quinolyl)-1H-inden-1-one	241-753-7	17772-51-9	Reproductive toxicity (pre-natal developmental toxicity)	31/08/2015	15/10/2015	Details
N,N'-(methylenedi-p-phenylene)bis[hexahydro-2-oxo-1H-azepine-1-carboxamide]	258-981-8	54112-23-1	Long-term toxicity to fish Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates.	31/08/2015	15/10/2015	Details
trimethoxyoctylsilane	221-338-7	3069-40-7	Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with triethoxy(2,4,4-trimethylpentyl)silane (CAS 35435-21-3)	07/08/2015	22/09/2015	Details
Urea, N-octyl-N'-[4-[[4-[[(octylamino)carbonyl]amino]phenyl]methyl]phenyl]-Urea, N-[4-[[4[(octadecylamino)carbonyl]amino]phenyl]methyl]phenyl]-N’-octyl	445-760-8	-	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	31/07/2015 31/07/2015	14/09/2015 14/09/2015	Details
1,1'-isopropylidenebis(p-phenyleneoxy)dipropan-2-ol	204-137-9	116-37-0	Reproductive toxicity (pre-natal developmental toxicity)	31/07/2015	14/09/2015	Details
Reaction mass of 1-(2,3-epoxypropoxy)-2,2-bis ((2,3-epoxypropoxy)methyl) butane and 1-(2,3-epoxypropoxy)-2-((2,3-epoxypropoxy)methyl)-2-hydroxymethyl butane	608-489-8	30499-70-8	Sub-chronic toxicity (90-day): oral Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	25/06/2015 25/06/2015 25/06/2015	10/08/2015 10/08/2015 10/08/2015	Details
1,1,1,3,5,5,5-heptamethyltrisiloxane	217-496-1	1873-88-7	Sub-chronic toxicity (90 day): inhalation Note: testing proposed with 1,1,3,3-tetramethyldisiloxane, CAS 3277-26-7. Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with Octamethyltrisiloxane, CAS 107-51-7 and 1,1,3,3-tetramethyldisiloxane, CAS 3277-26-7	25/06/2015 25/06/2015	10/08/2015 10/08/2015	Details
1,1,3,3-tetramethyl-1,3-divinyldisiloxane	220-099-6	2627-95-4	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	25/06/2015 25/06/2015	10/08/2015 10/08/2015	Details
4-trans-Propyl-4-trans-vinyl-[1,1-bicylohexyl]	601-409-2	116020-44-1	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	25/06/2015 25/06/2015	10/08/2015 10/08/2015	Details
dichloro(diphenyl)silane	201-251-0	80-10-4	Sub-chronic toxicity (90-day): oral Note: testing proposed with dimethoxy(diphenyl)silane (EC 229-929-1, CAS 6843-66-9) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with dimethoxy(diphenyl)silane (EC 229-929-1, CAS 6843-66-9)	25/06/2015 25/06/2015	10/08/2015 10/08/2015	Details
dimethoxydiphenylsilane	229-929-1	6843-66-9	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	25/06/2015 25/06/2015	10/08/2015 10/08/2015	Details
N-[3-(dimethoxymethylsilyl)-2-methylpropyl]ethylenediamine	245-642-4	23410-40-4	Sub-chronic toxicity (90-day): oral Note: Testing proposal is based on concern identified by the registrant. Testing proposed with N-(3-(trimethoxysilyl)propyl)ethylenediamine (EC 217-164-6) Reproductive toxicity (pre-natal developmental toxicity) Note: Testing proposal is based on concern identified by the registrant. Testing proposed with N-(3-(trimethoxysilyl)propyl)ethylenediamine (EC 217-164-6)	25/06/2015 25/06/2015	10/08/2015 10/08/2015	Details
N-[3-(dimethoxymethylsilyl)propyl]ethylenediamine	221-336-6	3069-29-2	Sub-chronic toxicity (90-day): oral Note: testing proposed with N-(3-trimethoxysilyl)propyl)ethylenediamine CAS 1760-24-3. Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with N-(3-trimethoxysilyl)propyl)ethylenediamine CAS 1760-24-3.	25/06/2015 25/06/2015	10/08/2015 10/08/2015	Details
Reaction mass of 6-Amino-5-(4-substituted-sulfophenylazo)-1-hydroxy-2-[2-alkoxy-5-alkyl- (substitutedsulfonyl)-phenylazo]-naphthalene-sulfonic acid, potassium/sodium salt and 6-Amino-1-hydroxy-2-[2-alkoxy-5-alkyl- (substitutedsulfonyl)-phenylazo]-5-[sulfo- (substitutedsulfonyl)-phenylazo]-naphthalene-sulfonic acid, potassium/sodium salt	445-040-3	-	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	25/06/2015 25/06/2015	10/08/2015 10/08/2015	Details
Reaction mass of [[(2-hydroxyethyl)imino]dimethylene]bisphosphonic acid, sodium salt and 4-(Phosphonomethyl)-2-hydroxy-2-oxo-1,4,2-oxazaphosphorinane, sodium salt	939-513-8	-	Sub-chronic toxicity (90-day): oral Note: testing proposed either the registered substance or a read-across substance, which would be the acid form of the registered substance Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed either the registered substance or a read-across substance, which would be the acid form of the registered substance	25/06/2015 25/06/2015	10/08/2015 10/08/2015	Details
trichloro(hexadecyl)silane	227-575-2	5894-60-0	Sub-chronic toxicity (90-day): oral Note: testing proposed with hexadecyl(trimethoxy)silane (EC 240-464-3, CAS 16415-12-6) Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with hexadecyl(trimethoxy)silane (EC 240-464-3, CAS 16415-12-6)	25/06/2015 25/06/2015	10/08/2015 10/08/2015	Details
Ureidopropyltrialkoxysilane	449-160-7	116912-64-2	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	25/06/2015 25/06/2015	10/08/2015 10/08/2015	Details
1,1'-dithiobis[hexahydro-2H-azepin-2-one]	245-910-0	23847-08-7	Reproductive toxicity (pre-natal developmental toxicity)	25/06/2015	10/08/2015	Details
A mixture of: cis-tetrahydro-2-isobutyl-4-methylpyran-4-ol; trans-tetrahydro-2-isobutyl-4-methylpyran-4-ol	405-040-6	63500-71-0	Reproductive toxicity (extended one-generation reproductive toxicity study)	25/06/2015	10/08/2015	Details
Aluminum, benzoate C16-18-fatty acids complexes	303-385-6	94166-87-7	Reproductive toxicity (pre-natal developmental toxicity)	25/06/2015	10/08/2015	Details
butan-2-one O,O',O''-(vinylsilylidyne)trioxime	218-747-8	2224-33-1	Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with Butan-2-one O,O',O''-(methylsilylidyne)trioxime (CAS 22984-54-9).	25/06/2015	10/08/2015	Details
dodecamethylpentasiloxane	205-492-2	141-63-9	Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with Decamethyltetrasiloxane (EC 205-491-7).	25/06/2015	10/08/2015	Details
octyltrichlorosilane	226-112-1	5283-66-9	Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with triethoxy(2,4,4-trimethylpentyl)silane (EC 252-558-1, CAS 35435-21-3)	25/06/2015	10/08/2015	Details
potassium 4-isopropylbenzenesulphonate	629-764-9	164524-02-1	Reproductive toxicity (extended one-generation reproductive toxicity study)	25/06/2015	10/08/2015	Details
Reaction mass of sodium hydrogen N-(1-oxooctadecyl)-L-glutamate and stearic acid	939-201-1	-	Reproductive toxicity (pre-natal developmental toxicity)	25/06/2015	10/08/2015	Details
Sodium N-lauroylsarcosinate	205-281-5	137-16-6	Reproductive toxicity (pre-natal developmental toxicity)	25/06/2015	10/08/2015	Details
triethoxy(phenyl)silane	212-305-8	780-69-8	Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with trimethoxy(phenyl)silane (EC 221-066-9, CAS 2996-92-1)	25/06/2015	10/08/2015	Details
trimethoxy(2,4,4-trimethylpentyl)silane	251-995-5	34396-03-7	Sub-chronic toxicity (90-day): oral Note: testing proposed with triethoxy(2,4,4-trimethylpentyl)silane (EC 252-558-1, CAS 35435-21-3) "	25/06/2015	10/08/2015	Details
6'-(dibutylamino)-3'-methyl-2'-(phenylamino)spiro[isobenzofuran-1(3H),9-(9H)-xanthen]-3-one	403-830-5	89331-94-2	Bioaccumulation aquatic / sediment	12/06/2015	27/07/2015	Details

Showing 1,051 - 1,100 of 2,011 results.

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