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Registered substances

Registered substances

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

Please note:
  • The ‘Substance has nanoform’ search filter returns all factsheets containing any data related to nanomaterials. NB: This does not mean that a registration covering nanoforms has been submitted in line with the revised annexes of REACH. Since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA in a new or updated registration dossier.
Last updated 20 July 2021. Database contains 23343 unique substances and contains information from 104192 dossiers.
Substance identity
Administrative data
Submission type:
First published date:
Last update date:
Substance data
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Uses and exposure
Life cycle:
  • Consumer Uses
  • Article service life
  • Widespread uses by professional workers
  • Formulation or re-packing
  • Uses at industrial sites
  • Manufacture
Category:
Details
2,2'-(heptane-1,6-diyl)bis-1,3-dioxolane; reaction mass of: 2,2'-(heptane-1,7-diyl)bis-1,3-dioxolane
428-110-8 - Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
2,2'-but-2-ynylenedioxydiethanol
947-549-0 - Active Intermediate Joint Intermediate use only 12-01-2021 View substance registered dossier
2,2'-{octahydro-1H-4,7-methanoindene-2,5-diylbis[(2,1-phenylene)oxymethylene]}bis(oxirane)
943-519-6 - Active Full Joint ≥ 1 to < 10 tonnes 04-07-2019 View substance registered dossier
2,2,2,4,4,4,4-heptakis[(2-ethylhexanoyl)oxy]cyclodimolybdoxan-2-yl 2-ethylhexanoate
700-831-5 - Active Full Joint ≥ 100 to < 1 000 tonnes 14-10-2013 View substance registered dossier
2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoroheptyl N-[6-({[(2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoroheptyl)oxy]carbonyl}amino)-3,3,5-trimethylhexyl]carbamate 2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoroheptyl N-[6-({[(2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoroheptyl)oxy]carbonyl}amino)-3,5,5-trimethylhexyl]carbamate
938-105-7 - Active Full Individual ≥ 0 to < 10 tonnes 18-10-2012 View substance registered dossier
2,2,3,3,4,4,5,5,6,6-decafluoro-6-trifluorovinyloxyhexanenitrile
443-050-2 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
2,2,6,6-tetramethyl-4-piperidyl acrylate
415-090-0 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2,2,6,6-tetramethyl-4-substituted-piperidinyl-1-oxy
482-430-2 - Active Full Individual ≥ 0 to < 10 tonnes 24-03-2021 View substance registered dossier
2,2,6,6-tetramethylpiperidine-1,4-diol
434-880-6 - Active Full Joint ≥ 10 to < 100 tonnes 07-03-2019 View substance registered dossier
2,2,6,6-tetramethylpiperidine-1,4-diol
434-880-6 - Active NONS Joint Tonnage data confidential 15-12-2008 View substance registered dossier
2,2-bis(3,5-dibromo-4-(3-acryloyloxy-2-hydroxypropoxy)phenyl)propane
436-220-2 - Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
2,2-bis[(allyloxy)methyl]butyl (3-{[({2,2-bis[(allyloxy)methyl]butoxy}carbonyl)amino]methyl}-3,5,5-trimethylcyclohexyl)carbamate
946-937-7 - Active Full Joint ≥ 1 to < 10 tonnes 29-03-2018 View substance registered dossier
2,2-dialkyl-4-hydroxymethyl-1,3-dioxolane; reaction products with ethylene oxide (alkyl is C1-12 and the sum to C13, average degree of ethoxylation is 3.5)
430-580-4 - Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
2,2-dimethyl-3-(m-tolyl)propanal
440-720-6 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2,2-dimethyl-3-(m-tolyl)propanal
440-720-6 - Active Intermediate Joint Intermediate use only 17-04-2020 View substance registered dossier
2,2-dimethyl-4,7-dihydro-1,3-dioxepine
445-850-7 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2,20:3,19-Dimethano-2,3,4a,5a,6a,7a,8a,9a,10a,11a, 12a,13a,14a,15a,16a,17a,19 ,20,21a,22a,23a,24a,25a,26a,27a,28a,29a,30a,31a,32a,33a,34a-dotriacontaazabispentaleno [1''',6''':5'',6'',7''] cycloocta[1'',2'',3'':3'',4'']pentaleno[1'',6'':5',6',7']cycloocta[1',2',3':3',4']pentaleno[1',6':5,6,7]cycloocta[1,2,3-gh:1',2',3'-g'h']cycloocta[1,2,3-cd:5,6,7-c'd']dipentalene-1,4,6,8,10,12,14,16,18,21,23,25,27,29,31,33-hexadecone, hexadecahydro-, stereoisomer,2,18:3,17-Dimethano-2,3, ,4a,5a,6a,7a,8a,9a,10a,11a,12a,13a,14a,15a,17,18,19a, 20a,21a,22a,23a,24a, 25a,26a,27a,28a,29a,30a-octacosaazabispentaleno[1''',6''':5'',6'',7'']cycloocta [1'',2'',3'':3'',4''] pentaleno[1'',6'':5',6',7']cycloocta[1',2',3':3',4']pentaleno[1',6':5,6,7]cycloocta[1,2,3-cd:1',2',3'-gh]pentalene-1,4,6,8,10,12,14,16,19,21,23,25,27,29-tetradecone, tetradecahydro-, stereoisomer, 1H,4H,12H,15H-2,14:3,13-Dimethano-5H,6H,7H,8H,9H,10H,11H,16H,17H,18H,19H,20H,21H,22H-2,3,4a,5a,6a,7a,8a,9a,10a,11a,13,14,15a,16a,17a,18a,19a,20a,21a,22a-eicosaazabispentaleno [1'',6'':5',6',7']cycloocta[1',2',3':3',4']pentaleno[1',6':5,6,7]cycloocta[1,2,3-cd:1',2',3'-gh]pentalene-1,4,6,8,10,12,15,17,19,21-decone, decahydro-, stereoisomer
946-188-6 - Active Full Joint ≥ 1 to < 10 tonnes 05-05-2021 View substance registered dossier
2,2`-[6-(phenylamino)-heteromonocycle-2,4-diyl]diphenol
- - Active Full Individual ≥ 0 to < 10 tonnes 15-02-2013 View substance registered dossier
2,2’-dimethyl-2,2’-azoheptanenitrile; 2-methylheptanenitrile-2-azo-2’-(2’-methylbutanenitrile); 2-methylheptanenitrile-2-azo-2’-(2’-methylpropanenitrile); 2-methylpentanenitrile-2-azo-2’-(2’-methylpropanenitrile); reaction mass of: 2,2’-dimethyl-2,2’-azobutanenitrile
429-710-2 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
2,3,4,4'-tetrakis(6-diazo-5,6-dihydro-5-oxo-1-naphthylsulfonato)benzophenone
424-190-3 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2,3,4,6-Tetra-O-benzyl-D-glucopyranose, Reaction mass of 2,3,4,6-Tetra-O-benzyl-alpha-D-glucopyranose and 2,3,4,6-Tetra-O-benzyl-beta-D-glucopyranose
432-870-6 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
2,3,4,6-Tetra-O-benzyl-D-glucopyranose, Reaction mass of 2,3,4,6-Tetra-O-benzyl-alpha-D-glucopyranose and 2,3,4,6-Tetra-O-benzyl-beta-D-glucopyranose
432-870-6 - Active Intermediate Joint Intermediate use only 24-09-2019 View substance registered dossier
2,3-Difluorpropoxybenzol
485-470-9 - Active NONS Joint Tonnage data confidential 06-01-2020 View substance registered dossier
2,3-dihydro-2-methyl-1H-indol-1-amine p-toluenesulfonate
928-401-4 - Active Intermediate Joint Intermediate use only 18-05-2018 View substance registered dossier
2,3-dimethyl-2-[(3-methylbicyclo[2.2.1]hept-2-yl)methyl]bicyclo[2.2.1]heptane; reaction mass of: 1,7-dimethyl-2-[(3-methylbicyclo[2.2.1]hept-2-yl)methyl]bicyclo[2.2.1]heptane
427-040-5 - Active NONS Joint Tonnage data confidential 15-12-2008 View substance registered dossier
2,4,6-Tri(2,4-dihydroxyphenyl)-1,3,5-triazine
700-796-6 - Active Intermediate Individual Intermediate use only 13-02-2012 View substance registered dossier
2,4,6-Trimethylphenylacetyl chloride
462-070-2 - Active Intermediate Joint Intermediate use only 27-05-2019 View substance registered dossier
2,4-dichlorophenyl [4-(bromomethyl)phenoxy]acetate
432-330-1 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2,4-DPZ
434-170-6 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
2,5-dichloro-3,6-bis{4-[(2-hydroxyethyl)amino]-3-[(2-hydroxyethyl)sulfonyl]anilino}-1,4-benzoquinone
426-700-1 - Cease Manufacture NONS Individual Cease manufacture 28-02-2011 View substance registered dossier
2,5-Dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenylamine
414-940-8 - Cease Manufacture Intermediate Individual Cease manufacture 16-07-2015 View substance registered dossier
2,5-Dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenylamine
414-940-8 - Active NONS Joint Tonnage data confidential 15-12-2008 View substance registered dossier
2,5-dihydroxy-3,6-dimethyl-3,6-bis(dihydroxyphosphinyl)-1,4,2,5-dioxadiphosphorane-2,5-dioxide
921-798-5 - Cease Manufacture Intermediate Joint Cease manufacture 21-09-2018 View substance registered dossier
2,5-dihydroxy-3,6-dimethyl-3,6-bis(dihydroxyphosphinyl)-1,4,2,5-dioxadiphosphorane-2,5-dioxide, hexasodium salt
928-304-7 - Cease Manufacture Full Joint Cease manufacture 25-09-2018 View substance registered dossier
2,5-Dimethylphenylacetyl-chloride
470-780-9 - Active Intermediate Joint Intermediate use only 28-03-2018 View substance registered dossier
2,5-dioxopyrrolidin-1-yl N-{[methyl[[2-(1-methylethyl)-4-thiazolyl]methyl]amino]carbonyl}-.sc.l.sc.-valinate
424-660-8 - Active Intermediate Joint Intermediate use only 13-06-2018 View substance registered dossier
2,5-dioxopyrrolidin-1-yl N-{[methyl[[2-(1-methylethyl)-4-thiazolyl]methyl]amino]carbonyl}-.sc.l.sc.-valinate
424-660-8 - No longer Valid NONS Individual No longer valid 10-11-2008 View substance registered dossier
2,5-diphenyloxazole-4-sulfonic acid
421-210-2 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2,5-furandione, dihydro-, mono- C18- alkenyl derivs. reaction products with potassium hydroxide
947-318-4 - Active Full Joint ≥ 0 to < 10 tonnes 23-03-2018 View substance registered dossier
2,6,6,7,8,8-hexamethyl-3,3a,4,5,5a,6,7,8-octahydro-2H-indeno[4,5-b]furan, 1,1,2,3,3-pentamethyl-1,2,3,5,6,7-hexahydro-4H-inden-4-one and rel-(3aR,7aR)-1,1,2,3,3-pentamethyloctahydro-4H-inden-4-one
946-273-8 - Active Intermediate Joint Intermediate use only 27-11-2017 View substance registered dossier
2,6,6-trimethylcyclohex-1-enecarbonitrile
921-141-2 - Active Intermediate Joint Intermediate use only 19-10-2015 View substance registered dossier
2,6,6-trimethylcyclohexa-1,3-dienecarbonitrile
917-351-9 - Active Intermediate Individual Intermediate use only 02-12-2015 View substance registered dossier
2,6-bis({[bis(2-hydroxyethyl)amino]methyl})-4-[2-(3-{[bis(2-hydroxyethyl)amino]methyl}-4-hydroxyphenyl)propan-2-yl]phenol; 2,6-bis({[bis(2-hydroxyethyl)amino]methyl})-4-[2-(4-hydroxyphenyl)propan-2-yl]phenol; 2-[(2-hydroxyethyl)amino]ethan-1-ol; 2-{[bis(2-hydroxyethyl)amino]methyl}-4-[2-(3-{[bis(2-hydroxyethyl)amino]methyl}-4-hydroxyphenyl)propan-2-yl]phenol; 2-{[bis(2-hydroxyethyl)amino]methyl}-4-[2-(4-hydroxyphenyl)propan-2-yl]phenol; 4-[2-(4-hydroxyphenyl)propan-2-yl]phenol
943-503-9 - Cease Manufacture Full Joint Cease manufacture 12-12-2017 View substance registered dossier
2,6-O,O-di-hexadecanoyl-L-ascorbic acid
424-400-3 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
2,7-Naphthalenedisulfonic acid, 4-substituted-6-[[5-[(substituted-chloroheteromonocyclyl)substituted]-2-substituted-phenyl]azo]-3-[(2,5-disubstituted-phenyl)-azo]-5-hydroxy-, lithium sodium salt
415-420-3 - Active NONS Joint Tonnage data confidential 08-07-2013 View substance registered dossier
2,7-Naphthalenedisulfonic acid, 5-(chloro-(2-(2-substitutedalkoxy)alkylamino)- heteromonocyclylamino)-3-(4-substitutedphenyl)azo)-4-hydroxy-, potassium sodium salt
401-420-0 - Active NONS Joint Tonnage data confidential 19-07-2013 View substance registered dossier
2-((3-(4-Hydroxyphenyl)propanoylamino)benzoic acid
470-130-4 - Active Full Joint ≥ 1 to < 10 tonnes 25-02-2014 View substance registered dossier
2-((8S,10R,11R,13S,14S,16S,17R)-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl ethyl carbonate
945-919-6 - Active Intermediate Joint Intermediate use only 17-10-2017 View substance registered dossier
2-((E)-(4-((4-(1,3-dioxo-1,3-dihydro-2H-hetereocarbapolycyclo-2-yl)alkyl)(ethyl)amino)-2-methyl)diazenyl)-5-nitro-1,3-dicarbonitrile, polyphenyl
- - Active Full Individual ≥ 1 to < 10 tonnes 31-08-2011 View substance registered dossier
2-(1-amino-1-methylethyl)-N-(4-fluorobenzyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxamide
465-070-0 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 2,2'-(heptane-1,6-diyl)bis-1,3-dioxolane; reaction mass of: 2,2'-(heptane-1,7-diyl)bis-1,3-dioxolane 428-110-8 - - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active 2,2'-but-2-ynylenedioxydiethanol 947-549-0 - 2021 View substance registered dossier
Huntsman Advanced Materials (Europe) BV Everslaan 45 B-3078 Everberg Belgium Belgium Active 2,2'-{octahydro-1H-4,7-methanoindene-2,5-diylbis[(2,1-phenylene)oxymethylene]}bis(oxirane) 943-519-6 - 2016; 2019 View substance registered dossier
Axens OR 89, boulevard Franklin Roosevelt B.P. 50802 F-92508 Rueil-Malmaison Cedex France France France Active 2,2,2,4,4,4,4-heptakis[(2-ethylhexanoyl)oxy]cyclodimolybdoxan-2-yl 2-ethylhexanoate 700-831-5 - 2013 View substance registered dossier
[Confidential] - - - 2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoroheptyl N-[6-({[(2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoroheptyl)oxy]carbonyl}amino)-3,3,5-trimethylhexyl]carbamate 2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoroheptyl N-[6-({[(2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoroheptyl)oxy]carbonyl}amino)-3,5,5-trimethylhexyl]carbamate 938-105-7 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active 2,2,3,3,4,4,5,5,6,6-decafluoro-6-trifluorovinyloxyhexanenitrile 443-050-2 - - View substance registered dossier
- - - - 2,2,3,3,4,4,5,5,6,6-decafluoro-6-trifluorovinyloxyhexanenitrile 443-050-2 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active 2,2,6,6-tetramethyl-4-piperidyl acrylate 415-090-0 - - View substance registered dossier
Nufarm GmbH & Co.KG OR St.-Peter-Str.25 4021 Linz Austria Austria Active 2,2,6,6-tetramethyl-4-substituted-piperidinyl-1-oxy 482-430-2 - 2014; 2016; 2021 View substance registered dossier
Nalco Deutschland Manufacturing GmbH und Co. KG Justus-von-Liebig-Strasse 11 64584 Biebesheim Germany Germany Active 2,2,6,6-tetramethylpiperidine-1,4-diol 434-880-6 - - View substance registered dossier
ChampionX Europe BV Oude Rhijnhofweg 17 Oegstgeest 2342BB Leiden Netherlands Netherlands Active 2,2,6,6-tetramethylpiperidine-1,4-diol 434-880-6 - - View substance registered dossier
Nalco Europe B.V. Oude Rhijnhofweg 17 2342 BB Oegstgeest Netherlands Netherlands Active 2,2,6,6-tetramethylpiperidine-1,4-diol 434-880-6 - 2019 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 2,2,6,6-tetramethylpiperidine-1,4-diol 434-880-6 - - View substance registered dossier
Nalco Limited P.O. Box 11, Winnington Avenue, CW8 4DX Northwich, Cheshire United Kingdom United Kingdom No longer Valid 2,2,6,6-tetramethylpiperidine-1,4-diol 434-880-6 - 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 2,2-bis(3,5-dibromo-4-(3-acryloyloxy-2-hydroxypropoxy)phenyl)propane 436-220-2 - - View substance registered dossier
PPG Europe B.V. - OR1 Amsterdamseweg 14 1422 AD Uithoorn Netherlands Netherlands Active 2,2-bis[(allyloxy)methyl]butyl (3-{[({2,2-bis[(allyloxy)methyl]butoxy}carbonyl)amino]methyl}-3,5,5-trimethylcyclohexyl)carbamate 946-937-7 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 2,2-dialkyl-4-hydroxymethyl-1,3-dioxolane; reaction products with ethylene oxide (alkyl is C1-12 and the sum to C13, average degree of ethoxylation is 3.5) 430-580-4 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active 2,2-dimethyl-3-(m-tolyl)propanal 440-720-6 - - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active 2,2-dimethyl-3-(m-tolyl)propanal 440-720-6 - 2011; 2016; 2020 View substance registered dossier
Borregaard AS Hjalmar Wessels vei 6 1701 Sarpsborg Norway Norway Active 2,2-dimethyl-4,7-dihydro-1,3-dioxepine 445-850-7 - - View substance registered dossier
WeylChem Lamotte S.A.S Rue du Flottage B.P. 1 60350 Trosly Breuil France France Active 2,20:3,19-Dimethano-2,3,4a,5a,6a,7a,8a,9a,10a,11a, 12a,13a,14a,15a,16a,17a,19 ,20,21a,22a,23a,24a,25a,26a,27a,28a,29a,30a,31a,32a,33a,34a-dotriacontaazabispentaleno [1''',6''':5'',6'',7''] cycloocta[1'',2'',3'':3'',4'']pentaleno[1'',6'':5',6',7']cycloocta[1',2',3':3',4']pentaleno[1',6':5,6,7]cycloocta[1,2,3-gh:1',2',3'-g'h']cycloocta[1,2,3-cd:5,6,7-c'd']dipentalene-1,4,6,8,10,12,14,16,18,21,23,25,27,29,31,33-hexadecone, hexadecahydro-, stereoisomer,2,18:3,17-Dimethano-2,3, ,4a,5a,6a,7a,8a,9a,10a,11a,12a,13a,14a,15a,17,18,19a, 20a,21a,22a,23a,24a, 25a,26a,27a,28a,29a,30a-octacosaazabispentaleno[1''',6''':5'',6'',7'']cycloocta [1'',2'',3'':3'',4''] pentaleno[1'',6'':5',6',7']cycloocta[1',2',3':3',4']pentaleno[1',6':5,6,7]cycloocta[1,2,3-cd:1',2',3'-gh]pentalene-1,4,6,8,10,12,14,16,19,21,23,25,27,29-tetradecone, tetradecahydro-, stereoisomer, 1H,4H,12H,15H-2,14:3,13-Dimethano-5H,6H,7H,8H,9H,10H,11H,16H,17H,18H,19H,20H,21H,22H-2,3,4a,5a,6a,7a,8a,9a,10a,11a,13,14,15a,16a,17a,18a,19a,20a,21a,22a-eicosaazabispentaleno [1'',6'':5',6',7']cycloocta[1',2',3':3',4']pentaleno[1',6':5,6,7]cycloocta[1,2,3-cd:1',2',3'-gh]pentalene-1,4,6,8,10,12,15,17,19,21-decone, decahydro-, stereoisomer 946-188-6 - - View substance registered dossier
Sterling Pharma Solutions Ltd Dudley NE23 7QG Cramlington Northumberland United Kingdom United Kingdom No longer Valid 2,20:3,19-Dimethano-2,3,4a,5a,6a,7a,8a,9a,10a,11a, 12a,13a,14a,15a,16a,17a,19 ,20,21a,22a,23a,24a,25a,26a,27a,28a,29a,30a,31a,32a,33a,34a-dotriacontaazabispentaleno [1''',6''':5'',6'',7''] cycloocta[1'',2'',3'':3'',4'']pentaleno[1'',6'':5',6',7']cycloocta[1',2',3':3',4']pentaleno[1',6':5,6,7]cycloocta[1,2,3-gh:1',2',3'-g'h']cycloocta[1,2,3-cd:5,6,7-c'd']dipentalene-1,4,6,8,10,12,14,16,18,21,23,25,27,29,31,33-hexadecone, hexadecahydro-, stereoisomer,2,18:3,17-Dimethano-2,3, ,4a,5a,6a,7a,8a,9a,10a,11a,12a,13a,14a,15a,17,18,19a, 20a,21a,22a,23a,24a, 25a,26a,27a,28a,29a,30a-octacosaazabispentaleno[1''',6''':5'',6'',7'']cycloocta [1'',2'',3'':3'',4''] pentaleno[1'',6'':5',6',7']cycloocta[1',2',3':3',4']pentaleno[1',6':5,6,7]cycloocta[1,2,3-cd:1',2',3'-gh]pentalene-1,4,6,8,10,12,14,16,19,21,23,25,27,29-tetradecone, tetradecahydro-, stereoisomer, 1H,4H,12H,15H-2,14:3,13-Dimethano-5H,6H,7H,8H,9H,10H,11H,16H,17H,18H,19H,20H,21H,22H-2,3,4a,5a,6a,7a,8a,9a,10a,11a,13,14,15a,16a,17a,18a,19a,20a,21a,22a-eicosaazabispentaleno [1'',6'':5',6',7']cycloocta[1',2',3':3',4']pentaleno[1',6':5,6,7]cycloocta[1,2,3-cd:1',2',3'-gh]pentalene-1,4,6,8,10,12,15,17,19,21-decone, decahydro-, stereoisomer 946-188-6 - 2021 View substance registered dossier
Aqdot Ireland Limited 88 Harcourt Street 2, D02Dk18 Dublin Ireland Ireland Active 2,20:3,19-Dimethano-2,3,4a,5a,6a,7a,8a,9a,10a,11a, 12a,13a,14a,15a,16a,17a,19 ,20,21a,22a,23a,24a,25a,26a,27a,28a,29a,30a,31a,32a,33a,34a-dotriacontaazabispentaleno [1''',6''':5'',6'',7''] cycloocta[1'',2'',3'':3'',4'']pentaleno[1'',6'':5',6',7']cycloocta[1',2',3':3',4']pentaleno[1',6':5,6,7]cycloocta[1,2,3-gh:1',2',3'-g'h']cycloocta[1,2,3-cd:5,6,7-c'd']dipentalene-1,4,6,8,10,12,14,16,18,21,23,25,27,29,31,33-hexadecone, hexadecahydro-, stereoisomer,2,18:3,17-Dimethano-2,3, ,4a,5a,6a,7a,8a,9a,10a,11a,12a,13a,14a,15a,17,18,19a, 20a,21a,22a,23a,24a, 25a,26a,27a,28a,29a,30a-octacosaazabispentaleno[1''',6''':5'',6'',7'']cycloocta [1'',2'',3'':3'',4''] pentaleno[1'',6'':5',6',7']cycloocta[1',2',3':3',4']pentaleno[1',6':5,6,7]cycloocta[1,2,3-cd:1',2',3'-gh]pentalene-1,4,6,8,10,12,14,16,19,21,23,25,27,29-tetradecone, tetradecahydro-, stereoisomer, 1H,4H,12H,15H-2,14:3,13-Dimethano-5H,6H,7H,8H,9H,10H,11H,16H,17H,18H,19H,20H,21H,22H-2,3,4a,5a,6a,7a,8a,9a,10a,11a,13,14,15a,16a,17a,18a,19a,20a,21a,22a-eicosaazabispentaleno [1'',6'':5',6',7']cycloocta[1',2',3':3',4']pentaleno[1',6':5,6,7]cycloocta[1,2,3-cd:1',2',3'-gh]pentalene-1,4,6,8,10,12,15,17,19,21-decone, decahydro-, stereoisomer 946-188-6 - 2019; 2021 View substance registered dossier
Archroma Germany GmbH Kasteler Str. 45 65203 Wiesbaden Germany Germany Active 2,2`-[6-(phenylamino)-heteromonocycle-2,4-diyl]diphenol - - 2008; 2011; 2013 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority. - - Active 2,2’-dimethyl-2,2’-azoheptanenitrile; 2-methylheptanenitrile-2-azo-2’-(2’-methylbutanenitrile); 2-methylheptanenitrile-2-azo-2’-(2’-methylpropanenitrile); 2-methylpentanenitrile-2-azo-2’-(2’-methylpropanenitrile); reaction mass of: 2,2’-dimethyl-2,2’-azobutanenitrile 429-710-2 - - View substance registered dossier
- - - - 2,3,4,4'-tetrakis(6-diazo-5,6-dihydro-5-oxo-1-naphthylsulfonato)benzophenone 424-190-3 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active 2,3,4,6-Tetra-O-benzyl-D-glucopyranose, Reaction mass of 2,3,4,6-Tetra-O-benzyl-alpha-D-glucopyranose and 2,3,4,6-Tetra-O-benzyl-beta-D-glucopyranose 432-870-6 - - View substance registered dossier
Biosynth s.r.o. Nobelova 34 83605 Bratislava Slovakia Slovakia Active 2,3,4,6-Tetra-O-benzyl-D-glucopyranose, Reaction mass of 2,3,4,6-Tetra-O-benzyl-alpha-D-glucopyranose and 2,3,4,6-Tetra-O-benzyl-beta-D-glucopyranose 432-870-6 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 2,3-Difluorpropoxybenzol 485-470-9 - 2020 View substance registered dossier
Laboratori Alchemia Srl San Faustino 68 20134 Milan Italy Italy Active 2,3-dihydro-2-methyl-1H-indol-1-amine p-toluenesulfonate 928-401-4 - - View substance registered dossier
Covance Clinical Development SA 046 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 – 5 Planta 28050 Madrid Spain Spain Active 2,3-dimethyl-2-[(3-methylbicyclo[2.2.1]hept-2-yl)methyl]bicyclo[2.2.1]heptane; reaction mass of: 1,7-dimethyl-2-[(3-methylbicyclo[2.2.1]hept-2-yl)methyl]bicyclo[2.2.1]heptane 427-040-5 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 2,3-dimethyl-2-[(3-methylbicyclo[2.2.1]hept-2-yl)methyl]bicyclo[2.2.1]heptane; reaction mass of: 1,7-dimethyl-2-[(3-methylbicyclo[2.2.1]hept-2-yl)methyl]bicyclo[2.2.1]heptane 427-040-5 - - View substance registered dossier
BASF Grenzach GmbH Köchlinstr. 1 79639 Grenzach-Wyhlen Germany Germany Active 2,4,6-Tri(2,4-dihydroxyphenyl)-1,3,5-triazine 700-796-6 - - View substance registered dossier
WeylChem Lamotte S.A.S Rue du Flottage B.P. 1 60350 Trosly Breuil France France Active 2,4,6-Trimethylphenylacetyl chloride 462-070-2 - 2016; 2019 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active 2,4,6-Trimethylphenylacetyl chloride 462-070-2 - 2010; 2016 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 2,4-dichlorophenyl [4-(bromomethyl)phenoxy]acetate 432-330-1 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 2,4-DPZ 434-170-6 - - View substance registered dossier
DyStar Colours Distribution GmbH Am Prime-Parc 12 65479 Raunheim Germany Germany Cease Manufacture 2,5-dichloro-3,6-bis{4-[(2-hydroxyethyl)amino]-3-[(2-hydroxyethyl)sulfonyl]anilino}-1,4-benzoquinone 426-700-1 - 2019 View substance registered dossier
AllessaProduktion GmbH Alt-Fechenheim 34 60386 Frankfurt am Main Germany Germany Cease Manufacture 2,5-Dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenylamine 414-940-8 - 2019 View substance registered dossier
Syngenta Ltd Jealott’s Hill International Research Centre RG42 6EY Bracknell Berkshire United Kingdom United Kingdom No longer Valid 2,5-Dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenylamine 414-940-8 - 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 2,5-Dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenylamine 414-940-8 - - View substance registered dossier
Cytec Industries BV OR for UK Burgemeester van Lierplein 75 3134 ZB Vlaardingen Netherlands Netherlands Cease Manufacture 2,5-dihydroxy-3,6-dimethyl-3,6-bis(dihydroxyphosphinyl)-1,4,2,5-dioxadiphosphorane-2,5-dioxide 921-798-5 - 2021 View substance registered dossier
Thomas Swan & Co. Ltd. Rotary Way DH8 7ND Consett Co. Durham United Kingdom United Kingdom No longer Valid 2,5-dihydroxy-3,6-dimethyl-3,6-bis(dihydroxyphosphinyl)-1,4,2,5-dioxadiphosphorane-2,5-dioxide, hexasodium salt 928-304-7 - 2021 View substance registered dossier
Cytec Industries BV OR for UK Burgemeester van Lierplein 75 3134 ZB Vlaardingen Netherlands Netherlands Cease Manufacture 2,5-dihydroxy-3,6-dimethyl-3,6-bis(dihydroxyphosphinyl)-1,4,2,5-dioxadiphosphorane-2,5-dioxide, hexasodium salt 928-304-7 - 2021 View substance registered dossier
WeylChem Lamotte S.A.S Rue du Flottage B.P. 1 60350 Trosly Breuil France France Cease Manufacture 2,5-Dimethylphenylacetyl-chloride 470-780-9 - 2019 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active 2,5-Dimethylphenylacetyl-chloride 470-780-9 - 2010 View substance registered dossier
AbbVie Srl S.R. 148 Pontina Km 52 snc 04011 Campoverde di Aprilia (LT) Italy Italy Active 2,5-dioxopyrrolidin-1-yl N-{[methyl[[2-(1-methylethyl)-4-thiazolyl]methyl]amino]carbonyl}-.sc.l.sc.-valinate 424-660-8 - 2011; 2018 View substance registered dossier
Fine Organics Limited Seal Sands TS2 1UB Middlesbrough Teesside United Kingdom United Kingdom No longer Valid 2,5-dioxopyrrolidin-1-yl N-{[methyl[[2-(1-methylethyl)-4-thiazolyl]methyl]amino]carbonyl}-.sc.l.sc.-valinate 424-660-8 - 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 2,5-diphenyloxazole-4-sulfonic acid 421-210-2 - - View substance registered dossier
Italmatch Chemicals SpA - OR 2 Via Magazzini del Cotone 17 – modulo 4 16128 genova Italy Italy Active 2,5-furandione, dihydro-, mono- C18- alkenyl derivs. reaction products with potassium hydroxide 947-318-4 - - View substance registered dossier
IFF Benicarlo, S.L. Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain Spain Active 2,6,6,7,8,8-hexamethyl-3,3a,4,5,5a,6,7,8-octahydro-2H-indeno[4,5-b]furan, 1,1,2,3,3-pentamethyl-1,2,3,5,6,7-hexahydro-4H-inden-4-one and rel-(3aR,7aR)-1,1,2,3,3-pentamethyloctahydro-4H-inden-4-one 946-273-8 - - View substance registered dossier
Givaudan Iberica SA Pla d'en Batlle s/n 08470 San Celoni Barcelona Spain Spain Active 2,6,6-trimethylcyclohex-1-enecarbonitrile 921-141-2 - - View substance registered dossier
Givaudan Iberica SA Pla d'en Batlle s/n 08470 San Celoni Barcelona Spain Spain Active 2,6,6-trimethylcyclohexa-1,3-dienecarbonitrile 917-351-9 - - View substance registered dossier
Plixxent B.V. Korte Groningerweg 1A 9607 Foxhol Netherlands Netherlands Cease Manufacture 2,6-bis({[bis(2-hydroxyethyl)amino]methyl})-4-[2-(3-{[bis(2-hydroxyethyl)amino]methyl}-4-hydroxyphenyl)propan-2-yl]phenol; 2,6-bis({[bis(2-hydroxyethyl)amino]methyl})-4-[2-(4-hydroxyphenyl)propan-2-yl]phenol; 2-[(2-hydroxyethyl)amino]ethan-1-ol; 2-{[bis(2-hydroxyethyl)amino]methyl}-4-[2-(3-{[bis(2-hydroxyethyl)amino]methyl}-4-hydroxyphenyl)propan-2-yl]phenol; 2-{[bis(2-hydroxyethyl)amino]methyl}-4-[2-(4-hydroxyphenyl)propan-2-yl]phenol; 4-[2-(4-hydroxyphenyl)propan-2-yl]phenol 943-503-9 - 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. - - Active 2,6-O,O-di-hexadecanoyl-L-ascorbic acid 424-400-3 - - View substance registered dossier
- - - - 2,6-O,O-di-hexadecanoyl-L-ascorbic acid 424-400-3 - - View substance registered dossier
Huntsman Textile Effects (Germany) GmbH Rehlinger Str. 1 D-86462 Langweid a.Lech Germany Germany Active 2,7-Naphthalenedisulfonic acid, 4-substituted-6-[[5-[(substituted-chloroheteromonocyclyl)substituted]-2-substituted-phenyl]azo]-3-[(2,5-disubstituted-phenyl)-azo]-5-hydroxy-, lithium sodium salt 415-420-3 - 2011; 2013 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority. - - Active 2,7-Naphthalenedisulfonic acid, 4-substituted-6-[[5-[(substituted-chloroheteromonocyclyl)substituted]-2-substituted-phenyl]azo]-3-[(2,5-disubstituted-phenyl)-azo]-5-hydroxy-, lithium sodium salt 415-420-3 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Swedish competent national authority. - - Active 2,7-Naphthalenedisulfonic acid, 5-(chloro-(2-(2-substitutedalkoxy)alkylamino)- heteromonocyclylamino)-3-(4-substitutedphenyl)azo)-4-hydroxy-, potassium sodium salt 401-420-0 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority. - - Active 2,7-Naphthalenedisulfonic acid, 5-(chloro-(2-(2-substitutedalkoxy)alkylamino)- heteromonocyclylamino)-3-(4-substitutedphenyl)azo)-4-hydroxy-, potassium sodium salt 401-420-0 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active 2,7-Naphthalenedisulfonic acid, 5-(chloro-(2-(2-substitutedalkoxy)alkylamino)- heteromonocyclylamino)-3-(4-substitutedphenyl)azo)-4-hydroxy-, potassium sodium salt 401-420-0 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Danish competent national authority. - - Active 2,7-Naphthalenedisulfonic acid, 5-(chloro-(2-(2-substitutedalkoxy)alkylamino)- heteromonocyclylamino)-3-(4-substitutedphenyl)azo)-4-hydroxy-, potassium sodium salt 401-420-0 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Finnish competent national authority. - - Active 2,7-Naphthalenedisulfonic acid, 5-(chloro-(2-(2-substitutedalkoxy)alkylamino)- heteromonocyclylamino)-3-(4-substitutedphenyl)azo)-4-hydroxy-, potassium sodium salt 401-420-0 - - View substance registered dossier
Huntsman Textile Effects (Germany) GmbH Rehlinger Str. 1 D-86462 Langweid a.Lech Germany Germany Active 2,7-Naphthalenedisulfonic acid, 5-(chloro-(2-(2-substitutedalkoxy)alkylamino)- heteromonocyclylamino)-3-(4-substitutedphenyl)azo)-4-hydroxy-, potassium sodium salt 401-420-0 - 2010; 2013 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active 2,7-Naphthalenedisulfonic acid, 5-(chloro-(2-(2-substitutedalkoxy)alkylamino)- heteromonocyclylamino)-3-(4-substitutedphenyl)azo)-4-hydroxy-, potassium sodium salt 401-420-0 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 2,7-Naphthalenedisulfonic acid, 5-(chloro-(2-(2-substitutedalkoxy)alkylamino)- heteromonocyclylamino)-3-(4-substitutedphenyl)azo)-4-hydroxy-, potassium sodium salt 401-420-0 - - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active 2-((3-(4-Hydroxyphenyl)propanoylamino)benzoic acid 470-130-4 - 2014 View substance registered dossier
NEWCHEM S.P.A. VIA EDMONDO DE AMICIS 47 20123 MILANO ITALY Italy Italy Active 2-((8S,10R,11R,13S,14S,16S,17R)-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl ethyl carbonate 945-919-6 - - View substance registered dossier
Huntsman Textile Effects (Germany) GmbH Rehlinger Str. 1 D-86462 Langweid a.Lech Germany Germany Active 2-((E)-(4-((4-(1,3-dioxo-1,3-dihydro-2H-hetereocarbapolycyclo-2-yl)alkyl)(ethyl)amino)-2-methyl)diazenyl)-5-nitro-1,3-dicarbonitrile, polyphenyl - - 2011 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 2-(1-amino-1-methylethyl)-N-(4-fluorobenzyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxamide 465-070-0 - - View substance registered dossier

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